标题
Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
作者
关键词
-
出版物
Journal of Neuroinflammation
Volume 15, Issue 1, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-09-24
DOI
10.1186/s12974-018-1313-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis
- (2018) Vittorio Calabrese et al. FREE RADICAL BIOLOGY AND MEDICINE
- High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
- (2018) Dunja Mrdjen et al. IMMUNITY
- TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse
- (2018) G. Aleph Prieto et al. NEUROCHEMICAL RESEARCH
- TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
- (2018) Yingjun Zhao et al. NEURON
- The effects of exercise on hypothalamic neurodegeneration of Alzheimer’s disease mouse model
- (2018) Khoa Do et al. PLoS One
- Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response
- (2018) Xinghua Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
- (2018) Liping Zhao et al. SCIENCE
- Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development
- (2018) Ilia D. Vainchtein et al. SCIENCE
- Improved Spatial Learning Strategy and Memory in Aged Alzheimer AβPPswe/PS1dE9 Mice on a Multi-Nutrient Diet
- (2018) Maximilian Wiesmann et al. JOURNAL OF ALZHEIMERS DISEASE
- Restoration of Lipoxin A4 Signaling Reduces Alzheimer's Disease-Like Pathology in the 3xTg-AD Mouse Model
- (2018) Haley C. Dunn et al. JOURNAL OF ALZHEIMERS DISEASE
- Can a Bacterial Endotoxin be a Key Factor in the Kinetics of Amyloid Fibril Formation?
- (2018) Annalia Asti et al. JOURNAL OF ALZHEIMERS DISEASE
- Innate immune memory in the brain shapes neurological disease hallmarks
- (2018) Ann-Christin Wendeln et al. NATURE
- Microglial repopulation resolves inflammation and promotes brain recovery after injury
- (2017) Rachel A. Rice et al. GLIA
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Reactive Astrocytes: Production, Function, and Therapeutic Potential
- (2017) Shane A. Liddelow et al. IMMUNITY
- Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer’s Mouse Model
- (2017) Carolin Brandscheid et al. JOURNAL OF ALZHEIMERS DISEASE
- Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer’s Disease
- (2017) Yujiao Lu et al. JOURNAL OF ALZHEIMERS DISEASE
- Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury
- (2017) Izhar Livne-Bar et al. JOURNAL OF CLINICAL INVESTIGATION
- Astrocytic tight junctions control inflammatory CNS lesion pathogenesis
- (2017) Sam Horng et al. JOURNAL OF CLINICAL INVESTIGATION
- Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity
- (2017) Eva Czirr et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nonclassical Monocytes Mediate Secondary Injury, Neurocognitive Outcome, and Neutrophil Infiltration after Traumatic Brain Injury
- (2017) Hadijat M. Makinde et al. JOURNAL OF IMMUNOLOGY
- Astrocytes contribute to Aβ-induced blood-brain barrier damage through activation of endothelial MMP9
- (2017) Simona Federica Spampinato et al. JOURNAL OF NEUROCHEMISTRY
- Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition
- (2017) Chia-Chen Liu et al. JOURNAL OF NEUROSCIENCE
- Early heparin administration after traumatic brain injury
- (2017) Katsuhiro Nagata et al. Journal of Trauma and Acute Care Surgery
- Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss
- (2017) Michael X. Hernandez et al. Molecular Neurodegeneration
- TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
- (2017) Shane M. Bemiller et al. Molecular Neurodegeneration
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
- (2017) Thais F Galatro et al. NATURE NEUROSCIENCE
- Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
- (2017) Petra Füger et al. NATURE NEUROSCIENCE
- A new fate mapping system reveals context-dependent random or clonal expansion of microglia
- (2017) Tuan Leng Tay et al. NATURE NEUROSCIENCE
- Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier
- (2017) Doreen Osgood et al. NEUROBIOLOGY OF AGING
- Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
- (2017) Annamaria Cattaneo et al. NEUROBIOLOGY OF AGING
- Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury
- (2017) Emilie L. Castranio et al. NEUROBIOLOGY OF DISEASE
- Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease
- (2017) Jennifer M. Walker et al. NEUROBIOLOGY OF DISEASE
- Midlife systemic inflammatory markers are associated with late-life brain volume
- (2017) Keenan A. Walker et al. NEUROLOGY
- Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models
- (2017) Egle Cekanaviciute et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway
- (2017) Yosuke M. Morizawa et al. Nature Communications
- ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
- (2017) Jiqing Cao et al. Scientific Reports
- Analysis of inflammatory cytokine and TLR expression levels in Type 2 Diabetes with complications
- (2017) Saket Gupta et al. Scientific Reports
- Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain
- (2017) Katharine Askew et al. Cell Reports
- Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation
- (2017) Cláudia Caldeira et al. Frontiers in Aging Neuroscience
- Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link
- (2017) Ryusuke Takechi et al. Frontiers in Aging Neuroscience
- The role of microbial amyloid in neurodegeneration
- (2017) Robert P. Friedland et al. PLoS Pathogens
- Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus
- (2017) Yuhai Zhao et al. Frontiers in Cellular and Infection Microbiology
- Early heparin administration after traumatic brain injury
- (2017) Katsuhiro Nagata et al. Journal of Trauma and Acute Care Surgery
- Strength Training Decreases Inflammation and Increases Cognition and Physical Fitness in Older Women with Cognitive Impairment
- (2017) Matheus U. Chupel et al. Frontiers in Physiology
- Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice
- (2017) Floris Fransen et al. Frontiers in Immunology
- Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment
- (2017) Zsuzsanna Tucsek et al. GeroScience
- Increased ATP-Binding Cassette Transporter A1 Expression in Alzheimer's Disease Hippocampal Neurons
- (2017) Woojin Scott Kim et al. JOURNAL OF ALZHEIMERS DISEASE
- Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota
- (2017) T. Harach et al. Scientific Reports
- TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia
- (2017) Su-Man Kim et al. Scientific Reports
- Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer’s disease
- (2017) Myles R. Minter et al. Scientific Reports
- Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
- (2017) Erika Castillo et al. Scientific Reports
- Gut microbiome alterations in Alzheimer’s disease
- (2017) Nicholas M. Vogt et al. Scientific Reports
- Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
- (2016) Elisabeth Sanchez-Mejias et al. ACTA NEUROPATHOLOGICA
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
- (2016) Elizabeth E. Spangenberg et al. BRAIN
- Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity
- (2016) Shuai Hao et al. BRAIN BEHAVIOR AND IMMUNITY
- The 5-Lipoxygenase as modulator of Alzheimer’s γ-secretase and therapeutic target
- (2016) Jin Chu et al. BRAIN RESEARCH BULLETIN
- sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
- (2016) Marc Suárez‐Calvet et al. EMBO Molecular Medicine
- Physical activity and inflammation: effects on gray-matter volume and cognitive decline in aging
- (2016) Goran Papenberg et al. HUMAN BRAIN MAPPING
- ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain
- (2016) YuHong Fu et al. JOURNAL OF ALZHEIMERS DISEASE
- Increased Amyloid Precursor Protein and Tau Expression Manifests as Key Secondary Cell Death in Chronic Traumatic Brain Injury
- (2016) Sandra A. Acosta et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inflammasomes link vascular disease with neuroinflammation and brain disorders
- (2016) Nikolett Lénárt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
- (2016) Longyu Yang et al. Journal of Neuroinflammation
- The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice
- (2016) Molly Stanley et al. JOURNAL OF NEUROSCIENCE
- Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
- (2016) Taylor R. Jay et al. JOURNAL OF NEUROSCIENCE
- TREM2/DAP12 Signal Elicits Proinflammatory Response in Microglia and Exacerbates Neuropathic Pain
- (2016) M. Kobayashi et al. JOURNAL OF NEUROSCIENCE
- Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning
- (2016) Frank C.G. van Bussel et al. MEDICINE
- Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
- (2016) Amanda Heslegrave et al. Molecular Neurodegeneration
- Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer’s disease-related signaling
- (2016) D A Bangasser et al. MOLECULAR PSYCHIATRY
- Astrocyte scar formation aids central nervous system axon regeneration
- (2016) Mark A. Anderson et al. NATURE
- Age-related myelin degradation burdens the clearance function of microglia during aging
- (2016) Shima Safaiyan et al. NATURE NEUROSCIENCE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- Resolution of inflammation: a new therapeutic frontier
- (2016) James N. Fullerton et al. NATURE REVIEWS DRUG DISCOVERY
- Gram-negative bacterial molecules associate with Alzheimer disease pathology
- (2016) Xinhua Zhan et al. NEUROLOGY
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Inhibitory control in obesity and binge eating disorder: A systematic review and meta-analysis of neurocognitive and neuroimaging studies
- (2016) Luca Lavagnino et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice
- (2016) Montasir Elahi et al. NEUROSCIENCE LETTERS
- Inhibition of chemokine-like factor 1 improves blood-brain barrier dysfunction in rats following focal cerebral ischemia
- (2016) Ling-Lei Kong et al. NEUROSCIENCE LETTERS
- A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus
- (2016) Elizabeth A. McKie et al. PLoS One
- LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response
- (2016) Elisabetta Mantuano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model
- (2016) Loukia Katsouri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline
- (2016) Amy K. Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain
- (2016) Maciej J. Lazarczyk et al. Scientific Reports
- Human gut microbiota: the links with dementia development
- (2016) Rashad Alkasir et al. Protein & Cell
- The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury
- (2016) Stephanie Plummer et al. Aging and Disease
- LRP1 expression in microglia is protective during CNS autoimmunity
- (2016) Tzu-Ying Chuang et al. Acta Neuropathologica Communications
- Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy
- (2016) Antonio Piras et al. Acta Neuropathologica Communications
- Fasting Glucose Level Modulates Cell Surface Expression of CD11b and CD66b in Granulocytes and Monocytes of Patients With Type 2 Diabetes
- (2016) Peter Horvath et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Rapid and label-free microfluidic neutrophil purification and phenotyping in diabetes mellitus
- (2016) Han Wei Hou et al. Scientific Reports
- Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes
- (2015) Corinna Bliederhaeuser et al. ACTA NEUROPATHOLOGICA
- High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice
- (2015) Roel A van der Heijden et al. Aging-US
- Resolution of inflammation is altered in Alzheimer's disease
- (2015) Xiuzhe Wang et al. Alzheimers & Dementia
- TNF-α knockdown alleviates palmitate-induced insulin resistance in C2C12 skeletal muscle cells
- (2015) Karimeh Haghani et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity
- (2015) Annadora J. Bruce-Keller et al. BIOLOGICAL PSYCHIATRY
- Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
- (2015) Nicole Maphis et al. BRAIN
- Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling
- (2015) Samia Habbas et al. CELL
- Cardiovascular risk factors and cognitive decline in older people with type 2 diabetes
- (2015) Insa Feinkohl et al. DIABETOLOGIA
- On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death
- (2015) Douglas B. Kell et al. Integrative Biology
- Reduced cortical BACE1 content with one bout of exercise is accompanied by declines in AMPK, Akt, and MAPK signaling in obese, glucose-intolerant mice
- (2015) R. E. K. MacPherson et al. JOURNAL OF APPLIED PHYSIOLOGY
- Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485Phosphorylation
- (2015) Bhumsoo Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier
- (2015) Steffen E. Storck et al. JOURNAL OF CLINICAL INVESTIGATION
- Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
- (2015) Nabil N. Dagher et al. Journal of Neuroinflammation
- Risk factors for predicting progression from mild cognitive impairment to Alzheimer’s disease: a systematic review and meta-analysis of cohort studies
- (2015) Jie-Qiong Li et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy
- (2015) J. B. Hunt et al. JOURNAL OF NEUROSCIENCE
- Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice
- (2015) D. R. Thakker et al. JOURNAL OF NEUROSCIENCE
- SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1
- (2015) S.-H. Cho et al. JOURNAL OF NEUROSCIENCE
- Clinical evidence of inflammation driving secondary brain injury
- (2015) Holly E. Hinson et al. Journal of Trauma and Acute Care Surgery
- Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
- (2015) Stacy Steinberg et al. NATURE GENETICS
- CD33 modulates TREM2: convergence of Alzheimer loci
- (2015) Gail Chan et al. NATURE NEUROSCIENCE
- Depletion of microglia and inhibition of exosome synthesis halt tau propagation
- (2015) Hirohide Asai et al. NATURE NEUROSCIENCE
- Age- and location-related changes in microglial function
- (2015) Rodney M. Ritzel et al. NEUROBIOLOGY OF AGING
- Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex
- (2015) Douglas G. Walker et al. NEUROBIOLOGY OF AGING
- Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology
- (2015) Marie-Victoire Guillot-Sestier et al. NEURON
- IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior
- (2015) Paramita Chakrabarty et al. NEURON
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus
- (2015) G. Aleph Prieto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer’s Disease: Impacts on Cognitive Decline
- (2015) Jennifer Walker et al. Nutrients
- Lactobacillus fermentumNS9 restores the antibiotic induced physiological and psychological abnormalities in rats
- (2015) T. Wang et al. Beneficial Microbes
- Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
- (2015) Mina Elahy et al. Immunity & Ageing
- Clinical evidence of inflammation driving secondary brain injury
- (2015) Holly E. Hinson et al. Journal of Trauma and Acute Care Surgery
- Inflammation and Neuroprotection in Traumatic Brain Injury
- (2015) Kara N. Corps et al. JAMA Neurology
- Immune aging, dysmetabolism, and inflammation in neurological diseases
- (2015) Michela Deleidi et al. Frontiers in Neuroscience
- Loss of tau rescues inflammation-mediated neurodegeneration
- (2015) Nicole Maphis et al. Frontiers in Neuroscience
- Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians
- (2015) Yasumichi Arai et al. EBioMedicine
- High-Fat Diet-Induced Adiposity, Adipose Inflammation, Hepatic Steatosis and Hyperinsulinemia in Outbred CD-1 Mice
- (2015) Mingming Gao et al. PLoS One
- Impairment of in vivo calcium signaling in amyloid plaque-associated microglia
- (2014) Bianca Brawek et al. ACTA NEUROPATHOLOGICA
- Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats
- (2014) Andrea Špolcová et al. BMC NEUROSCIENCE
- Role of Gut Microbiota in Obesity, Type 2 Diabetes and Alzheimer’s Disease
- (2014) Muhammad Naseer et al. CNS & Neurological Disorders-Drug Targets
- Factors associated with cognitive decline in older adults with type 2 diabetes mellitus during a 6-year observation
- (2014) Hiroyuki Umegaki et al. Geriatrics & Gerontology International
- CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility
- (2014) T. Raj et al. HUMAN MOLECULAR GENETICS
- Angiotensin AT2 receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages via increased interleukin-10 production
- (2014) Isha Dhande et al. HYPERTENSION RESEARCH
- Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
- (2014) Yang Yu et al. JOURNAL OF NEURAL TRANSMISSION
- Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
- (2014) Gustavo A Rodriguez et al. Journal of Neuroinflammation
- Opposing Effects of Membrane-Anchored CX3CL1 on Amyloid and Tau Pathologies via the p38 MAPK Pathway
- (2014) S. Lee et al. JOURNAL OF NEUROSCIENCE
- Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
- (2014) N. S. Woodling et al. JOURNAL OF NEUROSCIENCE
- IKK Deficiency in Myeloid Cells Ameliorates Alzheimer's Disease-Related Symptoms and Pathology
- (2014) Y. Liu et al. JOURNAL OF NEUROSCIENCE
- Activation of NF-κB Mediates Astrocyte Swelling and Brain Edema in Traumatic Brain Injury
- (2014) Arumugam R. Jayakumar et al. JOURNAL OF NEUROTRAUMA
- Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer’s Disease: a Comparative Overview
- (2014) Frederic Brosseron et al. MOLECULAR NEUROBIOLOGY
- Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
- (2014) Yang Zhan et al. NATURE NEUROSCIENCE
- Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
- (2014) Teng Jiang et al. NEUROPSYCHOPHARMACOLOGY
- Chronic Neurodegeneration After Traumatic Brain Injury: Alzheimer Disease, Chronic Traumatic Encephalopathy, or Persistent Neuroinflammation?
- (2014) Alan I. Faden et al. Neurotherapeutics
- Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP
- (2014) Eleonora Distrutti et al. PLoS One
- Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes
- (2014) Yue Wang et al. PLoS One
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Progranulin in neurodegenerative disease
- (2014) Terri L. Petkau et al. TRENDS IN NEUROSCIENCES
- Hypertension in Obese Type 2 Diabetes Patients is Associated with Increases in Insulin Resistance and IL-6 Cytokine Levels: Potential Targets for an Efficient Preventive Intervention
- (2014) Ljiljana Lukic et al. International Journal of Environmental Research and Public Health
- Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus
- (2014) Jinhua Ma et al. Molecular Brain
- Aspirin-Triggered Lipoxin A4 Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice
- (2013) Rodrigo Medeiros et al. AMERICAN JOURNAL OF PATHOLOGY
- Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice
- (2013) Eun-Bum Kang et al. APOPTOSIS
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Clinical and Subclinical Macrovascular Disease as Predictors of Cognitive Decline in Older Patients With Type 2 Diabetes
- (2013) Insa Feinkohl et al. DIABETES CARE
- CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
- (2013) M. Malik et al. JOURNAL OF NEUROSCIENCE
- Sustained Interleukin-1 Overexpression Exacerbates Tau Pathology Despite Reduced Amyloid Burden in an Alzheimer's Mouse Model
- (2013) S. Ghosh et al. JOURNAL OF NEUROSCIENCE
- Neuronal Clearance of Amyloid- by Endocytic Receptor LRP1
- (2013) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Learning and memory ... and the immune system
- (2013) I. Marin et al. LEARNING & MEMORY
- Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex
- (2013) G. A. Rodriguez et al. LEARNING & MEMORY
- β-Amyloid-induced cognitive dysfunction impairs glucose homeostasis by increasing insulin resistance and decreasing β-cell mass in non-diabetic and diabetic rats
- (2013) Sunmin Park et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Transcranial amelioration of inflammation and cell death after brain injury
- (2013) Theodore L. Roth et al. NATURE
- CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
- (2013) Elizabeth M Bradshaw et al. NATURE NEUROSCIENCE
- Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
- (2013) Marie Orre et al. NEUROBIOLOGY OF AGING
- ABCA1 influences neuroinflammation and neuronal death
- (2013) Joanna M. Karasinska et al. NEUROBIOLOGY OF DISEASE
- Expression of the NLRP3 Inflammasome in Cerebral Cortex After Traumatic Brain Injury in a Rat Model
- (2013) Huan-Dong Liu et al. NEUROCHEMICAL RESEARCH
- Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
- (2013) Kurt M. Lucin et al. NEURON
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease
- (2013) Carlos Cruchaga et al. NEURON
- Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats
- (2013) Sung-Eun Kim et al. NEUROSCIENCE LETTERS
- ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status
- (2013) Jared B. Vasquez et al. NEUROSCIENCE LETTERS
- Inflammatory Cytokine Gene Expression in Mesenteric Adipose Tissue during Acute Experimental Colitis
- (2013) W. Conan Mustain et al. PLoS One
- Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology
- (2013) J.-P. Michaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
- (2013) A. Everard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prolonged elevation in hippocampal Aβ and cognitive deficits following repeated endotoxin exposure in the mouse
- (2012) Marielle S. Kahn et al. BEHAVIOURAL BRAIN RESEARCH
- High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes
- (2012) Yolanda Gonzalez et al. BMC IMMUNOLOGY
- Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury
- (2012) Frances Corrigan et al. BRAIN RESEARCH
- Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes
- (2012) Hye-Mi Lee et al. DIABETES
- Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
- (2012) K. D. Copps et al. DIABETOLOGIA
- APOE genotype alters glial activation and loss of synaptic markers in mice
- (2012) Yuangui Zhu et al. GLIA
- A High-Fat Diet Increases IL-1, IL-6, and TNF-α Production by Increasing NF-κB and Attenuating PPAR-γ Expression in Bone Marrow Mesenchymal Stem Cells
- (2012) Mayara Cortez et al. INFLAMMATION
- Identification of the Low Density Lipoprotein (LDL) Receptor-related Protein-1 Interactome in Central Nervous System Myelin Suggests a Role in the Clearance of Necrotic Cell Debris
- (2012) Anthony Fernandez-Castaneda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations
- (2012) Linda Chami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes
- (2012) Naoki Yamamoto et al. JOURNAL OF NEUROCHEMISTRY
- Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
- (2012) David H Cribbs et al. Journal of Neuroinflammation
- Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice
- (2012) Ellinor Kenne et al. Journal of Neuroinflammation
- Risk for late-life re-injury, dementia and death among individuals with traumatic brain injury: a population-based study
- (2012) Kristen Dams-O'Connor et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
- (2012) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging
- (2012) J. Vukovic et al. JOURNAL OF NEUROSCIENCE
- Genomic Analysis of Reactive Astrogliosis
- (2012) J. L. Zamanian et al. JOURNAL OF NEUROSCIENCE
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Gut microbiota composition correlates with diet and health in the elderly
- (2012) Marcus J. Claesson et al. NATURE
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Postprandial apoE Isoform and Conformational Changes Associated with VLDL Lipolysis Products Modulate Monocyte Inflammation
- (2012) Laura J. den Hartigh et al. PLoS One
- Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains
- (2012) Celeste M. Karch et al. PLoS One
- Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery
- (2012) K. Hayakawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CXCR4 Antagonist AMD3100 Protects Blood–Brain Barrier Integrity and Reduces Inflammatory Response After Focal Ischemia in Mice
- (2012) Jun Huang et al. STROKE
- Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice
- (2011) Michael Sy et al. AMERICAN JOURNAL OF PATHOLOGY
- PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
- (2011) Tamas Varga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Widespread Tau and Amyloid-Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans
- (2011) Victoria E. Johnson et al. BRAIN PATHOLOGY
- Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1 Transcription in Human Adipose Tissue
- (2011) T. B. Koenen et al. DIABETES
- TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
- (2011) Hiroaki Ito et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Lipopolysaccharide-induced tau phosphorylation and kinase activity - modulation, but not mediation, by corticotropin-releasing factor receptors
- (2011) Allyson D. Roe et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- TLR2 Is a Primary Receptor for Alzheimer's Amyloid Peptide To Trigger Neuroinflammatory Activation
- (2011) S. Liu et al. JOURNAL OF IMMUNOLOGY
- Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal -Catenin Pathway Function in an Alzheimer's Disease Model
- (2011) M. Kitazawa et al. JOURNAL OF IMMUNOLOGY
- Critical Role of Astroglial Apolipoprotein E and Liver X Receptor- Expression for Microglial A Phagocytosis
- (2011) D. Terwel et al. JOURNAL OF NEUROSCIENCE
- The Association between Apolipoprotein E and Traumatic Brain Injury Severity and Functional Outcome in a Rehabilitation Sample
- (2011) Jennie Ponsford et al. JOURNAL OF NEUROTRAUMA
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
- (2011) Adam C Naj et al. NATURE GENETICS
- Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
- (2011) Karim Belarbi et al. NEUROBIOLOGY OF DISEASE
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
- (2011) J. I. Alvarez et al. SCIENCE
- CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models
- (2010) Sungho Lee et al. AMERICAN JOURNAL OF PATHOLOGY
- Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors
- (2010) Mohan R. Dasu et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The role of TNF-α signaling pathway on COX-2 upregulation and cognitive decline induced by β-amyloid peptide
- (2010) Rodrigo Medeiros et al. BEHAVIOURAL BRAIN RESEARCH
- Amelioration of the Alzheimer's Disease Phenotype by Absence of 12/15-Lipoxygenase
- (2010) Hengxuan Yang et al. BIOLOGICAL PSYCHIATRY
- Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme
- (2010) Min Ren et al. EMBO JOURNAL
- Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways
- (2010) Roser Gorina et al. GLIA
- Bacterial infection causes stress-induced memory dysfunction in mice
- (2010) M. G. Gareau et al. GUT
- Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice
- (2010) Bridgette D Semple et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
- (2010) Daniel C Lee et al. Journal of Neuroinflammation
- CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid- Phagocytosis
- (2010) Z. Liu et al. JOURNAL OF NEUROSCIENCE
- Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme
- (2010) Y. Kong et al. JOURNAL OF NEUROSCIENCE
- Vasopressin Amplifies the Production of Proinflammatory Mediators in Traumatic Brain Injury
- (2010) Joanna Szmydynger-Chodobska et al. JOURNAL OF NEUROTRAUMA
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
- (2010) eMalick G. Njie et al. NEUROBIOLOGY OF AGING
- Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury
- (2010) Bridgette D. Semple et al. NEUROBIOLOGY OF DISEASE
- Regulation of Tau Pathology by the Microglial Fractalkine Receptor
- (2010) Kiran Bhaskar et al. NEURON
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide
- (2010) Stephanie J. Soscia et al. PLoS One
- Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians
- (2010) Elena Biagi et al. PLoS One
- Composition, variability, and temporal stability of the intestinal microbiota of the elderly
- (2010) M. J. Claesson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MHC class I modulates NMDA receptor function and AMPA receptor trafficking
- (2010) L. Fourgeaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke
- (2010) Giorgio Luciano Viviani et al. THROMBOSIS AND HAEMOSTASIS
- Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease
- (2009) Wolfgang J. Streit et al. ACTA NEUROPATHOLOGICA
- FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1 Production in Macrophages
- (2009) D. Su et al. DIABETES
- Accumulation of tau induced in neurites by microglial proinflammatory mediators
- (2009) Philipp Gorlovoy et al. FASEB JOURNAL
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
- (2009) Stefan A Grathwohl et al. NATURE NEUROSCIENCE
- VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
- (2009) Azeb Tadesse Argaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE
- (2008) Lars Bertram et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Inflammation induces tau pathology in inclusion body myositis model via glycogen synthase kinase-3β
- (2008) Masashi Kitazawa et al. ANNALS OF NEUROLOGY
- Minocycline reduces the development of abnormal tau species in models of Alzheimer’s disease
- (2008) Wendy Noble et al. FASEB JOURNAL
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- APOE genotype-specific differences in the innate immune response
- (2007) Michael P. Vitek et al. NEUROBIOLOGY OF AGING
- Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: Inverse correlation with Aβ levels
- (2006) E. Hellström-Lindahl et al. NEUROBIOLOGY OF AGING
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now