Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response

Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice

(2017) Ho Tsoi et al.   GASTROENTEROLOGY

The pro-inflammatory cytokine TNF-α inhibits lymphatic pumping via activation of the NF-κB-iNOS signaling pathway

(2017) Yingxuan Chen et al.   MICROCIRCULATION

Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle?

(2017) S.M. O’Mahony et al.   NEUROSCIENCE

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

The short-lived African turquoise killifish: an emerging experimental model for ageing

(2016) Yumi Kim et al.   Disease Models & Mechanisms

Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis

(2016) Marlies Meisel et al.   ISME Journal

Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling

(2016) Nicholas Edward Ilott et al.   ISME Journal

Germ-free and Antibiotic-treated Mice are Highly Susceptible to Epithelial Injury in DSS Colitis

(2016) Cristina Hernández-Chirlaque et al.   Journal of Crohns & Colitis

Increased Enterococcus faecalis infection is associated with clinically active Crohn disease

(2016) Youlian Zhou et al.   MEDICINE

Fecal microbiota transplantation in inflammatory bowel disease: the quest for the holy grail

(2016) B Pigneur et al.   Mucosal Immunology

Epidemiology: Rising in the East

(2016) Kelly Rae Chi   NATURE

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

(2016) Caroline P. Le et al.   Nature Communications

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

(2015) Si Ming Man et al.   CELL

Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome

(2015) Rachel D. Moloney et al.   CNS Neuroscience & Therapeutics

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

(2015) Katerina Vlantis et al.   GUT

Enterohepatic Helicobacter Species as a Potential Causative Factor in Inflammatory Bowel Disease

(2015) Qiao Yu et al.   MEDICINE

Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2

(2015) E R Cobo et al.   Mucosal Immunology

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon

(2015) Noortje Ijssennagger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

(2015) M. Vetizou et al.   SCIENCE

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

(2014) Markus Tschurtschenthaler et al.   GUT

Interleukin-6, but not the interleukin-6 receptor plays a role in recovery from dextran sodium sulfate-induced colitis

(2014) JAN SOMMER et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens

(2014) S. M. Dann et al.   JOURNAL OF IMMUNOLOGY

Spontaneous Colitis in Muc2-Deficient Mice Reflects Clinical and Cellular Features of Active Ulcerative Colitis

(2014) Ulf A. Wenzel et al.   PLoS One

Inflammatory bowel disease: Pathogenesis

(2014) Yi-Zhen Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

(2013) Phillipp Hartmann et al.   HEPATOLOGY

The Promise of Poop

(2013) J. de Vrieze   SCIENCE

Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling

(2012) Donald M. Lamkin et al.   BRAIN BEHAVIOR AND IMMUNITY

IL-10 Promotes Production of Intestinal Mucus by Suppressing Protein Misfolding and Endoplasmic Reticulum Stress in Goblet Cells

(2012) Sumaira Z. Hasnain et al.   GASTROENTEROLOGY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Gut microbiome composition is linked to whole grain-induced immunological improvements

(2012) Inés Martínez et al.   ISME Journal

Defective IL10 Signaling Defining a Subgroup of Patients With Inflammatory Bowel Disease

(2011) Bernadette Begue et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Role of the lymphatic system in the pathogenesis of Crohnʼs disease

(2011) Pierre-Yves von der Weid et al.   CURRENT OPINION IN GASTROENTEROLOGY

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Hen Egg Lysozyme Attenuates Inflammation and Modulates Local Gene Expression in a Porcine Model of Dextran Sodium Sulfate (DSS)-Induced Colitis

(2009) Maggie Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis: Potential Role of Chronic Inflammation

(2008) K. Yang et al.   CANCER RESEARCH

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA