Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
出版年份 2014 全文链接
标题
Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
作者
关键词
-
出版物
NEUROPSYCHOPHARMACOLOGY
Volume 39, Issue 13, Pages 2949-2962
出版商
Springer Nature
发表日期
2014-07-22
DOI
10.1038/npp.2014.164
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease
- (2014) Teng Jiang et al. PHARMACOLOGICAL RESEARCH
- Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12
- (2013) Agnieszka Paradowska-Gorycka et al. HUMAN IMMUNOLOGY
- TREM2 in Alzheimer’s disease
- (2013) Teng Jiang et al. MOLECULAR NEUROBIOLOGY
- Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice
- (2013) Teng Jiang et al. NEUROBIOLOGY OF AGING
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- Smoking exacerbates amyloid pathology in a mouse model of Alzheimer’s disease
- (2013) Ines Moreno-Gonzalez et al. Nature Communications
- An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A Binding Properties Promotes Neuroprotection and Glial Engulfment of A
- (2012) O. Adolfsson et al. JOURNAL OF NEUROSCIENCE
- Variant TREM2 as Risk Factor for Alzheimer's Disease
- (2012) Harald Neumann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
- (2011) Hiroaki Ito et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- TLR2 Is a Primary Receptor for Alzheimer's Amyloid Peptide To Trigger Neuroinflammatory Activation
- (2011) S. Liu et al. JOURNAL OF IMMUNOLOGY
- Soluble Aβ oligomer production and toxicity
- (2011) Megan E. Larson et al. JOURNAL OF NEUROCHEMISTRY
- Autoimmune and inflammatory mechanisms of CNS damage
- (2011) Minesh Kapadia et al. PROGRESS IN NEUROBIOLOGY
- Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
- (2010) Gunnar K. Gouras et al. ACTA NEUROPATHOLOGICA
- Dual Induction of TREM2 and Tolerance-Related Transcript, Tmem176b, in Amyloid Transgenic Mice: Implications for Vaccine-Based Therapies for Alzheimer's Disease
- (2010) Benoit Melchior et al. ASN Neuro
- NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
- (2009) Nicholas H. Varvel et al. JOURNAL OF CLINICAL INVESTIGATION
- A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
- (2009) Christine L. Hsieh et al. JOURNAL OF NEUROCHEMISTRY
- TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
- (2008) Stefanie Frank et al. GLIA
- Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
- (2008) Jing-Ji Jin et al. Journal of Neuroinflammation
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