Secreted Hsp90 Is a Novel Regulator of the Epithelial to Mesenchymal Transition (EMT) in Prostate Cancer
出版年份 2012 全文链接
标题
Secreted Hsp90 Is a Novel Regulator of the Epithelial to Mesenchymal Transition (EMT) in Prostate Cancer
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 45, Pages 37732-37744
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2012-09-19
DOI
10.1074/jbc.m112.389015
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer statistics, 2012
- (2012) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Abstract 2917: Design, synthesis and biological evaluation of two chemical classes as novel small molecule Mcl-1 inhibitors
- (2012) Naval Bajwa et al. CANCER RESEARCH
- Matrix Metalloproteinase (MMP)-3 Activates MMP-9 Mediated Vascular Smooth Muscle Cell Migration and Neointima Formation in Mice
- (2011) Jason L. Johnson et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- 2-Microglobulin Induces Epithelial to Mesenchymal Transition and Confers Cancer Lethality and Bone Metastasis in Human Cancer Cells
- (2011) S. Josson et al. CANCER RESEARCH
- Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
- (2011) Y. Sun et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- A potentially common peptide target in secreted heat shock protein-90α for hypoxia-inducible factor-1α–positive tumors
- (2011) Divya Sahu et al. MOLECULAR BIOLOGY OF THE CELL
- IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR
- (2011) A Rojas et al. ONCOGENE
- A Novel Extracellular Hsp90 Mediated Co-Receptor Function for LRP1 Regulates EphA2 Dependent Glioblastoma Cell Invasion
- (2011) Udhayakumar Gopal et al. PLoS One
- Extracellular Heat Shock Protein (Hsp)70 and Hsp90α Assist in Matrix Metalloproteinase-2 Activation and Breast Cancer Cell Migration and Invasion
- (2011) Jessica D. Sims et al. PLoS One
- LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling
- (2011) Hui-Wen Lue et al. PLoS One
- Molecular classification of prostate cancer using curated expression signatures
- (2011) E. K. Markert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits
- (2010) Dimitris Stellas et al. BMC CELL BIOLOGY
- ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading
- (2010) Paul Mak et al. CANCER CELL
- Matrix Metalloproteinase-9 Is Upregulated in Nucleophosmin-Anaplastic Lymphoma Kinase-Positive Anaplastic Lymphomas and Activated at the Cell Surface by the Chaperone Heat Shock Protein 90 to Promote Cell Invasion
- (2010) F. Lagarrigue et al. CANCER RESEARCH
- A New Therapy Paradigm for Prostate Cancer Founded on Clinical Observations
- (2010) E. Efstathiou et al. CLINICAL CANCER RESEARCH
- A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration
- (2010) G. A. Smolen et al. GENES & DEVELOPMENT
- The Regulatory Mechanism of Extracellular Hsp90α on Matrix Metalloproteinase-2 Processing and Tumor Angiogenesis
- (2010) Xiaomin Song et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Promotion of hepatocellular carcinoma metastasis through matrix metalloproteinase activation by epithelial-mesenchymal transition regulator Twist1
- (2010) Xiu-lan Zhao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Loss of PDEF, a prostate-derived Ets factor is associated with aggressive phenotype of prostate cancer: Regulation of MMP 9 by PDEF
- (2010) Thomas R Johnson et al. Molecular Cancer
- ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events
- (2010) Sejeong Shin et al. MOLECULAR CELL
- Recognition of a signal peptide by the signal recognition particle
- (2010) Claudia Y. Janda et al. NATURE
- Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
- (2010) Hiroshi Tanaka et al. NATURE MEDICINE
- Prostate cancer screening: current status and future perspectives
- (2010) Seth A. Strope et al. Nature Reviews Urology
- LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways
- (2010) Benoit Langlois et al. PLoS One
- Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
- (2010) D. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phorbol ester phorbol-12-myristate-13-acetate induces epithelial to mesenchymal transition in human prostate cancer ARCaPE cells
- (2010) Hui He et al. PROSTATE
- Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV
- (2010) Zhiqiang Qin et al. VIROLOGY
- Hsp90 as a Gatekeeper of Tumor Angiogenesis: Clinical Promise and Potential Pitfalls
- (2010) J. E. Bohonowych et al. Journal of Oncology
- The effect of obesity and lower serum prostate-specific antigen levels on prostate-cancer screening results in American men
- (2009) Stephen Culp et al. BJU INTERNATIONAL
- Cancer Statistics, 2009
- (2009) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Nuclear Factor- B-Mediated Transforming Growth Factor- -Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy
- (2009) Q. Zhang et al. CLINICAL CANCER RESEARCH
- Inhibition of vimentin or 1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo
- (2009) X. Zhang et al. MOLECULAR CANCER THERAPEUTICS
- RSK Is a Principal Effector of the RAS-ERK Pathway for Eliciting a Coordinate Promotile/Invasive Gene Program and Phenotype in Epithelial Cells
- (2009) Ulrik Doehn et al. MOLECULAR CELL
- The lottery of conventional prostate biopsy
- (2009) Gerald L. Andriole Nature Reviews Urology
- The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy
- (2009) Xiaofeng Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ligand Binding to LRP1 Transactivates Trk Receptors by a Src Family Kinase-Dependent Pathway
- (2009) Y. Shi et al. Science Signaling
- The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition markers, E-cadherin and β-catenin, in prostate cancer
- (2009) Hector R. Contreras et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Understanding the Epidemiology, Natural History, and Key Pathways Involved in Prostate Cancer
- (2009) E. David Crawford UROLOGY
- Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells
- (2008) C. Figueiredo et al. BLOOD
- Role of Acetylation and Extracellular Location of Heat Shock Protein 90 in Tumor Cell Invasion
- (2008) Y. Yang et al. CANCER RESEARCH
- Loss of E-Cadherin Promotes Metastasis via Multiple Downstream Transcriptional Pathways
- (2008) T. T. Onder et al. CANCER RESEARCH
- Insulin-like Growth Factor-I-Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells
- (2008) T. R. Graham et al. CANCER RESEARCH
- Epithelial to mesenchymal transition (EMT) in human prostate cancer: lessons learned from ARCaP model
- (2008) Haiyen E. Zhau et al. CLINICAL & EXPERIMENTAL METASTASIS
- The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein
- (2008) E. Mantuano et al. JOURNAL OF NEUROSCIENCE
- Transforming Growth Factor (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing
- (2008) C.-F. Cheng et al. MOLECULAR AND CELLULAR BIOLOGY
- Transforming Growth Factor- 1 Promotes Matrix Metalloproteinase-9-Mediated Oral Cancer Invasion through Snail Expression
- (2008) L. Sun et al. MOLECULAR CANCER RESEARCH
- Prostate cancer serum biomarker discovery through proteomic analysis of alpha-2 macroglobulin protein complexes
- (2008) Earle F. Burgess et al. Proteomics Clinical Applications
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