The interplay of extracellular matrix and microbiome in urothelial bladder cancer

Malignancy of bladder cancer cells is enhanced by tumor-associated fibroblasts through a multifaceted cytokine-chemokine loop

(2015) Susanne Grimm et al.   EXPERIMENTAL CELL RESEARCH

Tenascin-C and carcinoma cell invasion in oral and urinary bladder cancer

(2015) Alexander Berndt et al.   Cell Adhesion & Migration

Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo

(2015) Orsolya Kiraly et al.   PLoS Genetics

Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors

(2014) Ge Zhang et al.   BMC CANCER

Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer

(2014) X Wang et al.   BRITISH JOURNAL OF CANCER

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation

(2014) Franco Klingberg et al.   JOURNAL OF CELL BIOLOGY

Post-translational modifications of integrin ligands as pathogenic mechanisms in disease

(2014) Cédric Zeltz et al.   MATRIX BIOLOGY

Peyronie's disease: Review and recent advances

(2014) Joshua P. Langston et al.   MATURITAS

The Multifaceted Role of the Intestinal Microbiota in Colon Cancer

(2014) Thergiory Irrazábal et al.   MOLECULAR CELL

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Optimizing intravesical mitomycin C therapy in non-muscle-invasive bladder cancer

(2014) Homayoun Zargar et al.   Nature Reviews Urology

The mechanism of action of BCG therapy for bladder cancer—a current perspective

(2014) Gil Redelman-Sidi et al.   Nature Reviews Urology

Cellular Localization, Invasion, and Turnover Are Differently Influenced by Healthy and Tumor-Derived Extracellular Matrix

(2014) Luca Genovese et al.   TISSUE ENGINEERING PART A

Molecular markers for urothelial bladder cancer prognosis: Toward implementation in clinical practice

(2014) Bas W.G. van Rhijn et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Considerations on the use of urine markers in the management of patients with high-grade non–muscle-invasive bladder cancer

(2014) Ashish M. Kamat et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Colorectal cancer in inflammatory bowel disease: The risk, pathogenesis, prevention and diagnosis

(2014) Eun Ran Kim   WORLD JOURNAL OF GASTROENTEROLOGY

American Journal of Gastroenterology Lecture: Intestinal Microbiota and the Role of Fecal Microbiota Transplant (FMT) in Treatment of C. difficile Infection

(2013) Lawrence J Brandt   AMERICAN JOURNAL OF GASTROENTEROLOGY

Diet Complexity and Estrogen Receptor β Status Affect the Composition of the Murine Intestinal Microbiota

(2013) Rani Menon et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Direct detection of hyaluronidase in urine using cationic gold nanoparticles: A potential diagnostic test for bladder cancer

(2013) Ahmed Ibrahim Nossier et al.   BIOSENSORS & BIOELECTRONICS

Implications of the human microbiome in inflammatory bowel diseases

(2013) Syeda M. Bakhtiar et al.   FEMS MICROBIOLOGY LETTERS

Enhanced stromal syndecan-1 expression is an independent risk factor for poor survival in bladder cancer

(2013) Tibor Szarvas et al.   HUMAN PATHOLOGY

Group A Streptococcal Cysteine Protease Cleaves Epithelial Junctions and Contributes to Bacterial Translocation

(2013) Tomoko Sumitomo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of the Proteolytic Activities of New Commercially Available Bacterial and Fungal Proteases toward Meat Proteins

(2013) Minh Ha et al.   JOURNAL OF FOOD SCIENCE

Dysbiosis Signature of Fecal Microbiota in Colorectal Cancer Patients

(2013) Na Wu et al.   MICROBIAL ECOLOGY

Fecal Microbiota Transplantation — An Old Therapy Comes of Age

(2013) Ciarán P. Kelly   NEW ENGLAND JOURNAL OF MEDICINE

Suppression and Activation of the Malignant Phenotype by Extracellular Matrix in Xenograft Models of Bladder Cancer: A Model for Tumor Cell “Dormancy”

(2013) Robert E. Hurst et al.   PLoS One

The Impact of the Receptor of Hyaluronan-Mediated Motility (RHAMM) on Human Urothelial Transitional Cell Cancer of the Bladder

(2013) Christian Niedworok et al.   PLoS One

Inhibitory Role of the Small Leucine-Rich Proteoglycan Biglycan in Bladder Cancer

(2013) Christian Niedworok et al.   PLoS One

Lack of Decorin Expression by Human Bladder Cancer Cells Offers New Tools in the Therapy of Urothelial Malignancies

(2013) Annele Sainio et al.   PLoS One

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

Bladder Acellular Matrix and Its Application in Bladder Augmentation

(2013) Lujie Song et al.   TISSUE ENGINEERING PART B-REVIEWS

Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)

(2013) Katarzyna J. Maresz et al.   PLoS Pathogens

The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults

(2013) Debbie A. Lewis et al.   Frontiers in Cellular and Infection Microbiology

Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ

(2013) Caitriona M. Guinane et al.   Therapeutic Advances in Gastroenterology

The Biomechanical Effect of Corneal Collagen Cross-Linking (CXL) With Riboflavin and UV-A is Oxygen Dependent

(2013) Olivier Richoz et al.   Translational Vision Science & Technology

The Microbiome and Inflammatory Bowel Disease: Is There a Therapeutic Role for Fecal Microbiota Transplantation?

(2012) Christopher J Damman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Proteolytic Activity by Multiple Bacterial Species Isolated From Chronic Venous Leg Ulcers Degrades Matrix Substrates

(2012) A. B. Wysocki et al.   Biological Research for Nursing

Bacterial invasion factors: Tools for crossing biological barriers and drug delivery?

(2012) Annika Kochut et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Targeting embryonic signaling pathways in cancer therapy

(2012) Pamela Jo Harris et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans

(2012) Nina Sanapareddy et al.   ISME Journal

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury

(2012) Derrick E Fouts et al.   Journal of Translational Medicine

Reciprocal interactions of the intestinal microbiota and immune system

(2012) Craig L. Maynard et al.   NATURE

Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer

(2012) Weiguang Chen et al.   PLoS One

Arresten, a Collagen-Derived Angiogenesis Inhibitor, Suppresses Invasion of Squamous Cell Carcinoma

(2012) Mari Aikio et al.   PLoS One

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

(2012) C. P. El-Haibi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer

(2012) Weiwei Shi et al.   TUMOR BIOLOGY

Biglycan expression and clinical outcome in patients with pancreatic adenocarcinoma

(2012) Giuseppe Aprile et al.   TUMOR BIOLOGY

The role of endogenous and exogenous enzymes in chronic wounds: A focus on the implications of aberrant levels of both host and bacterial proteases in wound healing

(2012) Sara M. McCarty et al.   WOUND REPAIR AND REGENERATION

Inhibition of Protein Kinase C AttenuatesPseudomonas aeruginosaElastase–Induced Epithelial Barrier Disruption

(2011) Curtis A. Clark et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Assessing diversity of the female urine microbiota by high throughput sequencing of 16S rDNA amplicons

(2011) Huma Siddiqui et al.   BMC MICROBIOLOGY

Biglycan expression correlates with aggressiveness and poor prognosis of gastric cancer

(2011) Bin Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats

(2011) Martin Novotný et al.   EXPERIMENTAL DERMATOLOGY

Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation

(2011) Natalie Steck et al.   GASTROENTEROLOGY

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: Impact of a “Top-Down” approach to intestinal fibrosis in mice

(2011) Laura A. Johnson et al.   INFLAMMATORY BOWEL DISEASES

Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis

(2011) Jeon Hwang-Bo et al.   INTERNATIONAL JOURNAL OF CANCER

Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers

(2011) Tingting Wang et al.   ISME Journal

Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

(2011) Renato V. Iozzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer

(2011) Ann-Marie Baker et al.   JNCI-Journal of the National Cancer Institute

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Asymptomatic bacteriuria: when the treatment is worse than the disease

(2011) Barbara W. Trautner   Nature Reviews Urology

Molecular biomarkers in urothelial carcinoma of the bladder: are we there yet?

(2011) George J. Netto   Nature Reviews Urology

Matrix metalloproteinases and their clinical relevance in urinary bladder cancer

(2011) Tibor Szarvas et al.   Nature Reviews Urology

Hyaluronan as an Immune Regulator in Human Diseases

(2011) Dianhua Jiang et al.   PHYSIOLOGICAL REVIEWS

Microbial Dysbiosis in Colorectal Cancer (CRC) Patients

(2011) Iradj Sobhani et al.   PLoS One

Intestinal Microbiota in Healthy Adults: Temporal Analysis Reveals Individual and Common Core and Relation to Intestinal Symptoms

(2011) Jonna Jalanka-Tuovinen et al.   PLoS One

Genetic Control of the Variable Innate Immune Response to Asymptomatic Bacteriuria

(2011) Jenny Grönberg Hernández et al.   PLoS One

Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions

(2011) R. O. Hynes et al.   Cold Spring Harbor Perspectives in Biology

Fibronectins, Their Fibrillogenesis, and In Vivo Functions

(2011) J. E. Schwarzbauer et al.   Cold Spring Harbor Perspectives in Biology

Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer

(2010) Tibor Szarvas et al.   CANCER SCIENCE

Post-translational modifications in host cells during bacterial infection

(2010) David Ribet et al.   FEBS LETTERS

Degradation of the extracellular matrix components by bacterial-derived metalloproteases

(2010) Mihaela Pruteanu et al.   INFLAMMATORY BOWEL DISEASES

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

(2010) Kristin Moreth et al.   JOURNAL OF CLINICAL INVESTIGATION

Serine proteases of the human immune system in health and disease

(2010) Kirstin M. Heutinck et al.   MOLECULAR IMMUNOLOGY

Galectin-3 expression is associated with bladder cancer progression and clinical outcome

(2010) Giacomo Canesin et al.   TUMOR BIOLOGY

Mammalian Target of Rapamycin (mTOR) Induces Proliferation and De-Differentiation Responses to Three Coordinate Pathophysiologic Stimuli (Mechanical Strain, Hypoxia, and Extracellular Matrix Remodeling) in Rat Bladder Smooth Muscle

(2009) Karen J. Aitken et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial–Mesenchymal Transition: From Molecular Mechanisms, Redox Regulation to Implications in Human Health and Disease

(2009) Stefania Cannito et al.   ANTIOXIDANTS & REDOX SIGNALING

Type IV collagen is a tumour stroma-derived biomarker for pancreas cancer

(2009) D Öhlund et al.   BRITISH JOURNAL OF CANCER

HYAL-1 Hyaluronidase: A Potential Prognostic Indicator for Progression to Muscle Invasion and Recurrence in Bladder Cancer

(2009) Mario W. Kramer et al.   EUROPEAN UROLOGY

Immunohistochemical detection of advanced glycation end products in human bladder with specific monoclonal antibody

(2009) Kenshi Matsumoto et al.   INTERNATIONAL JOURNAL OF UROLOGY

The bladder extracellular matrix. Part II: regenerative applications

(2009) Karen J. Aitken et al.   Nature Reviews Urology

The bladder extracellular matrix. Part I: architecture, development and disease

(2009) Karen J. Aitken et al.   Nature Reviews Urology

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

(2009) Catherine E Forristal et al.   REPRODUCTION

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Cancer Stem Cells, Hypoxia and Metastasis

(2009) Richard P. Hill et al.   SEMINARS IN RADIATION ONCOLOGY

Nidogen-1 and nidogen-2 in healthy human cartilage and in late-stage osteoarthritis cartilage

(2008) Jenny Kruegel et al.   ARTHRITIS AND RHEUMATISM

Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

(2008) Karl E Kadler et al.   CURRENT OPINION IN CELL BIOLOGY

Activation of Hypoxic Response in Human Embryonic Stem Cell–Derived Embryoid Bodies

(2008) C. M. Cameron et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

A component of polysaccharide peptidoglycan complex onLactobacillusinduced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer

(2008) S. Matsumoto et al.   IMMUNOLOGY

Prevention of Recurrence With Epirubicin and Lactobacillus Casei After Transurethral Resection of Bladder Cancer

(2008) Seiji Naito et al.   JOURNAL OF UROLOGY

Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage

(2008) William C. Little et al.   MATRIX BIOLOGY

Novel interactions of perlecan: Unraveling perlecan's role in angiogenesis

(2008) Gregory Bix et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction

(2008) Michael A Fox et al.   Neural Development

Mechanical strain activates a program of genes functionally involved in paracrine signaling of angiogenesis

(2008) Ru Yang et al.   PHYSIOLOGICAL GENOMICS

Fibronectin Unfolding Revisited: Modeling Cell Traction-Mediated Unfolding of the Tenth Type-III Repeat

(2008) Elaine P. S. Gee et al.   PLoS One