Integrating mechanisms of pulmonary fibrosis

Th17-Polarized Immune Response in a Murine Model of Hypersensitivity Pneumonitis and Lung Fibrosis

(2014) P. L. Simonian et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

 -Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix

(2011) A. K. Lovgren et al.   Science Translational Medicine

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

(2010) Kusum V. Pandit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension

(2010) Eileen Hsu et al.   ARTHRITIS AND RHEUMATISM

Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease

(2010) M. Brodlie et al.   EUROPEAN RESPIRATORY JOURNAL

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

(2010) Dianhua Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice

(2010) Kristy A. Bauman et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

(2010) Mark S. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

γδ T cells protect against lung fibrosis via IL-22

(2010) Philip L. Simonian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13-Dependent Fibrosis

(2010) S. K. Madala et al.   JOURNAL OF IMMUNOLOGY

Repression of IP-10 by Interactions between Histone Deacetylation and Hypermethylation in Idiopathic Pulmonary Fibrosis

(2010) W. R. Coward et al.   MOLECULAR AND CELLULAR BIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Methylation determines fibroblast activation and fibrogenesis in the kidney

(2010) Wibke Bechtel et al.   NATURE MEDICINE

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2

(2010) Patrick J. Lupardus et al.   STRUCTURE

Serum CC-Chemokine Ligand 18 Concentration Predicts Outcome in Idiopathic Pulmonary Fibrosis

(2009) Antje Prasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis

(2009) Pamela Gasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages

(2009) Kamran Atabai et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 Induces IL-13-Dependent Cutaneous Fibrosis

(2009) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin

(2009) Thirumalai R. Ramalingam et al.   JOURNAL OF IMMUNOLOGY

Interleukin-13 and Its Receptors in Idiopathic Interstitial Pneumonia: Clinical Implications for Lung Function

(2009) Sung-Woo Park et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Prostaglandin F2α receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-β

(2009) Toru Oga et al.   NATURE MEDICINE

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Pulmonary complications of tumor necrosis factor-targeted therapy

(2009) Krishna Thavarajah et al.   RESPIRATORY MEDICINE

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Treatment of Idiopathic Pulmonary Fibrosis with Etanercept

(2008) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Integrating the MicroRNome into the Study of Lung Disease

(2008) Serge P. Nana-Sinkam et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Thy-1 Promoter Hypermethylation

(2008) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

(2008) Shuomin Zhu et al.   CELL RESEARCH

Mechanisms of Fibrogenesis

(2008) Tatiana Kisseleva et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2

(2008) Lynne A. Murray et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Epithelial cell α3β1 integrin links β-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis

(2008) Kevin K. Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

(2008) Hong Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation

(2008) D. D. Shao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

(2008) Melanie Königshoff et al.   PLoS One

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

(2008) Robert W. Thompson et al.   PLoS Pathogens

PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis

(2007) Jami E. Milam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oxidative Stress, Plasminogen Activator Inhibitor 1, and Lung Fibrosis

(2007) Rui-Ming Liu   ANTIOXIDANTS & REDOX SIGNALING

The Role of Inflammation in the Pathogenesis of Idiopathic Pulmonary Fibrosis

(2007) Benjamin D. Bringardner et al.   ANTIOXIDANTS & REDOX SIGNALING

Baseline BAL Neutrophilia Predicts Early Mortality in Idiopathic Pulmonary Fibrosis

(2007) Brent W. Kinder et al.   CHEST