Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo

DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo

(2014) O. Kiraly et al.   CARCINOGENESIS

A Nanoparticle-Based Combination Chemotherapy Delivery System for Enhanced Tumor Killing by Dynamic Rewiring of Signaling Pathways

(2014) S. W. Morton et al.   Science Signaling

Breast Cancer Proteins PALB2 and BRCA2 Stimulate Polymerase η in Recombination-Associated DNA Synthesis at Blocked Replication Forks

(2014) Rémi Buisson et al.   Cell Reports

Pancreatic cancer risk in hereditary pancreatitis

(2014) Frank U. Weiss   Frontiers in Physiology

Do mutator mutations fuel tumorigenesis?

(2013) Edward J. Fox et al.   CANCER AND METASTASIS REVIEWS

Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans

(2013) Marek Sebesta et al.   DNA REPAIR

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

(2013) Lorenzo Costantino et al.   SCIENCE

Has the risk of colorectal cancer in inflammatory bowel disease decreased?

(2013) Nynne Nyboe Andersen   WORLD JOURNAL OF GASTROENTEROLOGY

The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers

(2012) J Iqbal et al.   BRITISH JOURNAL OF CANCER

Oxidatively induced DNA damage: Mechanisms, repair and disease

(2012) Miral Dizdaroglu   CANCER LETTERS

p53 null Fluorescent Yellow Direct Repeat (FYDR) mice have normal levels of homologous recombination

(2011) Dominika M. Wiktor-Brown et al.   DNA REPAIR

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

(2011) Valerie Garcia et al.   NATURE

REV1 and polymerase ζ facilitate homologous recombination repair

(2011) Shilpy Sharma et al.   NUCLEIC ACIDS RESEARCH

Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

(2011) J Pal et al.   ONCOGENE

Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer

(2010) Ferdinandos Skoulidis et al.   CANCER CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates

(2010) Pallavi Lonkar et al.   INTERNATIONAL JOURNAL OF CANCER

Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks

(2010) Matthew L Nicolette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

(2010) M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection

(2010) A. Sheh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Error-prone translesion synthesis mediates acquired chemoresistance

(2010) K. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Mutagenesis and Unique Mutation Signature Associated with Mitotic Gene Conversion

(2010) W. M. Hicks et al.   SCIENCE

Role of MUTYH and MSH2 in the Control of Oxidative DNA Damage, Genetic Instability, and Tumorigenesis

(2009) M. T. Russo et al.   CANCER RESEARCH

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases   and  

(2009) S. D. McCulloch et al.   NUCLEIC ACIDS RESEARCH

Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice

(2009) Lisiane B. Meira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load

(2008) D. M. Wiktor-Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA