Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer

Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling

(2014) Sherif A. Ibrahim et al.   PLoS One

Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes

(2013) George Pentheroudakis et al.   BMC CANCER

Syndecan-1 and Heparanase

(2013) Shaoheng Zhang et al.   INFLAMMATORY BOWEL DISEASES

Chemotherapy stimulates syndecan-1 shedding: A potentially negative effect of treatment that may promote tumor relapse

(2013) Vishnu C. Ramani et al.   MATRIX BIOLOGY

Molecular functions of syndecan-1 in disease

(2011) Yvonne Hui-Fang Teng et al.   MATRIX BIOLOGY

EGFR-mediated G1/S transition contributes to the multidrug resistance in breast cancer cells

(2011) Shu-Jun Chen et al.   MOLECULAR BIOLOGY REPORTS

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis

(2010) A. Purushothaman et al.   BLOOD

Activated Syndecan-1 Shedding Contributes to Mice Colitis Induced by Dextran Sulfate Sodium

(2010) Xia Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression

(2009) Viktoriya Nikolova et al.   CARCINOGENESIS

Proteoglycan signaling co-receptors: Roles in cell adhesion, migration and invasion

(2009) Karthikeyan Mythreye et al.   CELLULAR SIGNALLING

A Disintegrin and Metalloproteinase 17 (ADAM17) Mediates Inflammation-induced Shedding of Syndecan-1 and -4 by Lung Epithelial Cells

(2009) Jessica Pruessmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MMP7 Shedding of Syndecan-1 Facilitates Re-Epithelialization by Affecting α2β1 Integrin Activation

(2009) Peter Chen et al.   PLoS One

Association of loss of epithelial syndecan-1 with stage and local metastasis of colorectal adenocarcinomas: An immunohistochemical study of clinically annotated tumors

(2008) Yosuke Hashimoto et al.   BMC CANCER

Membrane Type 1 Matrix Metalloproteinase-Mediated Stromal Syndecan-1 Shedding Stimulates Breast Carcinoma Cell Proliferation

(2008) G. Su et al.   CANCER RESEARCH

Syndecan-1 Ectodomain Shedding Is Regulated by the Small GTPase Rab5

(2008) Kazutaka Hayashida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY