Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells

Effects of functional olive oil enriched with its own phenolic compounds on endothelial function in hypertensive patients. A randomised controlled trial

(2015) Rosa-M. Valls et al.   FOOD CHEMISTRY

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

(2014) Marta Guasch-Ferré et al.   BMC Medicine

Metabolite profiling of olive oil and thyme phenols after a sustained intake of two phenol-enriched olive oils by humans: Identification of compliance markers

(2014) Laura Rubió et al.   FOOD RESEARCH INTERNATIONAL

Hydroxytyrosol and Its Potential Therapeutic Effects

(2014) Ting Hu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Effects of the Mediterranean Diet on Biomarkers of Vascular Wall Inflammation and Plaque Vulnerability in Subjects with High Risk for Cardiovascular Disease. A Randomized Trial

(2014) Rosa Casas et al.   PLoS One

Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1

(2014) Carolina Emilia Storniolo et al.   Redox Biology

Anti-Inflammatory Effects of Danshen on Human Vascular Endothelial Cells in Culture

(2013) Christian Stumpf et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Effect of the co-occurring olive oil and thyme extracts on the phenolic bioaccesibility and bioavailability assessed by in vitro digestion and cell models

(2013) Laura Rubió et al.   FOOD CHEMISTRY

Semi-preparative isolation of dihydroresveratrol-3-O-β-d-glucuronide and four resveratrol conjugates from human urine after oral intake of a resveratrol-containing dietary supplement

(2013) Yulia Radko et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Changes in LDL Fatty Acid Composition as a Response to Olive Oil Treatment Are Inversely Related to Lipid Oxidative Damage: The EUROLIVE Study

(2013) Arrigo F.G. Cicero et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Health effects of olive oil polyphenols: Recent advances and possibilities for the use of health claims

(2013) Sandra Martín-Peláez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides

(2013) Andrew V. Stachulski et al.   NATURAL PRODUCT REPORTS

Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review

(2013) Janett Barbaresko et al.   NUTRITION REVIEWS

Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats

(2013) Aristotelis Kotronoulas et al.   PHARMACOLOGICAL RESEARCH

Citreoviridin enhances tumor necrosis factor-α-induced adhesion of human umbilical vein endothelial cells

(2013) Haifeng Hou et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

(2012) Daniele Del Rio et al.   ANTIOXIDANTS & REDOX SIGNALING

Validation of determination of plasma metabolites derived from thyme bioactive compounds by improved liquid chromatography coupled to tandem mass spectrometry

(2012) Laura Rubió et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids

(2012) Francisco Perez-Vizcaino et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Alpha-Tocopherol and BAY 11-7082 Reduce Vascular Cell Adhesion Molecule in Human Aortic Endothelial Cells

(2012) Úrsula Catalán et al.   JOURNAL OF VASCULAR RESEARCH

A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids

(2012) Karsten Beekmann et al.   Food & Function

Bioavailability of phenols from a phenol-enriched olive oil

(2011) Manuel Suárez et al.   BRITISH JOURNAL OF NUTRITION

The effect of olive oil polyphenols on antibodies against oxidized LDL. A randomized clinical trial

(2011) Olga Castañer et al.   CLINICAL NUTRITION

Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK–FOXO3a pathway

(2011) Houda Zrelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Hydroxytyrosol Is the Major Anti-Inflammatory Compound in Aqueous Olive Extracts and Impairs Cytokine and Chemokine Production in Macrophages

(2011) Nathalie Richard et al.   PLANTA MEDICA

Antioxidant Activities of Hydroxytyrosol Main Metabolites Do Not Contribute to Beneficial Health Effects after Olive Oil Ingestion

(2010) O. Khymenets et al.   DRUG METABOLISM AND DISPOSITION

Elevated Circulating LDL Phenol Levels in Men Who Consumed Virgin Rather Than Refined Olive Oil Are Associated with Less Oxidation of Plasma LDL

(2010) Karina de la Torre-Carbot et al.   JOURNAL OF NUTRITION

Heterogeneity and Standardization of Phase II Metabolism in Cultured Cells

(2009) Lucia Biasutto et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography–tandem mass spectrometry

(2009) Manuel Suárez et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cell Lines: A Tool for In Vitro Drug Metabolism Studies

(2008) M. Gomez-Lechon et al.   CURRENT DRUG METABOLISM

Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase

(2007) Yvonne Steffen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS