标题
IBD Candidate Genes and Intestinal Barrier Regulation
作者
关键词
-
出版物
INFLAMMATORY BOWEL DISEASES
Volume 20, Issue 10, Pages 1829-1849
出版商
Oxford University Press (OUP)
发表日期
2014-06-26
DOI
10.1097/mib.0000000000000090
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intestinal Permeability Defects: Is It Time to Treat?
- (2013) Matthew A. Odenwald et al. Clinical Gastroenterology and Hepatology
- PTPN2 is Associated with Crohn’s Disease and Its Expression Is Regulated by NKX2-3
- (2013) Wei Yu et al. DISEASE MARKERS
- Genetic Variants Synthesize to Produce Paneth Cell Phenotypes That Define Subtypes of Crohn's Disease
- (2013) Kelli L. VanDussen et al. GASTROENTEROLOGY
- Genome-wide Association Study Signal at the 12q12 Locus for Crohn’s Disease May Represent Associations with the MUC19 Gene
- (2013) Vijay Kumar et al. INFLAMMATORY BOWEL DISEASES
- Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohnʼs Disease, and Ulcerative Colitis Patients
- (2013) Scott Plevy et al. INFLAMMATORY BOWEL DISEASES
- Association Between the PTPN2 Gene and Crohnʼs Disease
- (2013) Valerie Marcil et al. INFLAMMATORY BOWEL DISEASES
- A lactoferrin-receptor, intelectin 1, affects uptake, sub-cellular localization and release of immunochemically detectable lactoferrin by intestinal epithelial Caco-2 cells
- (2013) Y. Akiyama et al. JOURNAL OF BIOCHEMISTRY
- Immunoproteomic to Identify Antigens in the Intestinal Mucosa of Crohn's Disease Patients
- (2013) Zheng Zhou et al. PLoS One
- Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2
- (2012) Declan F. McCole Annals of the New York Academy of Sciences
- Abnormal intestinal permeability in Crohn's disease pathogenesis
- (2012) Christopher W. Teshima et al. Annals of the New York Academy of Sciences
- Protective effects of lactoferrin chimera and bovine lactoferrin in a mouse model of enterohaemorrhagic Escherichia coli O157:H7 infection1This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.
- (2012) Héctor Flores-Villaseñor et al. Biochemistry and Cell Biology
- Implication of intestinal VDR deficiency in inflammatory bowel disease
- (2012) Jung-Hwan Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Roles of the Gel-Forming MUC2 Mucin and Its O-Glycosylation in the Protection against Colitis and Colorectal Cancer
- (2012) Hiroto Kawashima BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis
- (2012) Sarah Hopkins et al. DEVELOPMENTAL CELL
- PTP1B and TCPTP - nonredundant phosphatases in insulin signaling and glucose homeostasis
- (2012) Tony Tiganis FEBS Journal
- Loss of Claudins 2 and 15 From Mice Causes Defects in Paracellular Na+ Flow and Nutrient Transport in Gut and Leads to Death from Malnutrition
- (2012) Masami Wada et al. GASTROENTEROLOGY
- Association between genetic variants in the HNF4A gene and childhood-onset Crohn’s disease
- (2012) V Marcil et al. GENES AND IMMUNITY
- Genes Associated with Intestinal Permeability in Ulcerative Colitis: Changes in Expression Following Infliximab Therapy
- (2012) Gary Toedter et al. INFLAMMATORY BOWEL DISEASES
- Associations Between Vitamin D Receptor Polymorphisms and Susceptibility to Ulcerative Colitis and Crohnʼs Disease
- (2012) Le-Ning Xue et al. INFLAMMATORY BOWEL DISEASES
- Phenotype–Genotype Profiles in Crohnʼs Disease Predicted by Genetic Markers in Autophagy-Related Genes (GOIA Study II)
- (2012) Cecília Durães et al. INFLAMMATORY BOWEL DISEASES
- Lactoferrin moderates LPS-induced hypotensive response and gut injury in rats
- (2012) Marie-Francoise Doursout et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inflammatory bowel disease: an impaired barrier disease
- (2012) Simon Jäger et al. LANGENBECKS ARCHIVES OF SURGERY
- A role for myosin IXb, a motor–RhoGAP chimera, in epithelial wound healing and tight junction regulation
- (2012) Surjit K. Chandhoke et al. MOLECULAR BIOLOGY OF THE CELL
- Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
- (2012) Jeremiah R. McDole et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Intestinal barrier function in health and gastrointestinal disease
- (2012) M. Camilleri et al. NEUROGASTROENTEROLOGY AND MOTILITY
- PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background
- (2012) Jürgen Glas et al. PLoS One
- Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice
- (2012) Florian Wiede et al. PLoS One
- PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites
- (2012) Jürgen Glas et al. PLoS One
- Src tyrosine kinase phosphorylation of nuclear receptor HNF4 correlates with isoform-specific loss of HNF4 in human colon cancer
- (2012) K. Chellappa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor
- (2012) Carsten Carlberg et al. STEROIDS
- NHE3 modulates the severity of colitis in IL-10-deficient mice
- (2011) C. B. Larmonier et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution
- (2011) Toshimitsu Yamaoka et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Tight Junction Pore and Leak Pathways: A Dynamic Duo
- (2011) Le Shen et al. Annual Review of Physiology
- Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells
- (2011) Hideyuki Yamawaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Role of mucus layers in gut infection and inflammation
- (2011) Gunnar C Hansson CURRENT OPINION IN MICROBIOLOGY
- Common variation in the vitamin D receptor gene and risk of inflammatory bowel disease in an Irish case–control study
- (2011) David J. Hughes et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease
- (2011) Michael Schumann et al. GUT
- Replication of genetic variation in the MYO9B gene in Crohn's disease
- (2011) Victorien M. Wolters et al. HUMAN IMMUNOLOGY
- Epithelial barrier: an interface for the cross-communication between gut flora and immune system
- (2011) Yoshiyuki Goto et al. IMMUNOLOGICAL REVIEWS
- Loss of downregulated in adenoma (DRA) impairs mucosal HCO3− secretion in murine ileocolonic inflammation
- (2011) Fang Xiao et al. INFLAMMATORY BOWEL DISEASES
- Protein Tyrosine Phosphatase Nonreceptor Type 2 Regulates Autophagosome Formation in Human Intestinal Cells
- (2011) Michael Scharl et al. INFLAMMATORY BOWEL DISEASES
- Crohnʼs disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy
- (2011) Michael Scharl et al. INFLAMMATORY BOWEL DISEASES
- NOD2 exonic variations in Iranian Crohn's disease patients
- (2011) Nosratollah Naderi et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Impenetrable barriers or entry portals? The role of cell–cell adhesion during infection
- (2011) Matteo Bonazzi et al. JOURNAL OF CELL BIOLOGY
- CFTR anion channel modulates expression of human transmembrane mucin MUC3 through the PDZ protein GOPC
- (2011) T. Pelaseyed et al. JOURNAL OF CELL SCIENCE
- Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut
- (2011) N J Mantis et al. Mucosal Immunology
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
- (2011) Manuel A Rivas et al. NATURE GENETICS
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- Low body mass not vitamin D receptor polymorphisms predict osteoporosis in patients with inflammatory bowel disease
- (2010) C. L. NOBLE et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Susceptibility loci reported in genome-wide association studies are associated with Crohn’s disease in Canadian children
- (2010) D. K. AMRE et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- KCNN4 Gene Variant Is Associated With Ileal Crohn's Disease in the Australian and New Zealand Population
- (2010) Lisa A Simms et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Cytoskeletal Regulation of Epithelial Barrier Function During Inflammation
- (2010) Andrei I. Ivanov et al. AMERICAN JOURNAL OF PATHOLOGY
- PGE2 promotes Ca2+-mediated epithelial barrier disruption through EP1 and EP4 receptors in Caco-2 cell monolayers
- (2010) M. José Rodríguez-Lagunas et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Loss of protein tyrosine phosphatase N2 potentiates epidermal growth factor suppression of intestinal epithelial chloride secretion
- (2010) Michael Scharl et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Role of EP4 receptor and prostaglandin transporter in prostaglandin E2-induced alteration in colonic epithelial barrier integrity
- (2010) Manigandan Lejeune et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Segregation of Na/H exchanger-3 and Cl/HCO3 exchanger SLC26A3 (DRA) in rodent cecum and colon
- (2010) Colleen Talbot et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Inflammatory Bowel Disease
- (2010) Arthur Kaser et al. Annual Review of Immunology
- A novel antagonist of the prostaglandin E2 EP4 receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models
- (2010) Q Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Tight Junction Protein, Occludin, Regulates the Directional Migration of Epithelial Cells
- (2010) Dan Du et al. DEVELOPMENTAL CELL
- Protein tyrosine phosphatase N2 regulates TNF -induced signalling and cytokine secretion in human intestinal epithelial cells
- (2010) M. Scharl et al. GUT
- Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease
- (2010) Gilles Laverny et al. IMMUNOLOGY LETTERS
- Association of the NOD2 genotype with bacterial translocation via altered cell–cell contacts in Crohnʼs disease patients
- (2010) Katrin Kosovac et al. INFLAMMATORY BOWEL DISEASES
- Toll-like receptors in inflammatory bowel diseases: A decade later
- (2010) Elke Cario INFLAMMATORY BOWEL DISEASES
- Genetics of ulcerative colitis
- (2010) Alexandra I. Thompson et al. INFLAMMATORY BOWEL DISEASES
- Distinct and overlapping genetic loci in crohnʼs disease and ulcerative colitis: Correlations with pathogenesis
- (2010) Matti Waterman et al. INFLAMMATORY BOWEL DISEASES
- Importance of disrupted intestinal barrier in inflammatory bowel diseases
- (2010) Saʼad Y. Salim et al. INFLAMMATORY BOWEL DISEASES
- HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort
- (2010) Suzanne van Sommeren et al. INFLAMMATORY BOWEL DISEASES
- Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity
- (2010) Christopher R. Weber et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
- (2010) Amanda M. Marchiando et al. JOURNAL OF CELL BIOLOGY
- Occludin is required for cytokine-induced regulation of tight junction barriers
- (2010) C. M. Van Itallie et al. JOURNAL OF CELL SCIENCE
- Genome-wide association identifies multiple ulcerative colitis susceptibility loci
- (2010) Dermot P B McGovern et al. NATURE GENETICS
- Gut Microbiota in Health and Disease
- (2010) Inna Sekirov et al. PHYSIOLOGICAL REVIEWS
- Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse
- (2010) Syed-Wajahat Hassan et al. PLoS One
- Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis
- (2010) L. Di et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics and functions of tight junctions
- (2010) Emily Steed et al. TRENDS IN CELL BIOLOGY
- Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease
- (2010) Patrick Danoy et al. PLoS Genetics
- Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk
- (2009) Eleonora AM Festen et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Confirmation of Multiple Crohn's Disease Susceptibility Loci in a Large Dutch–Belgian Cohort
- (2009) Rinse K Weersma et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Hepatocyte nuclear factor 4α contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation
- (2009) Jean-Philippe Babeu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis
- (2009) Pallavi Garg et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Dynamic Regulation of Epithelial Cell Fate and Barrier Function by Intercellular Junctions
- (2009) Stefan Koch et al. Annals of the New York Academy of Sciences
- Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15− Crohn's disease patients
- (2009) Ana Márquez et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Mechanism of cytokine modulation of epithelial tight junction barrier
- (2009) Rana Al-Sadi Frontiers in Bioscience-Landmark
- Polymorphisms in E-cadherin (CDH1) result in a mis-localised cytoplasmic protein that is associated with Crohn's disease
- (2009) A. M. Muise et al. GUT
- Guanine Nucleotide-Binding Proteins of the G12 Family Shape Immune Functions by Controlling CD4+ T Cell Adhesiveness and Motility
- (2009) Susanne Herroeder et al. IMMUNITY
- Association between genetic variants in myosin IXB and Crohnʼs disease
- (2009) Rachel Cooney et al. INFLAMMATORY BOWEL DISEASES
- Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion
- (2009) Mary Abigail S. Garcia et al. JOURNAL OF CLINICAL INVESTIGATION
- Tissue Distribution of Murine Muc19/Smgc Gene Products
- (2009) Biswadip Das et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Hepatocyte Nuclear Factor 4 , a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium
- (2009) A.-L. Cattin et al. MOLECULAR AND CELLULAR BIOLOGY
- Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
- (2009) Mark S Silverberg et al. NATURE GENETICS
- Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
- (2009) Chengcan Yao et al. NATURE MEDICINE
- Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice
- (2009) Mathieu Darsigny et al. PLoS One
- Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
- (2009) A. Tripathi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Physiology and Function of the Tight Junction
- (2009) J. M. Anderson et al. Cold Spring Harbor Perspectives in Biology
- Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation
- (2008) Francesco Raimondi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Calcium and phosphate homeostasis: Concerted interplay of new regulators
- (2008) Kirsten Y. Renkema et al. ANNALS OF MEDICINE
- Role of Down-Regulated in Adenoma Anion Exchanger in HCO3– Secretion Across Murine Duodenum
- (2008) Nancy M. Walker et al. GASTROENTEROLOGY
- Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis
- (2008) Liping Su et al. GASTROENTEROLOGY
- Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
- (2008) M C Arrieta et al. GUT
- The Biology of Intestinal Immunoglobulin A Responses
- (2008) Andrea Cerutti et al. IMMUNITY
- Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease
- (2008) Sung-Hoon Ahn et al. INFLAMMATORY BOWEL DISEASES
- MAGI2 genetic variation and inflammatory bowel disease
- (2008) Dermot P.B. McGovern et al. INFLAMMATORY BOWEL DISEASES
- Intestinal barrier dysfunction in inflammatory bowel diseases
- (2008) Michael A. McGuckin et al. INFLAMMATORY BOWEL DISEASES
- A single-nucleotide polymorphism in intelectin 1 is associated with increased asthma risk
- (2008) Alan D. Pemberton et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- G 12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly
- (2008) E. Sabath et al. JOURNAL OF CELL SCIENCE
- Interaction of Extracellular Matrix Protein 1 with Extracellular Matrix Components: ECM1 Is a Basement Membrane Protein of the Skin
- (2008) Sandy Sercu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- MF498 [N- -2-(2-methoxyphenyl)acetamide], a Selective E Prostanoid Receptor 4 Antagonist, Relieves Joint Inflammation and Pain in Rodent Models of Rheumatoid and Osteoarthritis
- (2008) P. Clark et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis
- (2008) Paul M Quinton LANCET
- Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
- (2008) Andre Franke et al. NATURE GENETICS
- Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
- (2008) NATURE GENETICS
- Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
- (2008) Sheila A Fisher et al. NATURE GENETICS
- Common variants at 30 loci contribute to polygenic dyslipidemia
- (2008) Sekar Kathiresan et al. NATURE GENETICS
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
- (2008) Deborah J. Smyth et al. NEW ENGLAND JOURNAL OF MEDICINE
- The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
- (2008) M. E. V. Johansson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier
- (2007) Juan Kong et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Crosstalk of tight junction components with signaling pathways
- (2007) Lorenza González-Mariscal et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
- (2007) Andrea Hartsock et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
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