Importance of disrupted intestinal barrier in inflammatory bowel diseases

VSL#3 Probiotic Upregulates Intestinal Mucosal Alkaline Sphingomyelinase and Reduces Inflammation

(2016) Isaac Soo et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Microbial Colonization Drives Expansion of IL-1 Receptor 1-Expressing and IL-17-Producing γ/δ T Cells

(2010) Jinyou Duan et al.   Cell Host & Microbe

Human TSLP-Educated DCs

(2010) Jiongkun Wang et al.   Cellular & Molecular Immunology

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

(2010) R. DUCHMANN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

(2010) T. T. MACDONALD et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Probiotic lactobacilli and VSL#3 induce enterocyte β-defensin 2

(2010) M. Schlee et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture

(2010) K. Lindfors et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)

(2010) Andre Franke et al.   NATURE GENETICS

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens

(2010) Sarah Lebeer et al.   NATURE REVIEWS MICROBIOLOGY

Moving forward: polarised trafficking in cell migration

(2010) Sarah J. Fletcher et al.   TRENDS IN CELL BIOLOGY

Increased Transmucosal Uptake of E. coli K12 in Collagenous Colitis Persists After Budesonide Treatment

(2009) Andreas Münch et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk

(2009) Eleonora AM Festen et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A guide to Ussing chamber studies of mouse intestine

(2009) Lane L. Clarke   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Role of JAM-A in Inflammatory Bowel Disease: Unrevealing the Ties That Bind

(2009) Stefania Vetrano et al.   Annals of the New York Academy of Sciences

Epithelial Tight Junctions in Intestinal Inflammation

(2009) Joerg D. Schulzke et al.   Annals of the New York Academy of Sciences

Tight Junctions

(2009) Jörg-Dieter Schulzke et al.   Annals of the New York Academy of Sciences

A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease

(2009) Ken Cadwell et al.   Autophagy

Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease

(2009) D. C. Baumgart et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Genetic Basis of Inflammatory Bowel Disease

(2009) Rachel Cooney et al.   DIGESTIVE DISEASES

M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis

(2009) Sinead C. Corr et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Beneficial effects of Bacteroides fragilis polysaccharides on the immune system

(2009) Erin et al.   Frontiers in Bioscience-Landmark

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

Th1/Th17 Immune Response Is Induced by Mesenteric Lymph Node Dendritic Cells in Crohn's Disease

(2009) Atsushi Sakuraba et al.   GASTROENTEROLOGY

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

(2009) I D Iliev et al.   GUT

Differential regulation of interleukin 17 and interferon   production in inflammatory bowel disease

(2009) L. Rovedatti et al.   GUT

Immune Responses to the Microbiota at the Intestinal Mucosal Surface

(2009) Breck A. Duerkop et al.   IMMUNITY

M-Cell Targeting of Whole Killed Bacteria Induces Protective Immunity against Gastrointestinal Pathogens

(2009) Y.-T. Chionh et al.   INFECTION AND IMMUNITY

Low counts of Faecalibacterium prausnitzii in colitis microbiota

(2009) H. Sokol et al.   INFLAMMATORY BOWEL DISEASES

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

(2009) Betsy C. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory bowel disease: review from the aspect of genetics

(2009) Shunji Ishihara et al.   JOURNAL OF GASTROENTEROLOGY

Evolving paradigms in the pathogenesis of IBD

(2009) Lloyd Mayer   JOURNAL OF GASTROENTEROLOGY

Probiotics and immunity

(2009) Andrea T. Borchers et al.   JOURNAL OF GASTROENTEROLOGY

Mechanism of Interferon-γ–Induced Increase in T84 Intestinal Epithelial Tight Junction

(2009) Michel A. Boivin et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Analysis of Unstirred Water Layer in In Vitro Permeability Experiments

(2009) Timo Korjamo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Paracellular Porosity and Pore Size of the Human Intestinal Epithelium in Tissue and Cell Culture Models

(2009) Johanna Linnankoski et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid raft organization and function in the small intestinal brush border

(2009) E. M. Danielsen et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

(2009) Susanne M. Krug et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Do symbiotic bacteria subvert host immunity?

(2009) Lora V. Hooper   NATURE REVIEWS MICROBIOLOGY

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

(2009) A. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The claudins

(2009) Madhu Lal-Nag et al.   GENOME BIOLOGY

CD83+CCR7− Dendritic Cells Accumulate in the Subepithelial Dome and Internalize Translocated Escherichia coli HB101 in the Peyer's Patches of Ileal Crohn's Disease

(2008) Sa'ad Y. Salim et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular components of the adherens junction

(2008) Carien M. Niessen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Permeability for Intestinal Absorption: Caco-2 Assay and Related Issues

(2008) Barry Press et al.   CURRENT DRUG METABOLISM

Toll-Like Receptor Signaling in Small Intestinal Epithelium Promotes B-Cell Recruitment and IgA Production in Lamina Propria

(2008) Limin Shang et al.   GASTROENTEROLOGY

Unique Role of Junctional Adhesion Molecule-A in Maintaining Mucosal Homeostasis in Inflammatory Bowel Disease

(2008) Stefania Vetrano et al.   GASTROENTEROLOGY

The intestinal stem cell

(2008) N. Barker et al.   GENES & DEVELOPMENT

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

(2008) T Kobayashi et al.   GUT

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

(2008) M C Arrieta et al.   GUT

Predicting relapse in Crohn's disease: a biopsychosocial model

(2008) A Bitton et al.   GUT

Intestinal epithelial barrier dysfunction and dendritic cell redistribution during early stages of inflammation in the rat: Role for TLR-2 and -4 blockage

(2008) Manuel A. Silva et al.   INFLAMMATORY BOWEL DISEASES

Probiotic administration in patients with ileal pouch–anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells

(2008) Annamaria Pronio et al.   INFLAMMATORY BOWEL DISEASES

Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: A pilot study

(2008) Hien Q. Huynh et al.   INFLAMMATORY BOWEL DISEASES

Increased uptake of non-pathogenicE. coli via the follicle-associated epithelium in longstanding ileal Crohn's disease

(2008) ÅV Keita et al.   JOURNAL OF PATHOLOGY

Molecular mechanism of intestinal permeability: interaction at tight junctions

(2008) Zakir Hossain et al.   Molecular BioSystems

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

(2008) Petric Kuballa et al.   PLoS One

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence ofSaccharomyces boulardiion the intestinal permeability of patients with Crohn's disease in remission

(2008) Eduardo Garcia Vilela et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Crohn’s disease-Defect in innate defence

(2008) Michael Gersemann et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Transmembrane proteins of tight junctions

(2007) Hideki Chiba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES