PTP1B and TCPTP - nonredundant phosphatases in insulin signaling and glucose homeostasis

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

(2011) Abdelali Agouni et al.   BIOCHEMICAL JOURNAL

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

Brain Insulin Controls Adipose Tissue Lipolysis and Lipogenesis

(2011) Thomas Scherer et al.   Cell Metabolism

Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance

(2011) Kim Loh et al.   Cell Metabolism

T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice

(2011) K. Loh et al.   DIABETOLOGIA

TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway

(2011) S. Kant et al.   GENES & DEVELOPMENT

Differential Regulation of Endoplasmic Reticulum Stress by Protein Tyrosine Phosphatase 1B and T Cell Protein Tyrosine Phosphatase

(2011) Ahmed Bettaieb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

(2011) Florian Wiede et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylated Grb14 Is an Endogenous Inhibitor of Retinal Protein Tyrosine Phosphatase 1B, and Light-Dependent Activation of Src Phosphorylates Grb14

(2011) D. K. Basavarajappa et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B

(2011) Kosuke Matsuo et al.   PLoS One

Berberine inhibits PTP1B activity and mimics insulin action

(2010) Chunhua Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis

(2010) Atsushi Fukushima et al.   DIABETES

Protein tyrosine phosphatase N2 regulates TNF -induced signalling and cytokine secretion in human intestinal epithelial cells

(2010) M. Scharl et al.   GUT

Pathogenesis of Insulin Resistance in Skeletal Muscle

(2010) Muhammad A. Abdul-Ghani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Protein Tyrosine Phosphatase-1B (PTP-1B) Knockdown Improves Palmitate-Induced Insulin Resistance in C2C12 Skeletal Muscle Cells

(2010) Salar Bakhtiyari et al.   LIPIDS

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reactive oxygen species and insulin resistance: the good, the bad and the ugly

(2010) Tony Tiganis   TRENDS IN PHARMACOLOGICAL SCIENCES

Prevention of Steatosis by Hepatic JNK1

(2009) Guadalupe Sabio et al.   Cell Metabolism

Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli

(2009) Soledad Miranda et al.   CELLULAR SIGNALLING

Deletion of Protein Tyrosine Phosphatase 1b Improves Peripheral Insulin Resistance and Vascular Function in Obese, Leptin-Resistant Mice via Reduced Oxidant Tone

(2009) M. Irfan Ali et al.   CIRCULATION RESEARCH

Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice

(2009) A. Gonzalez-Rodriguez et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Role of Muscle c-Jun NH2-Terminal Kinase 1 in Obesity-Induced Insulin Resistance

(2009) G. Sabio et al.   MOLECULAR AND CELLULAR BIOLOGY

PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling

(2008) X. Lu et al.   BLOOD

DNA Replication Stalling Attenuates Tyrosine Kinase Signaling to Suppress S Phase Progression

(2008) Ben J. Shields et al.   CANCER CELL

Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes

(2008) Yvonne Ng et al.   Cell Metabolism

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

(2008) M. Delibegovic et al.   DIABETES

Reduction of Hypothalamic Protein Tyrosine Phosphatase Improves Insulin and Leptin Resistance in Diet-Induced Obese Rats

(2008) Paty Karoll Picardi et al.   ENDOCRINOLOGY

Regulation of the Met Receptor-tyrosine Kinase by the Protein-tyrosine Phosphatase 1B and T-cell Phosphatase

(2008) Veena Sangwan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo

(2008) Janice M. Zabolotny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

(2008) Deborah J. Smyth et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance

(2008) G. Sabio et al.   SCIENCE