Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Proinflammatory cytokines underlying the inflammation of Crohnʼs disease

(2010) Warren Strober et al.   CURRENT OPINION IN GASTROENTEROLOGY

Protein Tyrosine Phosphatase non-Receptor Type 2 regulates IFN-γ-induced cytokine signaling in THP-1 monocytes

(2010) Michael Scharl et al.   INFLAMMATORY BOWEL DISEASES

Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse

(2010) Syed-Wajahat Hassan et al.   PLoS One

Confirmation of Multiple Crohn's Disease Susceptibility Loci in a Large Dutch–Belgian Cohort

(2009) Rinse K Weersma et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

Interferon-γ Regulation of Intestinal Epithelial Permeability

(2009) Cécile Beaurepaire et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The density of small tight junction pores varies among cell types and is increased by expression of claudin-2

(2008) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

(2008) Sheila A Fisher et al.   NATURE GENETICS