New Frontiers in Type III Secretion Biology: the Chlamydia Perspective

The chlamydial OTU domain-containing proteinChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52

(2013) Ana Rita Furtado et al.   CELLULAR MICROBIOLOGY

Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity

(2013) P. Engstrom et al.   JOURNAL OF BACTERIOLOGY

Dendrimer-enabled DNA delivery and transformation of Chlamydia pneumoniae

(2013) Hervé C. Gérard et al.   Nanomedicine-Nanotechnology Biology and Medicine

Identification of Novel Type III Secretion Chaperone-Substrate Complexes of Chlamydia trachomatis

(2013) Sara V. Pais et al.   PLoS One

A C. trachomatis Cloning Vector and the Generation of C. trachomatis Strains Expressing Fluorescent Proteins under the Control of a C. trachomatis Promoter

(2013) Hervé Agaisse et al.   PLoS One

Chlamydia trachomatis Inclusion Membrane Protein CT228 Recruits Elements of the Myosin Phosphatase Pathway to Regulate Release Mechanisms

(2013) Erika I. Lutter et al.   Cell Reports

Genus-optimized strategy for the identification of chlamydial type III secretion substrates

(2013) Kelley M. Hovis et al.   Pathogens and Disease

Chlamydia trachomatis Tarp cooperates with the Arp2/3 complex to increase the rate of actin polymerization

(2012) Shahanawaz Jiwani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolution and Conservation of Predicted Inclusion Membrane Proteins in Chlamydiae

(2012) Erika I. Lutter et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Expanded Roles for Multicargo and Class 1B Effector Chaperones in Type III Secretion

(2012) N. A. Thomas et al.   JOURNAL OF BACTERIOLOGY

Polymorphisms in Inc Proteins and Differential Expression ofincGenes among Chlamydia trachomatis Strains Correlate with Invasiveness and Tropism of Lymphogranuloma Venereum Isolates

(2012) Filipe Almeida et al.   JOURNAL OF BACTERIOLOGY

Domain Analyses Reveal ThatChlamydia trachomatisCT694 Protein Belongs to the Membrane-localized Family of Type III Effector Proteins

(2012) Holly D. Bullock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Export According to Schedule: Architecture, Assembly, and Regulation of Type III Secretion Systems from Plant- and Animal-Pathogenic Bacteria

(2012) D. Buttner   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Dendrimer-Enabled Modulation of Gene Expression in Chlamydia trachomatis

(2012) Manoj K. Mishra et al.   MOLECULAR PHARMACEUTICS

Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803

(2012) Chris B. Stone et al.   PLoS One

Exploration of Chlamydial Type III Secretion System Reconstitution in Escherichia coli

(2012) Xiaofeng Bao et al.   PLoS One

Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches

(2012) B. D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental stage-specific metabolic and transcriptional activity of Chlamydia trachomatis in an axenic medium

(2012) A. Omsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ChlamydiaeAssemble a Pathogen Synapse to Hijack the Host Endoplasmic Reticulum

(2012) Maud Dumoux et al.   TRAFFIC

Bacterial effector interplay: a new way to view effector function

(2012) Stephanie R. Shames et al.   TRENDS IN MICROBIOLOGY

The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

(2012) Sophie S. Abby et al.   PLoS Genetics

Multi-genome identification and characterization of chlamydiae-specific type III secretion substrates: the Inc proteins

(2011) Pierre Dehoux et al.   BMC GENOMICS

Bacterial subversion of host actin dynamics at the plasma membrane

(2011) Rey Carabeo   CELLULAR MICROBIOLOGY

Biochemical and Localization Analyses of Putative Type III Secretion Translocator Proteins CopB and CopB2 of Chlamydia trachomatis Reveal Significant Distinctions

(2011) B. Chellas-Géry et al.   INFECTION AND IMMUNITY

Disulfide Bonding within Components of the Chlamydia Type III Secretion Apparatus Correlates with Development

(2011) H. J. Betts-Hampikian et al.   JOURNAL OF BACTERIOLOGY

Scc1 (CP0432) and Scc4 (CP0033) Function as a Type III Secretion Chaperone for CopN of Chlamydia pneumoniae

(2011) E. Silva-Herzog et al.   JOURNAL OF BACTERIOLOGY

TheChlamydiaEffector Chlamydial Outer Protein N (CopN) Sequesters Tubulin and Prevents Microtubule Assembly

(2011) Tara L. Archuleta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subversion of membrane transport pathways by vacuolar pathogens

(2011) Eric Alix et al.   JOURNAL OF CELL BIOLOGY

Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1

(2011) S. Gong et al.   MICROBIOLOGY-SGM

Chlamydia trachomatis Slc1 is a type III secretion chaperone that enhances the translocation of its invasion effector substrate TARP

(2011) Amanda J. Brinkworth et al.   MOLECULAR MICROBIOLOGY

Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms

(2011) Hector A. Saka et al.   MOLECULAR MICROBIOLOGY

Generation of targeted Chlamydia trachomatis null mutants

(2011) L. Kari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Secretion Chaperones

(2011) Juliana Fattori et al.   PROTEIN AND PEPTIDE LETTERS

The Lipid Transfer Protein CERT Interacts with the Chlamydia Inclusion Protein IncD and Participates to ER-Chlamydia Inclusion Membrane Contact Sites

(2011) Isabelle Derré et al.   PLoS Pathogens

Development of a Transformation System for Chlamydia trachomatis: Restoration of Glycogen Biosynthesis by Acquisition of a Plasmid Shuttle Vector

(2011) Yibing Wang et al.   PLoS Pathogens

The Chlamydial Type III Secretion Mechanism: Revealing Cracks in a Tough Nut

(2011) Helen Jennifer Betts-Hampikian et al.   Frontiers in Microbiology

Interactions between flagellar and type III secretion proteins in Chlamydia pneumoniae

(2010) Chris B Stone et al.   BMC MICROBIOLOGY

Specific chlamydial inclusion membrane proteins associate with active Src family kinases in microdomains that interact with the host microtubule network

(2010) Jeffrey Mital et al.   CELLULAR MICROBIOLOGY

Identification of a Family of Effectors Secreted by the Type III Secretion System That Are Conserved in Pathogenic Chlamydiae

(2010) Sandra Muschiol et al.   INFECTION AND IMMUNITY

Genome Sequencing of Recent Clinical Chlamydia trachomatis Strains Identifies Loci Associated with Tissue Tropism and Regions of Apparent Recombination

(2010) B. M. Jeffrey et al.   INFECTION AND IMMUNITY

The Conserved Tarp Actin Binding Domain Is Important for Chlamydial Invasion

(2010) Travis J. Jewett et al.   PLoS Pathogens

Histone Methylation by NUE, a Novel Nuclear Effector of the Intracellular Pathogen Chlamydia trachomatis

(2010) Meghan E. Pennini et al.   PLoS Pathogens

Biophysical Characterization ofChlamydia trachomatisCT584 Supports Its Potential Role as a Type III Secretion Needle Tip Protein

(2009) Aaron P. Markham et al.   BIOCHEMISTRY

Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

(2009) Sandra Muschiol et al.   BMC MICROBIOLOGY

A protein secreted by the respiratory pathogenChlamydia pneumoniaeimpairs IL-17 signalling via interaction with human Act1

(2009) Katerina Wolf et al.   CELLULAR MICROBIOLOGY

Identification ofChlamydia trachomatisCT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus

(2009) Anne-Sofie Hobolt-Pedersen et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

A regulator from Chlamydia trachomatis modulates the activity of RNA polymerase through direct interaction with the   subunit and the primary   subunit

(2009) X. Rao et al.   GENES & DEVELOPMENT

Evidence that CT694 is a novelChlamydia trachomatisT3S substrate capable of functioning during invasion or early cycle development

(2009) S. Hower et al.   MOLECULAR MICROBIOLOGY

Intracellular Bacteria Encode Inhibitory SNARE-Like Proteins

(2009) Fabienne Paumet et al.   PLoS One

The Chlamydia Type III Secretion System C-ring Engages a Chaperone-Effector Protein Complex

(2009) Kris E. Spaeth et al.   PLoS Pathogens

Accurate Prediction of Secreted Substrates and Identification of a Conserved Putative Secretion Signal for Type III Secretion Systems

(2009) Ram Samudrala et al.   PLoS Pathogens

Sequence-Based Prediction of Type III Secreted Proteins

(2009) Roland Arnold et al.   PLoS Pathogens

Chlamydia trachomatis tarp is phosphorylated by src family tyrosine kinases

(2008) Travis J. Jewett et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Control of gene expression by type III secretory activity

(2008) Evan D Brutinel et al.   CURRENT OPINION IN MICROBIOLOGY

Complex kinase requirements forChlamydia trachomatisTarp phosphorylation

(2008) Adrian Mehlitz et al.   FEMS MICROBIOLOGY LETTERS

Interactions between CdsD, CdsQ, and CdsL, Three Putative Chlamydophila pneumoniae Type III Secretion Proteins

(2008) D. L. Johnson et al.   JOURNAL OF BACTERIOLOGY

Structural Characterization of the Yersinia pestis Type III Secretion System Needle Protein YscF in Complex with Its Heterodimeric Chaperone YscE/YscG

(2008) Ping Sun et al.   JOURNAL OF MOLECULAR BIOLOGY

The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth

(2008) Jin Huang et al.   NATURE

Transformation and isolation of allelic exchange mutants of Chlamydia psittaci using recombinant DNA introduced by electroporation

(2008) R. Binet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNARE Protein Mimicry by an Intracellular Bacterium

(2008) Cédric Delevoye et al.   PLoS Pathogens

Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors

(2008) B. Josh Lane et al.   PLoS Pathogens