Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity

Chlamydia trachomatis Plasmid-Encoded Pgp4 Is a Transcriptional Regulator of Virulence-Associated Genes

(2013) Lihua Song et al.   INFECTION AND IMMUNITY

Resistance to a Novel Antichlamydial Compound Is Mediated through Mutations inChlamydia trachomatis secY

(2012) Kelsi M. Sandoz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Thinking outside the box: new strategies for antichlamydial control

(2012) Raphael H Valdivia   Future Microbiology

Actin Recruitment to the Chlamydia Inclusion Is Spatiotemporally Regulated by a Mechanism That Requires Host and Bacterial Factors

(2012) Elizabeth Chin et al.   PLoS One

Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches

(2012) B. D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol

(2011) Xiang Wu et al.   BMC MICROBIOLOGY

The Chlamydia Protease CPAF Regulates Host and Bacterial Proteins to Maintain Pathogen Vacuole Integrity and Promote Virulence

(2011) Ine Jorgensen et al.   Cell Host & Microbe

Recent advances in bacterial heme protein biochemistry

(2011) Jeffery A Mayfield et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Biochemical and Localization Analyses of Putative Type III Secretion Translocator Proteins CopB and CopB2 of Chlamydia trachomatis Reveal Significant Distinctions

(2011) B. Chellas-Géry et al.   INFECTION AND IMMUNITY

Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

(2011) Dai Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of Mice From a Chlamydia trachomatis Vaginal Infection Using a Salicylidene Acylhydrazide, a Potential Microbicide

(2011) A. Slepenkin et al.   JOURNAL OF INFECTIOUS DISEASES

Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1

(2011) S. Gong et al.   MICROBIOLOGY-SGM

Generation of targeted Chlamydia trachomatis null mutants

(2011) L. Kari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia

(2010) Markus K. Dahlgren et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chlamydia trachomatisPersistence In Vitro: An Overview

(2010) Priscilla B. Wyrick   JOURNAL OF INFECTIOUS DISEASES

Heme biosynthesis is coupled to electron transport chains for energy generation

(2010) K. Mobius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Small Molecules To Dissect Mechanisms of Microbial Pathogenesis

(2009) Aaron W. Puri et al.   ACS Chemical Biology

Identification ofEscherichia coliHemG as a Novel, Menadione-Dependent Flavodoxin with Protoporphyrinogen Oxidase Activity

(2009) Tye O. Boynton et al.   BIOCHEMISTRY

Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

(2009) Sandra Muschiol et al.   BMC MICROBIOLOGY

New insights intoChlamydiaintracellular survival mechanisms

(2009) Jordan L. Cocchiaro et al.   CELLULAR MICROBIOLOGY

Effector protein modulation of host cells: examples in the Chlamydia spp. arsenal

(2009) Helen J Betts et al.   CURRENT OPINION IN MICROBIOLOGY

Identification ofChlamydia trachomatisCT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus

(2009) Anne-Sofie Hobolt-Pedersen et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

A comparative study of RNA and DNA as internal gene expression controls early in the developmental cycle ofChlamydia pneumoniae

(2009) Patrik Engström et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in Salmonella enterica serovar Typhimurium is associated with iron restriction and can be reversed by free iron

(2009) Abigail N. Layton et al.   FEMS MICROBIOLOGY LETTERS

Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis

(2009) Xiaohong Qin et al.   JOURNAL OF STRUCTURAL BIOLOGY

Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ

(2009) Illya Tietzel et al.   PLoS One

Chlamydiae as Symbionts in Eukaryotes

(2008) Matthias Horn   Annual Review of Microbiology

The biochemistry of heme biosynthesis

(2008) Ilka U. Heinemann et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Spatial constraints within the chlamydial host cell inclusion predict interrupted development and persistence

(2008) Alexander Hoare et al.   BMC MICROBIOLOGY

Chlamydia effector proteins and new insights into chlamydial cellular microbiology

(2008) Raphael H Valdivia   CURRENT OPINION IN MICROBIOLOGY

Role for the Chlamydial Type III Secretion Apparatus in Host Cytokine Expression

(2008) D. Prantner et al.   INFECTION AND IMMUNITY

Small-Molecule Type III Secretion System Inhibitors Block Assembly of the Shigella Type III Secreton

(2008) A. K. J. Veenendaal et al.   JOURNAL OF BACTERIOLOGY

Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

(2008) P. Keyser et al.   JOURNAL OF INTERNAL MEDICINE

Transformation and isolation of allelic exchange mutants of Chlamydia psittaci using recombinant DNA introduced by electroporation

(2008) R. Binet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA