Functional effects of 13 rarePRSS1variants presumed to cause chronic pancreatitis

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk

(2012) Sebastian Beer et al.   GUT

CFTR,SPINK1,CTRCandPRSS1variants in chronic pancreatitis: is the role of mutatedCFTRoverestimated?

(2012) Jonas Rosendahl et al.   GUT

Increased Activation of Hereditary Pancreatitis-associated Human Cationic Trypsinogen Mutants in Presence of Chymotrypsin C

(2012) András Szabó et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

(2012) David C Whitcomb et al.   NATURE GENETICS

High Affinity Small Protein Inhibitors of Human Chymotrypsin C (CTRC) Selected by Phage Display Reveal Unusual Preference for P4′ Acidic Residues

(2011) András Szabó et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis

(2011) Yeoun Joo Lee et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Genetic Prevalence and Characteristics in Children With Recurrent Pancreatitis

(2011) Mutaz Sultan et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

New PRSS1 and common CFTR mutations in a child with acute recurrent pancreatitis, could be considered an "Hereditary" form of pancreatitis ?

(2010) Vito D Corleto et al.   BMC GASTROENTEROLOGY

Uncertainties in the classification of human cationic trypsinogen (PRSS1) variants as hereditary pancreatitis-associated mutations

(2010) R. Szmola et al.   JOURNAL OF MEDICAL GENETICS

Association and differential role of PRSS1 and SPINK1 mutation in early-onset and late-onset idiopathic chronic pancreatitis in Chinese subjects

(2009) Y-T Chang et al.   GUT

Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells

(2009) R. Szmola et al.   GUT

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism

(2009) Éva Kereszturi et al.   HUMAN MUTATION

The natural history of hereditary pancreatitis: a national series

(2008) V Rebours et al.   GUT

Trypsinogen Copy Number Mutations in Patients With Idiopathic Chronic Pancreatitis

(2007) Emmanuelle Masson et al.   Clinical Gastroenterology and Hepatology