Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

What is personalized medicine and what should it replace?

(2012) David C. Whitcomb   Nature Reviews Gastroenterology & Hepatology

Claudin-1, Claudin-2 and Claudin-11 Genes Differentially Associate with Distinct Types of Anti-inflammatory Macrophages In vitro and with Parasite- and Tumour-elicited Macrophages In vivo

(2012) J. Van den Bossche et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Intra-acinar Trypsinogen Activation Mediates Early Stages of Pancreatic Injury but Not Inflammation in Mice With Acute Pancreatitis

(2011) Rajinder Dawra et al.   GASTROENTEROLOGY

Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium

(2011) Takuya Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

(2011) Taye H. Hamza et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

The role of alcohol and smoking in pancreatitis

(2010) Dhiraj Yadav et al.   Nature Reviews Gastroenterology & Hepatology

Chronic Pancreatitis: Genetics and Pathogenesis

(2009) Jian-Min Chen et al.   Annual Review of Genomics and Human Genetics

Alcohol Consumption, Cigarette Smoking, and the Risk of Recurrent Acute and Chronic Pancreatitis

(2009) Dhiraj Yadav   ARCHIVES OF INTERNAL MEDICINE

TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling

(2009) J. Mankertz et al.   CELL AND TISSUE RESEARCH

Sex chromosomes and genetic association studies

(2009) David G Clayton   Genome Medicine

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS

The density of small tight junction pores varies among cell types and is increased by expression of claudin-2

(2008) C. M. Van Itallie et al.   JOURNAL OF CELL SCIENCE

Multicenter Approach to Recurrent Acute and Chronic Pancreatitis in the United States: The North American Pancreatitis Study 2 (NAPS2)

(2008) David C. Whitcomb et al.   PANCREATOLOGY

Acute edematous and necrotic pancreatitis in a porcine model

(2008) Sanna Meriläinen et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Trypsinogen Copy Number Mutations in Patients With Idiopathic Chronic Pancreatitis

(2007) Emmanuelle Masson et al.   Clinical Gastroenterology and Hepatology