An aza-Michael addition protocol to fluoroalkylated β-amino acid derivatives and enantiopure trifluoromethylated N-heterocycles

Synthesis of Carbocyclic and Heterocyclic β-Aminocarboxylic Acids

(2013) Loránd Kiss et al.   CHEMICAL REVIEWS

Recent Developments in the Synthesis of Fluorine-Containingβ-Amino Acids andβ-Lactams

(2013) Daizong Lin et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Cascade Sulfa-Michael/Aldol Reaction of β,β-Disubstituted Enones: Enantioselective Synthesis of Tetrahydrothiophenes with a Trifluoromethylated Quaternary Center

(2013) Yu Su et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Mannich reaction between (S)-N-(tert-butanesulfinyl)-3,3,3-trifluoroacetaldimine and malonic acid derivatives. Stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids

(2013) Norio Shibata et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions

(2013) Yingle Liu et al.   TETRAHEDRON LETTERS

Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study

(2013) Louis C. Morrill et al.   Chemical Science

Advances and Applications in Organocatalytic Asymmetric aza-Michael Addition

(2012) Jun Wang et al.   ChemCatChem

Organic base-catalyzed stereodivergent synthesis of (R)- and (S)-3-amino-4,4,4-trifluorobutanoic acids

(2012) Norio Shibata et al.   CHEMICAL COMMUNICATIONS

Catalytic Synthesis of Optically Active β-Amino Acid Derivatives

(2012) Pinaki S. Bhadury et al.   CURRENT ORGANIC SYNTHESIS

Enantiopure Trifluoromethylated β3,3-Amino Acids: Synthesis by Asymmetric Reformatsky Reaction with Stable Analogues of Trifluoromethyl N-tert-Butanesulfinylketoimines and Incorporation into α/β-Peptides

(2012) Fabienne Grellepois   JOURNAL OF ORGANIC CHEMISTRY

Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis

(2012) Junming Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances in the Synthesis of Fluorinated Amino Acids

(2011) Xiao-Long Qiu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric synthesis of chiral trifluoromethylated heliotridane via highly catalytic asymmetric Friedel–Crafts alkylation with β-trifluoromethylated acrylates and pyrroles

(2011) Yiyong Huang et al.   NEW JOURNAL OF CHEMISTRY

Enantioselective Synthesis of Trifluoromethyl-Substituted 2-Isoxazolines: Asymmetric Hydroxylamine/Enone Cascade Reaction

(2010) Kazutaka Matoba et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Trifluoroacetaldehyde: A useful industrial bulk material for the synthesis of trifluoromethylated amino compounds

(2010) Hideyuki Mimura et al.   JOURNAL OF FLUORINE CHEMISTRY

Enantioselective Friedel−Crafts Reaction of β-Trifluoromethylated Acrylates with Pyrroles and Its Application to the Synthesis of Trifluorinated Heliotridane

(2010) Yiyong Huang et al.   ORGANIC LETTERS

Highly enantio- and diastereoselective synthesis of α-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

(2009) Peng Li et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Asymmetric Aza-Michael Additions

(2009) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective electrophilic trifluoromethylation of β-keto esters with Umemoto reagents induced by chiral nonracemic guanidines

(2009) Shun Noritake et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A New Strategy for the Synthesis of Optically Pure β-Fluoroalkyl β-Amino Acid Derivatives

(2009) Santos Fustero et al.   ORGANIC LETTERS

Recent Advances in Stereoselective Synthesis and Application of β-Amino Acids

(2009) Brad E. Sleebs et al.   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

A practical method to access enantiopure β-perfluoroalkyl-β-amino acids: diastereoselective reduction of cyclic enamino-esters

(2009) Yasuhiro Ishida et al.   TETRAHEDRON LETTERS