Asymmetric synthesis of chiral trifluoromethylated heliotridane via highly catalytic asymmetric Friedel–Crafts alkylation with β-trifluoromethylated acrylates and pyrroles

Asymmetric Friedel-Crafts Reaction of Indoles with Ethyl Trifluoropyruvate Using a Copper(I)-Bisoxazolidine Catalyst

(2011) Christian Wolf et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Organocatalytic Synthesis of Fluorinated Molecules

(2011) Guillem Valero et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Friedel−Crafts Alkylation of Indoles with Trifluoroethylidene Malonates by Copper−Bis(oxazoline) Complexes: Construction of Trifluoromethyl-Substituted Stereogenic Tertiary Carbon Center

(2011) Lele Wen et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalyzed Regio- and Enantioselective Allylic Trifluoromethylation of Morita–Baylis–Hillman Adducts Using Ruppert–Prakash Reagent

(2011) Tatsuya Furukawa et al.   ORGANIC LETTERS

Enantioselective Organocatalytic Synthesis of Quaternary α-Amino Acids Bearing a CF3Moiety

(2011) Ralph Husmann et al.   ORGANIC LETTERS

Highly Enantioselective Zinc-Catalyzed Friedel-Crafts Alkylation of Indoles with Ethyl Trifluoropyruvate

(2010) Yonghai Hui et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Brønsted Acid-Catalyzed Enantioselective Friedel-Crafts Reaction of 4,7-Dihydroindoles with Trifluoromethyl Ketones

(2010) Teng Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Organofluorine Chemistry: Taking the Next Steps

(2010) Antonio Togni   ADVANCED SYNTHESIS & CATALYSIS

Combination Catalysis in Enantioselective Trifluoromethylation

(2010) Yan Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

On the Reach of Chemical Synthesis: Creation of a Mini-Pipeline from an Academic Laboratory

(2010) Rebecca M. Wilson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Synthesis of Functionalized Indoles with a Trifluoromethyl-Substituted Stereogenic Tertiary Carbon Atom Through an Enantioselective Friedel-Crafts Alkylation with β-Trifluoromethyl-α,β-enones

(2010) Gonzalo Blay et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Friedel-Crafts Alkylation of Indoles, Pyrroles, and Furans with Trifluoropyruvate Catalyzed by Chiral Phosphoric Acid

(2010) Wataru Kashikura et al.   Chemistry-An Asian Journal

Stereoselective Construction of an Asymmetric Carbon Center Possessing a Trifluoromethyl Group

(2010) Tsutomu Konno   CURRENT ORGANIC SYNTHESIS

Organocatalyzed Asymmetric Friedel-Crafts Reactions

(2010) Vincent Terrasson et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Productive Merger of Iodonium Salts and Organocatalysis: A Non-photolytic Approach to the Enantioselective α-Trifluoromethylation of Aldehydes

(2010) Anna E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Friedel–Crafts alkylation of indole derivatives catalyzed by new Yb(OTf)3-pyridylalkylamine complexes as chiral Lewis acids

(2010) Guillaume Grach et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Friedel−Crafts Reaction of β-Trifluoromethylated Acrylates with Pyrroles and Its Application to the Synthesis of Trifluorinated Heliotridane

(2010) Yiyong Huang et al.   ORGANIC LETTERS

Enantioselective Gold-Catalyzed Allylic Alkylation of Indoles with Alcohols: An Efficient Route to Functionalized Tetrahydrocarbazoles

(2009) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine & chirality: how to create a nonracemic stereogenic carbon–fluorine centre?

(2009) Dominique Cahard et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric Friedel-Crafts Reaction of 4,7-Dihydroindoles with Nitroolefins by Chiral Brønsted Acids under Low Catalyst Loading

(2009) Yi-Fei Sheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

A DBFOX-Ph-Based Combinatorial Catalyst for Enantioselective Fluorination of Aryl Acetyl and 3-Butenoyl Thiazolidinones

(2009) Dhande Sudhakar Reddy et al.   Chemistry-An Asian Journal

Chiral Brønsted-Acid-Catalyzed Enantioselective Arylation of Ethyl Trifluoroacetoacetate and Ethyl Trifluoropyruvate

(2009) Jing Nie et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Benchmark and Solvent-Free Preparation of Sulfonium Salt Based Electrophilic Trifluoromethylating Reagents

(2009) Yohan Macé et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric synthesis of fluorine-containing amines, amino alcohols, α- and β-amino acids mediated by chiral sulfinyl group

(2009) Alexander E. Sorochinsky et al.   JOURNAL OF FLUORINE CHEMISTRY

Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

(2009) David A. Nagib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective electrophilic trifluoromethylation of β-keto esters with Umemoto reagents induced by chiral nonracemic guanidines

(2009) Shun Noritake et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent advances in enantioselective trifluoromethylation reactions

(2009) Norio Shibata et al.   TETRAHEDRON-ASYMMETRY

Highly Enantioselective Friedel-Crafts Reaction of 4,7-Dihydroindoles with β,γ-Unsaturated α-Keto Esters by Chiral Brønsted Acids

(2008) Mi Zeng et al.   ADVANCED SYNTHESIS & CATALYSIS

A Dynamic Kinetic Asymmetric Transformation in the α-Hydroxylation of Racemic Malonates and Its Application to Biologically Active Molecules

(2008) Dhande Sudhakar Reddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Friedel−Crafts Alkylation ReactionsCopper Showed the Way

(2008) Thomas B. Poulsen et al.   CHEMICAL REVIEWS

Highly Enantioselective Friedel–Crafts Reaction of 4,7-Dihydroindoles with Imines by Chiral Phosphoric Acids: Facile Access to 2-Indolyl Methanamine Derivatives

(2008) Qiang Kang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Friedel−Crafts Alkylation of Pyrroles with Nitroalkenes Using a Dinuclear Zinc Catalyst

(2008) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Triflic Acid-Catalyzed Highly Stereoselective Friedel−Crafts Aminoalkylation of Indoles and Pyrroles

(2008) Mohammed Abid et al.   ORGANIC LETTERS

Enantioselective Zirconium-Catalyzed Friedel−Crafts Alkylation of Pyrrole with Trifluoromethyl Ketones

(2008) Gonzalo Blay et al.   ORGANIC LETTERS

A first high enantiocontrol of an asymmetric tertiary carbon center attached with a fluoroalkyl group via Rh(I)-catalyzed conjugate addition reaction

(2008) Tsutomu Konno et al.   TETRAHEDRON LETTERS

Desymmetrization-like Catalytic Enantioselective Fluorination of Malonates and Its Application to Pharmaceutically Attractive Molecules

(2007) Dhande Sudhakar Reddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS