Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study

SYNTHESIS OF TERT-BUTYL (1S,2S)-2-METHYL-3-OXO-1-PHENYLPROPYLCARBAMATE BY ASYMMETRIC MANNICH REACTION

(2014)   ORGANIC SYNTHESES

Determination of Absolute Configuration of Secondary Alcohols Using Thin-Layer Chromatography

(2013) Alexander J. Wagner et al.   JOURNAL OF ORGANIC CHEMISTRY

NHC-Promoted Asymmetric β-Lactone Formation from Arylalkylketenes and Electron-Deficient Benzaldehydes or Pyridinecarboxaldehydes

(2013) James Douglas et al.   JOURNAL OF ORGANIC CHEMISTRY

Absolute Configuration of Lactams and Oxazolidinones Using Kinetic Resolution Catalysts

(2013) Matthew A. Perry et al.   ORGANIC LETTERS

Kinetic Resolution of Racemic 2-Hydroxy-γ-butyrolactones by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst

(2013) Kenya Nakata et al.   ORGANIC LETTERS

Anhydrides as α,β-unsaturated acyl ammonium precursors: isothiourea-promoted catalytic asymmetric annulation processes

(2013) Emily R. T. Robinson et al.   Chemical Science

Dihydropyridones: Catalytic Asymmetric Synthesis, N- to C-Sulfonyl Transfer, and Derivatizations

(2012) Carmen Simal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidines, isothioureas, and guanidines as nucleophilic catalysts

(2012) James E. Taylor et al.   CHEMICAL SOCIETY REVIEWS

Kinetic Resolution of Racemic Secondary Benzylic Alcohols by the Enantioselective Esterification Using Pyridine-3-carboxylic Anhydride (3-PCA) with Chiral Acyl-Transfer Catalysts

(2012) Isamu Shiina et al.   HELVETICA CHIMICA ACTA

A Diastereoselective, Nucleophile-Promoted Aldol-Lactonization of Ketoacids Leading to Bicyclic-β-Lactones

(2012) Gang Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Kinetic Resolution of Secondary Alcohols Using Amidine-Based Catalysts

(2012) Ximin Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Oxyanion Steering and CH−π Interactions as Key Elements in an N-Heterocyclic Carbene-Catalyzed [4 + 2] Cycloaddition

(2012) Scott E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic, Enantioselective N-Acylation of Lactams and Thiolactams Using Amidine-Based Catalysts

(2012) Xing Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric α-amination of carboxylic acids using isothioureas

(2012) Louis C. Morrill et al.   Chemical Science

Total Synthesis of (+)-Omphadiol

(2011) Gang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonenzymatic Dynamic Kinetic Resolution of α-(Arylthio)- and α-(Alkylthio)alkanoic Acids

(2011) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kinetic Resolution of Racemic 1-Heteroarylalkanols by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-transfer Catalyst

(2011) Isamu Shiina et al.   CHEMISTRY LETTERS

Isothiourea-Catalysed Asymmetric C-Acylation of Silyl Ketene Acetals

(2011) Philip A. Woods et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Catalytic Properties of 4-Aryl-2,3-dihydro-4H-pyrimido[2,3-b]benzothiazoles for Asymmetric Acyl or Carboxyl Group Transfer Reactions

(2011) Baby Viswambharan et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

(2011) Dorine Belmessieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution ofN-Acyl-β-Lactams via Benzotetramisole-Catalyzed Enantioselective Alcoholysis

(2011) Valentina D. Bumbu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Bifunctional to Trifunctional (Tricomponent Nucleophile–Transition Metal–Lewis Acid) Catalysis: The Catalytic, Enantioselective α-Fluorination of Acid Chlorides

(2011) Jeremy Erb et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic base effects in NHC promoted O- to C-carboxyl transfer; chemoselectivity profiles, mechanistic studies and domino catalysis

(2011) Craig D. Campbell et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Determination of Absolute Configuration Using Kinetic Resolution Catalysts

(2011) Alexander J. Wagner et al.   ORGANIC LETTERS

A convenient method for the kinetic resolution of racemic 2-hydroxyalkanoates using diphenylacetic anhydride (DPHAA) and a chiral acyl-transfer catalyst

(2011) Kenya Nakata et al.   TETRAHEDRON-ASYMMETRY

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi- and Tricyclic β-Lactones and Topology-Morphing Transformations

(2010) Carolyn A. Leverett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

(2010) Norio Shibata et al.   Beilstein Journal of Organic Chemistry

A1,3-strain enabled retention of chirality during bis-cyclization of β-ketoamides: total synthesis of (−)-salinosporamide A and (−)-homosalinosporamide A

(2010) Henry Nguyen et al.   CHEMICAL COMMUNICATIONS

α-Aroyloxyaldehydes: scope and limitations as alternatives to α-haloaldehydes for NHC-catalysed redox transformations

(2010) Kenneth B. Ling et al.   CHEMICAL COMMUNICATIONS

NHC-Mediated Chlorination of Unsymmetrical Ketenes: Catalysis and Asymmetry

(2010) James Douglas et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (−)-Salinosporamide A, (−)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-cyclizations

(2010) Henry Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

The Productive Merger of Iodonium Salts and Organocatalysis: A Non-photolytic Approach to the Enantioselective α-Trifluoromethylation of Aldehydes

(2010) Anna E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Ring Opening of Epoxides by Fluoride Anion Promoted by a Cooperative Dual-Catalyst System

(2010) Julia A. Kalow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution of Racemic α-Arylalkanoic Acids with Achiral Alcohols via the Asymmetric Esterification Using Carboxylic Anhydrides and Acyl-Transfer Catalysts

(2010) Isamu Shiina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure-enantioselectivity effects in 3,4-dihydropyrimido[2,1-b]benzothiazole-based isothioureas as enantioselective acylation catalysts

(2010) Dorine Belmessieri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Per(poly)fluoroalkanesulfinamides assisted diastereoselective three-component inverse-electron-demand aza Diels–Alder reaction

(2010) Peng Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Isothiourea-Mediated StereoselectiveC-Acylation of Silyl Ketene Acetals

(2010) Philip A. Woods et al.   ORGANIC LETTERS

Benzotetramisole-Catalyzed Dynamic Kinetic Resolution of Azlactones

(2010) Xing Yang et al.   ORGANIC LETTERS

Double Diastereoselective, Nucleophile-Catalyzed Aldol Lactonizations (NCAL) Leading to β-Lactone Fused Carbocycles and Extensions to β-Lactone Fused Tetrahydrofurans

(2010) Kay A. Morris et al.   ORGANIC LETTERS

Cinchona Alkaloid-Catalyzed Asymmetric Trifluoromethylation of Alkynyl Ketones with Trimethylsilyl Trifluoromethane

(2010) Hiroyuki Kawai et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

An effective kinetic resolution of racemic α-arylpropanoic acids, α-arylbutanoic acids, and β-substituted-α-arylpropanoic acids with bis(9-phenanthryl)methanol as a new achiral nucleophile in the asymmetric esterification using carboxylic anhydrides and the acyl-transfer catalyst

(2010) Kenya Nakata et al.   TETRAHEDRON LETTERS

Homobenzotetramisole-Catalyzed Kinetic Resolution of α-Aryl-, α-Aryloxy-, and α-Arylthioalkanoic Acids

(2009) Xing Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Heterocyclic Carbene-Mediated Enantioselective Addition of Phenols to Unsymmetrical Alkylarylketenes

(2009) Carmen Concellón et al.   ADVANCED SYNTHESIS & CATALYSIS

Effects of Methyl Substituents on the Activity and Enantioselectivity of Homobenzotetramisole-Based Catalysts in the Kinetic Resolution of Alcohols

(2009) Yuhua Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Isothiourea-Catalyzed Enantioselective Carboxy Group Transfer

(2009) Caroline Joannesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantio- and diastereoselective synthesis of α-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

(2009) Peng Li et al.   CHEMICAL COMMUNICATIONS

Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst

(2009) Isamu Shiina et al.   CHEMISTRY-A EUROPEAN JOURNAL

2,2-Disubstituted Propionic Anhydrides: Effective Coupling Reagents for the Kinetic Resolution of Secondary Benzylic Alcohols Using BTM

(2009) Isamu Shiina et al.   HETEROCYCLES

An Effective Kinetic Resolution of Racemic Secondary Benzylic Alcohols Using 3-Pyridinecarboxylic Anhydride and a Chiral Acyl-Transfer Catalyst in the Absence of Tertiary Amine

(2009) Isamu Shiina et al.   HETEROCYCLES

Synthesis of novel C2-symmetric chiral crown ethers and their application to enantioselective trifluoromethylation of aldehydes and ketones

(2009) Hiroyuki Kawai et al.   JOURNAL OF FLUORINE CHEMISTRY

Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

(2009) David A. Nagib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective electrophilic trifluoromethylation of β-keto esters with Umemoto reagents induced by chiral nonracemic guanidines

(2009) Shun Noritake et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Synthesis of β-Trifluoromethyl-β-lactones via NHC-Catalyzed Ketene−Ketone Cycloaddition Reactions

(2009) Xiao-Na Wang et al.   ORGANIC LETTERS

Nonenzymatic kinetic resolution of racemic 2,2,2-trifluoro-1-aryl ethanol via enantioselective acylation

(2009) Qing Xu et al.   TETRAHEDRON

Catalytic, asymmetric reactions of ketenes and ketene enolates

(2009) Daniel H. Paull et al.   TETRAHEDRON

Cinchona alkaloid-derived quaternary ammonium salt combined with NaH: a facile catalyst system for the asymmetric trifluoromethylation of ketones

(2009) Xiaolei Hu et al.   TETRAHEDRON LETTERS

Highly Enantioselective Organocatalytic Carbonyl-Ene Reaction with Strongly Acidic, Chiral Brønsted Acids as Efficient Catalysts

(2008) Magnus Rueping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tandem multi-step synthesis of C-carboxyazlactones promoted by N-heterocyclic carbenes

(2008) Craig D. Campbell et al.   CHEMICAL COMMUNICATIONS

Mild electrophilic trifluoromethylation of secondary and primary aryl- and alkylphosphines using hypervalent iodine(iii)–CF3 reagents

(2008) Patrick Eisenberger et al.   CHEMICAL COMMUNICATIONS

Enantioselective organocatalyzed Henry reaction with fluoromethyl ketones

(2008) Marco Bandini et al.   CHEMICAL COMMUNICATIONS

Recent Advances in Electrophilic CF3-Transfer Using Hypervalent Iodine(III) Reagents

(2008) Iris Kieltsch et al.   CHIMIA

Kinetic Resolution of Racemic Carboxylic Acids Using Achiral Alcohols by the Promotion of Benzoic Anhydrides and Tetramisole Derivatives: Production of Chiral Nonsteroidal Anti-Inflammatory Drugs and Their Esters

(2008) Isamu Shiina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Fluorinated Johnson Reagent for Transfer-Trifluoromethylation to Carbon Nucleophiles

(2008) Shun Noritake et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Probing the Efficiency of N-Heterocyclic Carbene PromotedO- to C-Carboxyl Transfer of Oxazolyl Carbonates

(2008) Jennifer E. Thomson et al.   JOURNAL OF ORGANIC CHEMISTRY

Reactivity of a 10-I-3 Hypervalent Iodine Trifluoromethylation Reagent With Phenols

(2008) Kyrill Stanek et al.   JOURNAL OF ORGANIC CHEMISTRY

Concise Synthesis of Spirocyclic, Bridged γ-Butyrolactones via Stereospecific, Dyotropic Rearrangements of β-Lactones Involving 1,2-Acyl and δ-Lactone Migrations

(2008) Vikram C. Purohit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amidine catalysed O- to C-carboxyl transfer of heterocyclic carbonate derivatives

(2008) Caroline Joannesse et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic carbene catalysed β-lactam synthesis

(2008) Nicolas Duguet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Homobenzotetramisole:  An Effective Catalyst for Kinetic Resolution of Aryl-Cycloalkanols

(2008) Vladimir B. Birman et al.   ORGANIC LETTERS

Organocatalytic enantioselective Friedel–Crafts alkylation of simple phenols with trifluoropyruvate

(2008) Jun-Ling Zhao et al.   TETRAHEDRON LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS