Asymmetric anti-Mannich reactions in continuous flow

Asymmetric Carbon-Carbon Bond Formation under Continuous-Flow Conditions with Chiral Heterogeneous Catalysts

(2013) Tetsu Tsubogo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry

(2013) Volker Hessel et al.   ChemSusChem

Stereoselective organic reactions promoted by immobilized chiral catalysts in continuous flow systems

(2013) Alessandra Puglisi et al.   GREEN CHEMISTRY

Recent Advances in Asymmetric Catalysis in Flow

(2013) Dongbo Zhao et al.   ACS Catalysis

A Polystyrene-Supported, Highly Recyclable Squaramide Organocatalyst for the Enantioselective Michael Addition of 1,3-Dicarbonyl Compounds to β-Nitrostyrenes

(2012) Pinar Kasaplar et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric α-Amination of Aldehydes Catalyzed by PS-Diphenylprolinol Silyl Ethers: Remediation of Catalyst Deactivation for Continuous Flow Operation

(2012) Xinyuan Fan et al.   ADVANCED SYNTHESIS & CATALYSIS

A Solid-Supported Organocatalyst for Continuous-Flow Enantioselective Aldol Reactions

(2012) Carles Ayats et al.   ChemSusChem

Highly efficient asymmetric anti-Mannich reactions of carbonyl compounds with N-carbamoyl imines catalyzed by amino-thiourea organocatalysts

(2012) Jiuzhi Gao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A highly active organocatalyst for the asymmetric α-aminoxylation of aldehydes and α-hydroxylation of ketones

(2012) Xinyuan Fan et al.   RSC Advances

Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline

(2011) Xacobe C Cambeiro et al.   Beilstein Journal of Organic Chemistry

Ten key issues in modern flow chemistry

(2011) Jens Wegner et al.   CHEMICAL COMMUNICATIONS

Cross-coupling in flow

(2011) Timothy Noël et al.   CHEMICAL SOCIETY REVIEWS

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

chiral ionic liquid/esi-ms methodology as an efficient tool for the study of transformations of supported organocatalysts: deactivation pathways of jørgensen-hayashi-type catalysts in asymmetric michael reactions

(2011) Oleg V. Maltsev et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Active Organocatalysts for Asymmetric anti-Mannich Reactions

(2011) Rafael Martín-Rapún et al.   CHEMISTRY-A EUROPEAN JOURNAL

A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles

(2011) Catherine J. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Controlling Stereoselectivity in the Aminocatalytic Enantioselective Mannich Reaction of Aldehydes with In Situ Generated N-Carbamoyl Imines

(2010) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

A 4-Hydroxypyrrolidine-Catalyzed Mannich Reaction of Aldehydes: Control ofanti-Selectivity by Hydrogen Bonding Assisted by Brønsted Acids

(2010) Enrique Gómez-Bengoa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Polymer-Supported Chiral Organocatalysts: Synthetic Strategies for the Road Towards Affordable Polymeric Immobilization

(2010) Tor E. Kristensen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Enantio- and Diastereoselective Mannich Reactions of Glycine Schiff Bases within situGeneratedN-Boc-imines Catalyzed by a Cinchona Alkaloid Thiourea

(2010) Haile Zhang et al.   ORGANIC LETTERS

Homo- and heterogeneous organocatalysis: enantioselective Mannich addition of ketones to endocyclic carbon–nitrogen double bonds

(2010) Knut Schulz et al.   TETRAHEDRON

4-Aminothiourea Prolinoltert-Butyldiphenylsilyl Ether: A Chiral Secondary Amine-Thiourea as Organocatalyst for Enantioselectiveanti-Mannich Reactions

(2009) Hui Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric Mannich Reactions of N-Boc-Protected Imines

(2009) Taichi Kano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5-(Pyrrolidin-2-yl)tetrazole-Catalyzed Aldol and Mannich Reactions: Acceleration and Lower Catalyst Loading in a Continuous-Flow Reactor

(2009) Arjan Odedra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Mannich Reaction of Fluorinated Ketoesters with a Tryptophan-Derived Bifunctional Thiourea Catalyst

(2009) Xiao Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic asymmetric direct Mannich reaction: a powerful tool for the synthesis of α,β-diamino acids

(2009) Ramón Gómez Arrayás et al.   CHEMICAL SOCIETY REVIEWS

A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetricanti-Selective Mannich Reactions andsyn-Selective Cross-Aldol Reactions

(2009) Taichi Kano et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Solid-Supported Organocatalyst for Highly Stereoselective, Batch, and Continuous-Flow Mannich Reactions

(2009) Esther Alza et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Highly Active Catalyst for Huisgen 1,3-Dipolar Cycloadditions Based on the Tris(triazolyl)methanol−Cu(I) Structure

(2009) Salih Özçubukçu et al.   ORGANIC LETTERS

Aminocatalytic Enantioselectiveanti-Mannich Reaction of Aldehydes with In Situ GeneratedN-Cbz andN-Boc Imines

(2008) Chiara Gianelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supported proline and proline-derivatives as recyclable organocatalysts

(2008) Michelangelo Gruttadauria et al.   CHEMICAL SOCIETY REVIEWS

Organocatalytic Enantioselective Mannich-Type Reaction of Phosphorus Ylides:  Synthesis of ChiralN-Boc-β-Amino-α-methylene Carboxylic Esters

(2008) Yan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

3-Trifluoromethanesulfonamido-pyrrolidine:  A General Organocatalyst foranti-Selective Mannich Reactions

(2008) Mickael Pouliquen et al.   ORGANIC LETTERS

Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation

(2007) Kim Alfonsi et al.   GREEN CHEMISTRY

Catalysis of 3-Pyrrolidinecarboxylic Acid and Related Pyrrolidine Derivatives in Enantioselectiveanti-Mannich-Type Reactions:  Importance of the 3-Acid Group on Pyrrolidine for Stereocontrol

(2007) Haile Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward an Artificial Aldolase

(2007) Daniel Font et al.   ORGANIC LETTERS

anti-Selective direct asymmetric Mannich reactions catalyzed by chiral pyrrolidine-based amino sulfonamides

(2007) Taichi Kano et al.   TETRAHEDRON