Classical and unconventional pathways of vesicular release in microglia

Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-β Degrading Protease

(2017) Ayelén Bulloj et al.   JOURNAL OF ALZHEIMERS DISEASE

Myeloid microvesicles are a marker and therapeutic target for neuroinflammation

(2012) Claudia Verderio et al.   ANNALS OF NEUROLOGY

Extracellular vesicles - vehicles that spread cancer genes

(2012) Janusz Rak et al.   BIOESSAYS

Wnt3a induces exosome secretion from primary cultured rat microglia

(2012) Claudie Hooper et al.   BMC NEUROSCIENCE

Functions of connexins and large pore channels on microglial cells: The gates to environment

(2012) Thomas Mika et al.   BRAIN RESEARCH

Microglial migration mediated by ATP-induced ATP release from lysosomes

(2012) Ying Dou et al.   CELL RESEARCH

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism

(2012) Flavia Antonucci et al.   EMBO JOURNAL

IL-18 associates to microvesicles shed from human macrophages by a LPS/TLR-4 independent mechanism in response to P2X receptor stimulation

(2012) Sara Gulinelli et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Astrocytes Secrete Exosomes Enriched with Proapoptotic Ceramide and Prostate Apoptosis Response 4 (PAR-4)

(2012) Guanghu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

(2012) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic pathways linking hemostasis and cancer

(2012) Delphine Garnier et al.   THROMBOSIS RESEARCH

Extracellular Membrane Vesicles and Immune Regulation in the Brain

(2012) Chiara Cossetti et al.   Frontiers in Physiology

Microvesicles: Novel Biomarkers for Neurological Disorders

(2012) Elisa Colombo et al.   Frontiers in Physiology

Microglial microvesicle secretion and intercellular signaling

(2012) Elena Turola   Frontiers in Physiology

TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes

(2011) Claudia Verderio et al.   BIOLOGY OF THE CELL

Microvesicles: Messengers and mediators of tumor progression

(2011) Khalid Al-Nedawi et al.   CELL CYCLE

Brain Tumor Microvesicles: Insights into Intercellular Communication in the Nervous System

(2011) Kristan E. van der Vos et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors

(2011) Beiyi Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Increased expression of cystine/glutamate antiporter in multiple sclerosis

(2011) Olatz Pampliega et al.   Journal of Neuroinflammation

Amyloid  -Induced Death in Neurons Involves Glial and Neuronal Hemichannels

(2011) J. A. Orellana et al.   JOURNAL OF NEUROSCIENCE

Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins

(2011) Xin Gan et al.   MOLECULAR BIOLOGY OF THE CELL

Statins in Unconventional Secretion of Insulin-Degrading Enzyme and Degradation of the Amyloid-ß Peptide

(2011) Konstantin Glebov et al.   Neurodegenerative Diseases

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Microglia in the developing brain: from immunity to behaviour

(2010) Timm Schlegelmilch et al.   CURRENT OPINION IN NEUROBIOLOGY

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

(2010) Irfan Y. Tamboli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

(2010) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Orchestration of macrophage polarization

(2009) A. Mantovani et al.   BLOOD

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation Triggers Synaptic Alteration and Degeneration in Experimental Autoimmune Encephalomyelitis

(2009) D. Centonze et al.   JOURNAL OF NEUROSCIENCE

P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation

(2009) T. Trang et al.   JOURNAL OF NEUROSCIENCE

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Differential stimulation of monocytic cells results in distinct populations of microparticles

(2009) M. BERNIMOULIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cystatin C is released in association with exosomes: A new tool of neuronal communication which is unbalanced in Alzheimer's disease

(2009) Roberta Ghidoni et al.   NEUROBIOLOGY OF AGING

Monocyte Derived Microvesicles Deliver a Cell Death Message via Encapsulated Caspase-1

(2009) Anasuya Sarkar et al.   PLoS One

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells

(2008) Walter Nickel et al.   Annual Review of Cell and Developmental Biology

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts

(2008) P. Gonnord et al.   FASEB JOURNAL

P2X7 receptor stimulation in primary cultures of rat spinal microglia induces downregulation of the activity for glutamate transport

(2008) Norimitsu Morioka et al.   GLIA

Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes

(2008) Nicola Hamilton et al.   GLIA

Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS

(2008) Alexander H. de Haas et al.   GLIA

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

(2008) Matteo Bergami et al.   JOURNAL OF CELL BIOLOGY

Glial connexins and gap junctions in CNS inflammation and disease

(2008) Tammy Kielian   JOURNAL OF NEUROCHEMISTRY

Identification of a vesicular nucleotide transporter

(2008) K. Sawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

New structures help the modeling of toxic amyloidß ion channels

(2008) Hyunbum Jang et al.   TRENDS IN BIOCHEMICAL SCIENCES