Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells
Authors
Keywords
-
Journal
GENES AND IMMUNITY
Volume 13, Issue 1, Pages 1-13
Publisher
Springer Nature
Online
2011-11-03
DOI
10.1038/gene.2011.77
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF- -Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression
- (2014) S. Xiao et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Foxp3+CD4+CD25+ Regulatory T Cells Induced by IL-2 and TGF- Are Resistant to Th17 Conversion by IL-6
- (2014) S. G. Zheng et al. JOURNAL OF IMMUNOLOGY
- Epigenetic Regulation of Foxp3 Expression in Regulatory T Cells by DNA Methylation
- (2014) G. Lal et al. JOURNAL OF IMMUNOLOGY
- Isoform-Specific Inhibition of ROR -Mediated Transcriptional Activation by Human FOXP3
- (2014) J. Du et al. JOURNAL OF IMMUNOLOGY
- Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease
- (2011) K. L. Hippen et al. AMERICAN JOURNAL OF TRANSPLANTATION
- JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation
- (2011) Jun-Seock Son et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MicroRNA control of lymphocyte differentiation and function
- (2011) Laura Belver et al. CURRENT OPINION IN IMMUNOLOGY
- Interleukin-12 Converts Foxp3+ Regulatory T Cells to Interferon–γ-Producing Foxp3+ T Cells That Inhibit Colitis
- (2011) Ting Feng et al. GASTROENTEROLOGY
- Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation
- (2011) Ashutosh Chaudhry et al. IMMUNITY
- Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells
- (2011) Hozefa S. Bandukwala et al. IMMUNITY
- An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells
- (2011) Yunqi Wang et al. IMMUNITY
- Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth
- (2011) Soraya Zorro Manrique et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease
- (2011) Jeffrey VanValkenburgh et al. JOURNAL OF EXPERIMENTAL MEDICINE
- miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice
- (2011) Mark P. Boldin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Noncanonical K27-Linked Polyubiquitination of TIEG1 Regulates Foxp3 Expression and Tumor Growth
- (2011) D.-J. Peng et al. JOURNAL OF IMMUNOLOGY
- Functional Plasticity of Antigen-Specific Regulatory T Cells in Context of Tumor
- (2011) C. Addey et al. JOURNAL OF IMMUNOLOGY
- IL-2 Controls the Stability of Foxp3 Expression in TGF- -Induced Foxp3+ T Cells In Vivo
- (2011) Q. Chen et al. JOURNAL OF IMMUNOLOGY
- Notch3 and Canonical NF- B Signaling Pathways Cooperatively Regulate Foxp3 Transcription
- (2011) A. Barbarulo et al. JOURNAL OF IMMUNOLOGY
- Multipotent Mesenchymal Stromal Cells Express FoxP3
- (2011) Mikael Sundin et al. JOURNAL OF IMMUNOTHERAPY
- Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft Survival
- (2011) U. H. Beier et al. MOLECULAR AND CELLULAR BIOLOGY
- Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
- (2011) Xiang-Ping Yang et al. NATURE IMMUNOLOGY
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
- (2011) Margarita Dominguez-Villar et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg
- (2011) Mayuko Yamamoto et al. PLoS One
- Foxp3 Interacts with c-Rel to Mediate NF-κB Repression
- (2011) Louiza Loizou et al. PLoS One
- Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1
- (2011) Jorg van Loosdregt et al. PLoS One
- Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity
- (2011) K. L. Hippen et al. Science Translational Medicine
- Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
- (2010) C. G. Brunstein et al. BLOOD
- Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
- (2010) Dan R. Littman et al. CELL
- Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses
- (2010) Li-Fan Lu et al. CELL
- CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism
- (2010) Marzia Soligo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases
- (2010) Zaruhi Hovhannisyan et al. GASTROENTEROLOGY
- Regulation of MicroRNA Expression and Abundance during Lymphopoiesis
- (2010) Stefan Kuchen et al. IMMUNITY
- Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I
- (2010) Lili Xu et al. IMMUNITY
- Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice
- (2010) Madhav D. Sharma et al. IMMUNITY
- MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development
- (2010) Ryan M. O'Connell et al. IMMUNITY
- Foxo Transcription Factors Control Regulatory T Cell Development and Function
- (2010) Yann M. Kerdiles et al. IMMUNITY
- Valproate Treatment of Human Cord Blood CD4-positive Effector T Cells Confers on Them the Molecular Profile (MicroRNA Signature and FOXP3 Expression) of Natural Regulatory CD4-positive Cells through Inhibition of Histone Deacetylase
- (2010) Hussein Fayyad-Kazan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
- (2010) Yohsuke Harada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Ets-1 transcription factor controls the development and function of natural regulatory T cells
- (2010) Enguerran Mouly et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Myelin-Reactive, TGF- -Induced Regulatory T Cells Can Be Programmed To Develop Th1-Like Effector Function but Remain Less Proinflammatory Than Myelin-Reactive Th1 Effectors and Can Suppress Pathogenic T Cell Clonal Expansion In Vivo
- (2010) R. A. O'Connor et al. JOURNAL OF IMMUNOLOGY
- Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF-
- (2010) M. Monteiro et al. JOURNAL OF IMMUNOLOGY
- Small RNAs Guide Hematopoietic Cell Differentiation and Function
- (2010) F. Navarro et al. JOURNAL OF IMMUNOLOGY
- RORC2 Is Involved in T Cell Polarization through Interaction with the FOXP3 Promoter
- (2010) S. Burgler et al. JOURNAL OF IMMUNOLOGY
- An Intrinsic Mechanism Predisposes Foxp3-Expressing Regulatory T Cells to Th2 Conversion In Vivo
- (2010) Y. Wang et al. JOURNAL OF IMMUNOLOGY
- IL-1 -Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-Producing Cells
- (2010) L. Li et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu
- (2010) X. Zhou et al. JOURNAL OF IMMUNOLOGY
- IL-17- and IFN- -Secreting Foxp3+ T Cells Infiltrate the Target Tissue in Experimental Autoimmunity
- (2010) M. Esposito et al. JOURNAL OF IMMUNOLOGY
- Dicer Insufficiency and MicroRNA-155 Overexpression in Lupus Regulatory T Cells: An Apparent Paradox in the Setting of an Inflammatory Milieu
- (2010) A. A. Divekar et al. JOURNAL OF IMMUNOLOGY
- Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
- (2010) Julia K. Polansky et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Altered miRNA expression in T regulatory cells in course of multiple sclerosis
- (2010) Giuseppe De Santis et al. JOURNAL OF NEUROIMMUNOLOGY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
- (2010) Sihem Cheloufi et al. NATURE
- Mammalian microRNAs predominantly act to decrease target mRNA levels
- (2010) Huili Guo et al. NATURE
- Control of the differentiation of regulatory T cells and TH17 cells by the DNA-binding inhibitor Id3
- (2010) Takashi Maruyama et al. NATURE IMMUNOLOGY
- Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
- (2010) Arito Yamane et al. NATURE IMMUNOLOGY
- Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells
- (2010) Weiming Ouyang et al. NATURE IMMUNOLOGY
- The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells
- (2010) Guangwei Liu et al. NATURE IMMUNOLOGY
- T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker
- (2010) Jing Liu et al. PLoS One
- Characterization of Protective Human CD4+CD25+ FOXP3+ Regulatory T Cells Generated with IL-2, TGF-β and Retinoic Acid
- (2010) Ling Lu et al. PLoS One
- Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis
- (2010) J.-S. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Ligase PIAS1 Restricts Natural Regulatory T Cell Differentiation by Epigenetic Repression
- (2010) B. Liu et al. SCIENCE
- Stability of the Regulatory T Cell Lineage in Vivo
- (2010) Y. P. Rubtsov et al. SCIENCE
- A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
- (2010) D. Cifuentes et al. SCIENCE
- Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
- (2009) J. van Loosdregt et al. BLOOD
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- The development and function of regulatory T cells
- (2009) Creg J. Workman et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients
- (2009) Renata Hezova et al. CELLULAR IMMUNOLOGY
- IL-1β and IL-2 convert human Treg into TH17 cells
- (2009) Florence Deknuydt et al. CLINICAL IMMUNOLOGY
- Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation
- (2009) Petra Hoffmann et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression
- (2009) Redouane Rouas et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
- (2009) João H. Duarte et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells
- (2009) Gang Wei et al. IMMUNITY
- Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein
- (2009) Li-Fan Lu et al. IMMUNITY
- Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor
- (2009) Meixiao Long et al. IMMUNITY
- Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection
- (2009) Guillaume Oldenhove et al. IMMUNITY
- Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome
- (2009) Qingguo Ruan et al. IMMUNITY
- Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+inducible regulatory T cells
- (2009) Sven Klunker et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of cAMP Degradation Improves Regulatory T Cell-Mediated Suppression
- (2009) T. Bopp et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells
- (2009) S. Kohlhaas et al. JOURNAL OF IMMUNOLOGY
- Direct activation of protein kinases by unanchored polyubiquitin chains
- (2009) Zong-Ping Xia et al. NATURE
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
- (2009) Ye Zheng et al. NATURE
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
- (2009) Xuyu Zhou et al. NATURE IMMUNOLOGY
- The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR
- (2009) Guangwei Liu et al. NATURE IMMUNOLOGY
- Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells
- (2009) Dipayan Rudra et al. NATURE IMMUNOLOGY
- The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
- (2009) Meghan A Koch et al. NATURE IMMUNOLOGY
- Three Distinct Domains Contribute to Nuclear Transport of Murine Foxp3
- (2009) Wayne W. Hancock et al. PLoS One
- Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
- (2009) Noriko Komatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of IL-17-producing FOXP3+ regulatory T cells in humans
- (2009) K. S. Voo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches
- (2009) M. Tsuji et al. SCIENCE
- Eos Mediates Foxp3-Dependent Gene Silencing in CD4+ Regulatory T Cells
- (2009) F. Pan et al. SCIENCE
- CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
- (2009) A. Chaudhry et al. SCIENCE
- Notch1 and TGF 1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
- (2008) J. B. Samon et al. BLOOD
- Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
- (2008) H. J. P. M. Koenen et al. BLOOD
- Acetylation Is Indispensable for p53 Activation
- (2008) Yi Tang et al. CELL
- Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage
- (2008) Sergei B. Koralov et al. CELL
- Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters
- (2008) Andrea Ventura et al. CELL
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- miR-142-3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA
- (2008) Bo Huang et al. EMBO REPORTS
- DNA methylation controls Foxp3 gene expression
- (2008) Julia K. Polansky et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs
- (2008) Xuexian O. Yang et al. IMMUNITY
- FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity
- (2008) Zhaocai Zhou et al. IMMUNOLOGIC RESEARCH
- Foxp3 Processing by Proprotein Convertases and Control of Regulatory T Cell Function
- (2008) Edwin F. de Zoeten et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT6 Inhibits TGF-β1-mediated Foxp3 Induction through Direct Binding to theFoxp3Promoter, Which Is Reverted by Retinoic Acid Receptor
- (2008) Hiromi Takaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
- (2008) Mark M.W. Chong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dicer-dependent microRNA pathway safeguards regulatory T cell function
- (2008) Adrian Liston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity
- (2008) Xuyu Zhou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms
- (2008) Hai-Feng Ou-Yang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
- (2008) Francisco J. Quintana et al. NATURE
- TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
- (2008) Liang Zhou et al. NATURE
- FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans
- (2008) Peter C. J. Janson et al. PLoS One
- TGF- and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3
- (2008) A. Samanta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started