Role of cellular iron and oxygen in the regulation of HIV-1 infection

Substance Abuse, HIV-1 and Hepatitis

(2016) Nirzari Parikh et al.   CURRENT HIV RESEARCH

Small Molecules Targeted to a Non-Catalytic “RVxF” Binding Site of Protein Phosphatase-1 Inhibit HIV-1

(2012) Tatiana Ammosova et al.   PLoS One

CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90

(2012) Denitra Breuer et al.   Retrovirology

Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR

(2012) Mirai Nakamura et al.   Retrovirology

CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes

(2012) Emmanuelle Wilhelm et al.   Retrovirology

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in US hospital discharge records: a cross-sectional study

(2012) Mehdi Nouraie et al.   SEXUALLY TRANSMITTED INFECTIONS

Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition

(2012) Nadine Czudnochowski et al.   Nature Communications

Sickle Hemoglobin Confers Tolerance to Plasmodium Infection

(2011) Ana Ferreira et al.   CELL

Hemoglobin Directs Macrophage Differentiation and Prevents Foam Cell Formation in Human Atherosclerotic Plaques

(2011) Aloke V. Finn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175

(2011) Tatiana Ammosova et al.   PLoS One

Cyclin-dependent kinase inhibitors: a survey of recent patent literature

(2010) Hervé Galons et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Multiple regulatory mechanisms act in concert to control ferroportin expression and heme iron recycling by macrophages

(2010) C. Beaumont   HAEMATOLOGICA

Expression of a Protein Phosphatase 1 Inhibitor, cdNIPP1, Increases CDK9 Threonine 186 Phosphorylation and Inhibits HIV-1 Transcription

(2010) Tatiana Ammosova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide suppresses HIV-1 replication in human monocytes by protein kinase C-dependent heme oxygenase-1 induction

(2010) Krishnakumar Devadas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription

(2010) Nanhai He et al.   MOLECULAR CELL

HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP

(2010) Bijan Sobhian et al.   MOLECULAR CELL

Iron Chelators of the Di-2-pyridylketone Thiosemicarbazone and 2-Benzoylpyridine Thiosemicarbazone Series Inhibit HIV-1 Transcription: Identification of Novel Cellular Targets--Iron, Cyclin-Dependent Kinase (CDK) 2, and CDK9

(2010) Z. Debebe et al.   MOLECULAR PHARMACOLOGY

Hepcidin induces HIV-1 transcription inhibited by ferroportin

(2010) Min Xu et al.   Retrovirology

Multiple transfusions for sickle cell disease in the Democratic Republic of Congo: The importance of the hepatitis C virus

(2010) S. Batina Agasa et al.   TRANSFUSION CLINIQUE ET BIOLOGIQUE

HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear

(2010) Iván D’Orso et al.   Viruses-Basel

Mortality in HIV infection is independently predicted by host iron status and SLC11A1 and HP genotypes, with new evidence of a gene-nutrient interaction

(2009) Joann M McDermid et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Regulation of serum hepcidin levels in sickle cell disease

(2009) J. J.C. Kroot et al.   HAEMATOLOGICA

Hypoxia or in situ normoxia: The stem cell paradigm

(2009) Zoran Ivanovic   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration

(2009) Sharroya Charles et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Angiogenic and Inflammatory Markers of Cardiopulmonary Changes in Children and Adolescents with Sickle Cell Disease

(2009) Xiaomei Niu et al.   PLoS One

7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development

(2009) M. Barboric et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A

(2009) Mainul Hoque et al.   Retrovirology

Iron Sequestration and Anemia of Inflammation

(2009) Tomas Ganz et al.   SEMINARS IN HEMATOLOGY

9-aminoacridine Inhibition of HIV-1 Tat Dependent Transcription

(2009) Irene Guendel et al.   Virology Journal

Cell Biology of HIV-1 Infection of Macrophages

(2008) Carol A. Carter et al.   Annual Review of Microbiology

The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes

(2008) Andreas Markert et al.   EMBO REPORTS

PP2B and PP1  cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

(2008) R. Chen et al.   GENES & DEVELOPMENT

A La-Related Protein Modulates 7SK snRNP Integrity to Suppress P-TEFb-Dependent Transcriptional Elongation and Tumorigenesis

(2008) Nanhai He et al.   MOLECULAR CELL

Viral infection and iron metabolism

(2008) Hal Drakesmith et al.   NATURE REVIEWS MICROBIOLOGY

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

(2008) B. J. Krueger et al.   NUCLEIC ACIDS RESEARCH

Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease

(2008) Bita Sahaf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated iron stores are associated with HIV disease severity and mortality among postpartum women in Zimbabwe

(2008) R Rawat et al.   PUBLIC HEALTH NUTRITION

Drug 9AA reactivates p21/Waf1 and inhibits HIV-1 progeny formation

(2008) Weilin Wu et al.   Virology Journal

Immune activation and inflammation in HIV-1 infection: causes and consequences

(2007) V Appay et al.   JOURNAL OF PATHOLOGY