Influenza-induced innate immunity: regulators of viral replication, respiratory tract pathology & adaptive immunity

Protective role of interferon-induced Mx GTPases against influenza viruses

(2016) O. HALLER et al.   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

Induction of Proinflammatory Cytokines in Primary Human Macrophages by Influenza A Virus (H5N1) Is Selectively Regulated by IFN Regulatory Factor 3 and p38 MAPK

(2014) K. P. Y. Hui et al.   JOURNAL OF IMMUNOLOGY

Pandemic H1N1 influenza virus causes a stronger inflammatory response than seasonal H1N1 influenza virus in ferrets

(2011) Young Myong Kang et al.   ARCHIVES OF VIROLOGY

Cytokine production by primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1 2009 influenza viruses

(2011) S. Sakabe et al.   JOURNAL OF GENERAL VIROLOGY

Susceptibility to Infection and Inflammatory Response Following Influenza Virus (H1N1, A/PR/8/34) Challenge: Role of Macrophages

(2011) E. Angela Murphy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Tropism and Innate Host Responses of the 2009 Pandemic H1N1 Influenza Virus in ex Vivo and in Vitro Cultures of Human Conjunctiva and Respiratory Tract

(2010) Michael C.W. Chan et al.   AMERICAN JOURNAL OF PATHOLOGY

Host Immune and Apoptotic Responses to Avian Influenza Virus H9N2 in Human Tracheobronchial Epithelial Cells

(2010) Zheng Xing et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Comparison of the Pathology Caused by H1N1, H5N1, and H3N2 Influenza Viruses

(2010) Jeannette Guarner et al.   ARCHIVES OF MEDICAL RESEARCH

Induction of TNF-α in human macrophages by avian and human influenza viruses

(2010) Yuwarat Monteerarat et al.   ARCHIVES OF VIROLOGY

Respiratory epithelial cells in innate immunity to influenza virus infection

(2010) Catherine J. Sanders et al.   CELL AND TISSUE RESEARCH

Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge

(2010) Jacob E. Kohlmeier et al.   IMMUNITY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Mice Lacking Both TNF and IL‐1 Receptors Exhibit Reduced Lung Inflammation and Delay in Onset of Death following Infection with a Highly Virulent H5N1 Virus

(2010) Lucy A. Perrone et al.   JOURNAL OF INFECTIOUS DISEASES

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

(2010) N. A. Jewell et al.   JOURNAL OF VIROLOGY

Genomic Profiling of Tumor Necrosis Factor Alpha (TNF- ) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-  Signaling and Increased Severity of 1918 Pandemic Influenza Virus Infection

(2010) S. E. Belisle et al.   JOURNAL OF VIROLOGY

Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

(2010) M. D. Tate et al.   JOURNAL OF VIROLOGY

Comparison of pro-inflammatory cytokine expression and cellular signal transduction in human macrophages infected with different influenza A viruses

(2010) Janina Geiler et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling

(2010) Danlin Jia et al.   PLoS One

Role of Host Immune Response and Viral Load in the Differential Outcome of Pandemic H1N1 (2009) Influenza Virus Infection in Indian Patients

(2010) Vidya A. Arankalle et al.   PLoS One

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling host responses in ferrets during A/California/07/2009 influenza infection

(2010) Thomas Rowe et al.   VIROLOGY

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription

(2010) Rei-Lin Kuo et al.   VIROLOGY

Profiles of cytokine and chemokine gene expression in human pulmonary epithelial cells induced by human and avian influenza viruses

(2010) WY Lam et al.   Virology Journal

Regulation of autoreactive B cell responses to endogenous TLR ligands

(2009) Ana Maria Avalos et al.   AUTOIMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Viral Genetic Determinants of H5N1 Influenza Viruses That Contribute to Cytokine Dysregulation

(2009) Ka Pun Mok et al.   JOURNAL OF INFECTIOUS DISEASES

Cytokine Profiles Induced by the Novel Swine‐Origin Influenza A/H1N1 Virus: Implications for Treatment Strategies

(2009) Patrick C. Y. Woo et al.   JOURNAL OF INFECTIOUS DISEASES

The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

(2009) R. Billharz et al.   JOURNAL OF VIROLOGY

The NS1 Protein of a Human Influenza Virus Inhibits Type I Interferon Production and the Induction of Antiviral Responses in Primary Human Dendritic and Respiratory Epithelial Cells

(2009) K. Haye et al.   JOURNAL OF VIROLOGY

Pandemic H1N1 2009 Influenza A Virus Induces Weak Cytokine Responses in Human Macrophages and Dendritic Cells and Is Highly Sensitive to the Antiviral Actions of Interferons

(2009) P. Osterlund et al.   JOURNAL OF VIROLOGY

Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages

(2009) Suki M. Y. Lee et al.   PLoS One

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune response to H3N2 and H1N1 influenza virus infection in a human lung organ culture model

(2009) Wenxin Wu et al.   VIROLOGY

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in Humans

(2008) Christine Korteweg et al.   AMERICAN JOURNAL OF PATHOLOGY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Hyperinduction of Cyclooxygenase‐2–Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection

(2008) Suki M. Y. Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Differential Response of Respiratory Dendritic Cell Subsets to Influenza Virus Infection

(2008) X. Hao et al.   JOURNAL OF VIROLOGY

Gene Expression Analysis of Host Innate Immune Responses during Lethal H5N1 Infection in Ferrets

(2008) C. M. Cameron et al.   JOURNAL OF VIROLOGY

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

(2008) Anna Yarilina et al.   NATURE IMMUNOLOGY

Analysis of cytokine secretion from human plasmacytoid dendritic cells infected with H5N1 or low-pathogenicity influenza viruses

(2008) Matthew R. Sandbulte et al.   VIROLOGY

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens