- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting DNA repair pathways for cancer treatment: what’s new?
Authors
Keywords
-
Journal
Future Oncology
Volume 10, Issue 7, Pages 1215-1237
Publisher
Future Medicine Ltd
Online
2014-06-20
DOI
10.2217/fon.14.60
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Is a Potent Inhibitor of ATM- and DNA-PKCs-Mediated DNA Damage Responses
- (2015) Bipasha Mukherjee et al. NEOPLASIA
- Physician-assessed and patient-reported outcome measures in chemotherapy-induced sensory peripheral neurotoxicity: two sides of the same coin
- (2013) P. Alberti et al. ANNALS OF ONCOLOGY
- Current strategies to minimize toxicity of oxaliplatin
- (2013) Raffaele Di Francia et al. ANTI-CANCER DRUGS
- Human Apurinic/Apyrimidinic Endonuclease 1
- (2013) Mengxia Li et al. ANTIOXIDANTS & REDOX SIGNALING
- Neuropathic pain in cancer
- (2013) M.T. Fallon BRITISH JOURNAL OF ANAESTHESIA
- Chemotherapy-induced peripheral neurotoxicity: A critical analysis
- (2013) Susanna B. Park et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy
- (2013) Toru Kono et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Proteasome inhibition induces DNA damage and reorganizes nuclear architecture and protein synthesis machinery in sensory ganglion neurons
- (2013) Ana Palanca et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): A systematic review
- (2013) Janet M. Schloss et al. CLINICAL NUTRITION
- DNA damage response in peripheral nervous system: Coping with cancer therapy-induced DNA lesions
- (2013) Ella W. Englander DNA REPAIR
- PARP inhibitors in cancer therapy: an update
- (2013) Gianluca Papeo et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach
- (2013) Andreas O. Frank et al. JOURNAL OF MEDICINAL CHEMISTRY
- Breaking the Invulnerability of Cancer Stem Cells: Two-Step Strategy to Kill the Stem-like Cell Subpopulation of Multiple Myeloma
- (2013) A. Morgenroth et al. MOLECULAR CANCER THERAPEUTICS
- The Antioxidant Effects of the Flavonoids Rutin and Quercetin Inhibit Oxaliplatin-Induced Chronic Painful Peripheral Neuropathy
- (2013) Maria Isabel Azevedo et al. Molecular Pain
- CHEK again: Revisiting the development of CHK1 inhibitors for cancer therapy
- (2013) S. McNeely et al. PHARMACOLOGY & THERAPEUTICS
- A Novel and Selective Poly (ADP-Ribose) Polymerase Inhibitor Ameliorates Chemotherapy-Induced Painful Neuropathy
- (2013) Lauren E. Ta et al. PLoS One
- DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruption
- (2013) Xin Zhou et al. PLoS One
- Comparison of two chemotherapy-induced peripheral neuropathy measurement approaches in children
- (2013) L. S. Gilchrist et al. SUPPORTIVE CARE IN CANCER
- O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas
- (2013) C-H Fan et al. Cell Death & Disease
- An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development
- (2013) Derek M. van Pel et al. PLoS Genetics
- Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond
- (2013) David Davidson et al. Frontiers in Pharmacology
- DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
- (2012) Mark Kelley et al. Anti-Cancer Agents in Medicinal Chemistry
- Recent Advances in Hsp90 Inhibitors as Antitumor Agents
- (2012) S. Messaoudi et al. Anti-Cancer Agents in Medicinal Chemistry
- Inhibiting homologous recombination for cancer therapy
- (2012) Sophia B. Chernikova et al. CANCER BIOLOGY & THERAPY
- Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
- (2012) J. Murai et al. CANCER RESEARCH
- An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression
- (2012) Mrinal Srivastava et al. CELL
- Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control
- (2012) Sarah E. Golding et al. CELL CYCLE
- Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs
- (2012) Ajay Srinivasan et al. Future Medicinal Chemistry
- Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors
- (2012) Rebeka Sultana et al. INTERNATIONAL JOURNAL OF CANCER
- Mission Therapeutics
- (2012) Ken Garber NATURE BIOTECHNOLOGY
- PARP-1 Inhibitors DPQ and PJ-34 Negatively Modulate Proinflammatory Commitment of Human Glioblastoma Cells
- (2012) Marina Scalia et al. NEUROCHEMICAL RESEARCH
- Homologous recombination and its regulation
- (2012) L. Krejci et al. NUCLEIC ACIDS RESEARCH
- DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy
- (2012) E. M. McNeil et al. NUCLEIC ACIDS RESEARCH
- RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells
- (2012) Brian Budke et al. NUCLEIC ACIDS RESEARCH
- Inhibition of Non-Homologous End Joining Repair Impairs Pancreatic Cancer Growth and Enhances Radiation Response
- (2012) Ying-Hua Li et al. PLoS One
- APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival
- (2012) Angelo A. Cardoso et al. PLoS One
- Virtual Screening and Biological Evaluation of Inhibitors Targeting the XPA-ERCC1 Interaction
- (2012) Khaled H. Barakat et al. PLoS One
- The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling
- (2011) Arvin C. Dar et al. Annual Review of Biochemistry
- Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
- (2011) Komal Jhaveri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination
- (2011) Michele Tavecchio et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Parallel High-Throughput RNA Interference Screens Identify PINK1 as a Potential Therapeutic Target for the Treatment of DNA Mismatch Repair-Deficient Cancers
- (2011) S. A. Martin et al. CANCER RESEARCH
- Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily
- (2011) Susan E. Tsutakawa et al. CELL
- Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit
- (2011) Jonathan P. DiNitto et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation
- (2011) Michael R. Vasko et al. DNA REPAIR
- Repair-specific Functions of Replication Protein A
- (2011) Cathy S. Hass et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Replication protein A promotes 5′→3′ end processing during homology-dependent DNA double-strand break repair
- (2011) Hong Yan et al. JOURNAL OF CELL BIOLOGY
- Inhibition of Homologous Recombination by DNA-Dependent Protein Kinase Requires Kinase Activity, Is Titratable, and Is Modulated by Autophosphorylation
- (2011) J. A. Neal et al. MOLECULAR AND CELLULAR BIOLOGY
- Novel Irreversible Small Molecule Inhibitors of Replication Protein A Display Single-Agent Activity and Synergize with Cisplatin
- (2011) T. M. Neher et al. MOLECULAR CANCER THERAPEUTICS
- Impact of APE1/Ref-1 Redox Inhibition on Pancreatic Tumor Growth
- (2011) M. L. Fishel et al. MOLECULAR CANCER THERAPEUTICS
- Unknown
- (2011) Mary Leung et al. MOLECULAR MEDICINE
- PARP inhibitors stumble in breast cancer
- (2011) Malini Guha NATURE BIOTECHNOLOGY
- Iniparib plus Chemotherapy in Metastatic Triple-Negative Breast Cancer
- (2011) Joyce O'Shaughnessy et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA Polymerase β as a Novel Target for Chemotherapeutic Intervention of Colorectal Cancer
- (2011) Aruna S. Jaiswal et al. PLoS One
- APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
- (2011) Mark R. Kelley et al. Current Molecular Pharmacology
- A review of PARP inhibitors: from bench to bedside
- (2010) C. Underhill et al. ANNALS OF ONCOLOGY
- Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer
- (2010) Rachel Abbotts et al. CANCER TREATMENT REVIEWS
- Homologous recombination in cancer development, treatment and development of drug resistance
- (2010) T. Helleday CARCINOGENESIS
- Hsp90 modulates CAG repeat instability in human cells
- (2010) David Mittelman et al. CELL STRESS & CHAPERONES
- Targeting DNA repair proteins for cancer treatment
- (2010) Gianluca Tell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Functions of disordered regions in mammalian early base excision repair proteins
- (2010) Muralidhar L. Hegde et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Small molecule inhibitors of DNA repair nuclease activities of APE1
- (2010) David M. Wilson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Therapeutic Targeting of the DNA Mismatch Repair Pathway
- (2010) S. A. Martin et al. CLINICAL CANCER RESEARCH
- Perspective on the Pipeline of Drugs Being Developed with Modulation of DNA Damage as a Target
- (2010) R. Plummer CLINICAL CANCER RESEARCH
- Nanotechnology in Cancer Therapy: Targeting the Inhibition of Key DNA Repair Pathways
- (2010) K. Aziz et al. CURRENT MOLECULAR MEDICINE
- Heat shock proteins (chaperones) in fish and shellfish and their potential role in relation to fish health: a review
- (2010) R J Roberts et al. JOURNAL OF FISH DISEASES
- Novel Small-Molecule Inhibitor of Apurinic/Apyrimidinic Endonuclease 1 Blocks Proliferation and Reduces Viability of Glioblastoma Cells
- (2010) A. Bapat et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Beyond PARP Inhibitors: Agents in Pipelines Target DNA Repair Mechanisms
- (2010) A. Maxmen JNCI-Journal of the National Cancer Institute
- Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
- (2010) Svetlana Usanova et al. Molecular Cancer
- A Review of Trabectedin (ET-743): A Unique Mechanism of Action
- (2010) Maurizio D'Incalci et al. MOLECULAR CANCER THERAPEUTICS
- REPAIRtoire--a database of DNA repair pathways
- (2010) K. Milanowska et al. NUCLEIC ACIDS RESEARCH
- Redox Regulation of DNA Repair: Implications for Human Health and Cancer Therapeutic Development
- (2009) Meihua Luo et al. ANTIOXIDANTS & REDOX SIGNALING
- Identification of a Small Molecule Inhibitor of the Human DNA Repair Enzyme Polynucleotide Kinase/Phosphatase
- (2009) G. K. Freschauf et al. CANCER RESEARCH
- DNA Repair in Mammalian Cells
- (2009) A. B. Robertson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Coordination of DNA Mismatch Repair and Base Excision Repair Processing of Chemotherapy and Radiation Damage for Targeting Resistant Cancers
- (2009) T. J. Kinsella CLINICAL CANCER RESEARCH
- Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation
- (2009) April M Reed et al. Future Oncology
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
- (2009) S. E. Golding et al. MOLECULAR CANCER THERAPEUTICS
- Synthetic lethality: a framework for the development of wiser cancer therapeutics
- (2009) William G Kaelin Genome Medicine
- Going Ape as an Approach to Cancer Therapeutics
- (2008) Aditi Bapat et al. ANTIOXIDANTS & REDOX SIGNALING
- The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme
- (2008) Gianluca Tell et al. ANTIOXIDANTS & REDOX SIGNALING
- Inhibitors of DNA polymerase β: Activity and mechanism
- (2008) Zhijie Gao et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Implications of Apurinic/Apyrimidinic Endonuclease in Reactive Oxygen Signaling Response after Cisplatin Treatment of Dorsal Root Ganglion Neurons
- (2008) Y. Jiang et al. CANCER RESEARCH
- Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair
- (2008) X. Chen et al. CANCER RESEARCH
- The endless tale of non-homologous end-joining
- (2008) Eric Weterings et al. CELL RESEARCH
- Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
- (2008) Sarah C Shuck et al. CELL RESEARCH
- The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: Therapeutic implications in tumor angiogenesis
- (2008) Gang-Ming Zou et al. JOURNAL OF CELLULAR PHYSIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation