Cancer genome sequencing and potential application in oncology

Benefits and Harms of Prostate-Specific Antigen Screening for Prostate Cancer: An Evidence Update for the U.S. Preventive Services Task Force

(2013) Kenneth Lin et al.   ANNALS OF INTERNAL MEDICINE

Multigene assays and isolated tumor cells for early breast cancer treatment: time for bionetworks

(2010) Dimitrios H Roukos et al.   Expert Review of Anticancer Therapy

From tumor size andHER2status to systems oncology for very early breast cancer treatment

(2010) Dimitrios H Roukos et al.   Expert Review of Anticancer Therapy

Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management?

(2010) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Genotype–phenotype map and molecular networks: a promising solution in overcoming colorectal cancer resistance to targeted treatment

(2010) Dimitrios H Roukos et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Parliament needs members who are scientifically literate

(2010) Stéphane Goldstein   NATURE

The human genome at ten

(2010)   NATURE

Human genome at ten: Life is complicated

(2010) Erika Check Hayden   NATURE

Big science: The cancer genome challenge

(2010) Heidi Ledford   NATURE

Multiple personal genomes await

(2010) J. Craig Venter   NATURE

Has the revolution arrived?

(2010) Francis Collins   NATURE

Performance of Common Genetic Variants in Breast-Cancer Risk Models

(2010) Sholom Wacholder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Individual genomes and personalized medicine: life diversity and complexity

(2010) Christos Katsios et al.   Personalized Medicine

Systems medicine: a real approach for future personalized oncology?

(2010) Dimitrios H Roukos   PHARMACOGENOMICS

Complete genome sequencing and network modeling to overcome trastuzumab resistance

(2010) Dimitrios H Roukos   PHARMACOGENOMICS

Genetics and Personal Genomics for Personalized Breast Cancer Surgery: Progress and Challenges in Research and Clinical Practice

(2009) Dimosthenis Ziogas et al.   ANNALS OF SURGICAL ONCOLOGY

Targeting Gastric Cancer with Trastuzumab: New Clinical Practice and Innovative Developments to Overcome Resistance

(2009) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

Current concerns and challenges regarding tailored anti-angiogenic therapy in cancer

(2009) Dimitrios H Roukos et al.   Expert Review of Anticancer Therapy

Novel clinico–genome network modeling for revolutionizing genotype–phenotype-based personalized cancer care

(2009) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

New, but Not Improved? Incorporating Comparative-Effectiveness Information into FDA Labeling

(2009) Randall S. Stafford et al.   NEW ENGLAND JOURNAL OF MEDICINE

Isolated Tumor Cells in Breast Cancer

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Does Comparative-Effectiveness Research Threaten Personalized Medicine?

(2009) Alan M. Garber et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

(2009) Eric Van Cutsem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association studies in cancer

(2008) D. F. Easton et al.   HUMAN MOLECULAR GENETICS

Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer

(2008) Helena Linardou et al.   LANCET ONCOLOGY

Reverse engineering the genotype–phenotype map with natural genetic variation

(2008) Matthew V. Rockman   NATURE

Progress and challenges in genome-wide association studies in humans

(2008) Peter Donnelly   NATURE

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

(2008) Sekar Kathiresan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trastuzumab in the Adjuvant Treatment of Early-Stage Breast Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2008) I. J. Dahabreh et al.   ONCOLOGIST