Individual genomes and personalized medicine: life diversity and complexity

From tumor size andHER2status to systems oncology for very early breast cancer treatment

(2010) Dimitrios H Roukos et al.   Expert Review of Anticancer Therapy

Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management?

(2010) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Parliament needs members who are scientifically literate

(2010) Stéphane Goldstein   NATURE

Human genome at ten: The sequence explosion

(2010)   NATURE

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

(2010) Yiping He et al.   NATURE

Point: Hypotheses first

(2010) Robert Weinberg   NATURE

The human genome at ten

(2010)   NATURE

Human genome at ten: Life is complicated

(2010) Erika Check Hayden   NATURE

Multiple personal genomes await

(2010) J. Craig Venter   NATURE

Has the revolution arrived?

(2010) Francis Collins   NATURE

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Performance of Common Genetic Variants in Breast-Cancer Risk Models

(2010) Sholom Wacholder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systems medicine: a real approach for future personalized oncology?

(2010) Dimitrios H Roukos   PHARMACOGENOMICS

Genetics and Personal Genomics for Personalized Breast Cancer Surgery: Progress and Challenges in Research and Clinical Practice

(2009) Dimosthenis Ziogas et al.   ANNALS OF SURGICAL ONCOLOGY

Targeting Gastric Cancer with Trastuzumab: New Clinical Practice and Innovative Developments to Overcome Resistance

(2009) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

Personalized cancer diagnostics and therapeutics

(2009) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Novel clinico–genome network modeling for revolutionizing genotype–phenotype-based personalized cancer care

(2009) Dimitrios H Roukos   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Twenty-One–Gene Assay: Challenges and Promises in Translating Personal Genomics and Whole-Genome Scans Into Personalized Treatment of Breast Cancer

(2009) Dimitrios H. Roukos   JOURNAL OF CLINICAL ONCOLOGY

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Radiation Therapy for Breast Cancer

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Personal Genomics and Genome-Wide Association Studies: Novel Discoveries but Limitations for Practical Personalized Medicine

(2008) Dimitrios H. Roukos   ANNALS OF SURGICAL ONCOLOGY

Reverse engineering the genotype–phenotype map with natural genetic variation

(2008) Matthew V. Rockman   NATURE

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

(2008) Sekar Kathiresan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE