Isoform-specific inhibitors of ACATs: recent advances and promising developments

Pyripyropene A, an Acyl–Coenzyme A:Cholesterol Acyltransferase 2–Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia

(2011) Taichi Ohshiro et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Weighing the Benefits of High-Dose Simvastatin against the Risk of Myopathy

(2011) Amy Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

A selective ACAT-1 inhibitor, K-604, stimulates collagen production in cultured smooth muscle cells and alters plaque phenotype in apolipoprotein E-knockout mice

(2010) Yasunobu Yoshinaka et al.   ATHEROSCLEROSIS

Purification of Recombinant Acyl-Coenzyme A:Cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy

(2010) Catherine C. Y. Chang et al.   BIOCHEMISTRY

ACAT inhibition and amyloid beta reduction

(2010) Raja Bhattacharyya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Therapies Targeting Exogenous Cholesterol Uptake: New Insights and Controversies

(2010) Michael H. Davidson   Current Atherosclerosis Reports

Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1

(2010) Hiroyuki Yamazaki et al.   JOURNAL OF ANTIBIOTICS

Inhibition of Acyl-Coenzyme A:Cholesterol Acyltransferase 2 (ACAT2) Prevents Dietary Cholesterol-associated Steatosis by Enhancing Hepatic Triglyceride Mobilization

(2010) Heather M. Alger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

(2010)   LANCET

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

(2010) E. Y. Bryleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acyl-coenzyme A:cholesterol acyltransferases

(2009) Ta-Yuan Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Natural Products Beauveriolide I and III: a New Class of β-Amyloid-Lowering Compounds

(2009) Daniel P. Witter et al.   CHEMBIOCHEM

The Selectivity of Beauveriolide Derivatives in Inhibition toward the Two Isozymes of Acyl-CoA : cholesterol Acyltransferase

(2009) Taichi Ohshiro et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

ACAT Inhibition and Progression of Carotid Atherosclerosis in Patients With Familial Hypercholesterolemia

(2009) Marijn C. Meuwese et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Carotid Atherosclerosis Progression and ACAT Inhibition

(2009) Paolo Parini   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Selectivity of Pyripyropene Derivatives in Inhibition toward Acyl-CoA:cholesterol Acyltransferase 2 Isozyme

(2009) Taichi Ohshiro et al.   JOURNAL OF ANTIBIOTICS

Selective Inhibition of Acyl-CoA:cholesterol Acyltransferase 2 Isozyme by Flavasperone and Sterigmatocystin from Aspergillus Species

(2009) Kent Sakai et al.   JOURNAL OF ANTIBIOTICS

Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation

(2009) Hiroyuki Yamazaki et al.   JOURNAL OF ANTIBIOTICS

Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1: I. Taxonomy, fermentation, isolation and biological properties

(2009) Hiroyuki Yamazaki et al.   JOURNAL OF ANTIBIOTICS

Synthesis and biological evaluation of a focused library of beauveriolides

(2008) Kenichiro Nagai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of putative active site residues of ACAT enzymes

(2008) Akash Das et al.   JOURNAL OF LIPID RESEARCH

LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat

(2008) Chiara Degirolamo et al.   JOURNAL OF LIPID RESEARCH