ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

Acyl-coenzyme A:cholesterol acyltransferases

(2009) Ta-Yuan Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

(2009) David W. Russell et al.   Annual Review of Biochemistry

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

(2009) Henri J. Huttunen et al.   FASEB JOURNAL

Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis

(2009) Andrew J. Brown et al.   MOLECULAR ASPECTS OF MEDICINE

Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan

(2009) R. W. Halford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

(2009) B. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Studies of the Transmembrane C-Terminal Domain of the Amyloid Precursor Protein (APP): Does APP Function as a Cholesterol Sensor?†‡

(2008) Andrew J. Beel et al.   BIOCHEMISTRY

Proteins and cholesterol-rich domains

(2008) Richard M. Epand   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Relevance of Transgenic Mouse Models to Human Alzheimer Disease

(2008) Debbi A. Morrissette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Are side-chain oxidized oxysterols regulators also in vivo?

(2008) Ingemar Björkhem   JOURNAL OF LIPID RESEARCH

The Effect of 24S-Hydroxycholesterol on Cholesterol Homeostasis in Neurons: Quantitative Changes to the Cortical Neuron Proteome

(2008) Yuqin Wang et al.   JOURNAL OF PROTEOME RESEARCH

ACAT as a Drug Target for Alzheimer’s Disease

(2008) Henri J. Huttunen et al.   Neurodegenerative Diseases

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

(2007) Nan Wang et al.   FASEB JOURNAL