Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

(2014) M Chiu et al.   BRITISH JOURNAL OF CANCER

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling

(2014) Peng Yang et al.   CELLULAR SIGNALLING

The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation

(2014) Alfredo Csibi et al.   CURRENT BIOLOGY

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

(2014) Matjaz Rokavec et al.   JOURNAL OF CLINICAL INVESTIGATION

Incidence and survival in late liver metastases of colorectal cancer

(2014) Pierre Landreau et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Association of cancer metabolism-related proteins with oral carcinogenesis – indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?

(2014) Martin Grimm et al.   Journal of Translational Medicine

OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

(2014) Yi Zhou et al.   Molecular Cancer

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

(2014) L. Yang et al.   Molecular Systems Biology

Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer

(2014) Fotios Loupakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition

(2014) A. Hamabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut

(2014) Maia Chanrion et al.   Nature Communications

Cause of Death from Liver Metastases in Colorectal Cancer

(2013) Thomas S. Helling et al.   ANNALS OF SURGICAL ONCOLOGY

Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy

(2013) Séverine Lorin et al.   Autophagy

Paired related homoeobox 1, a new EMT inducer, is involved in metastasis and poor prognosis in colorectal cancer

(2013) Y Takahashi et al.   BRITISH JOURNAL OF CANCER

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

(2013) Seung Min Jeong et al.   CANCER CELL

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

(2013) Luika A. Timmerman et al.   CANCER CELL

Gankyrin Activates IL-8 to Promote Hepatic Metastasis of Colorectal Cancer

(2013) Z. Bai et al.   CANCER RESEARCH

Cancer as a metabolic disease: implications for novel therapeutics

(2013) T. N. Seyfried et al.   CARCINOGENESIS

Oral administration of naturally occurring chitosan-based nanoformulated green tea polyphenol EGCG effectively inhibits prostate cancer cell growth in a xenograft model

(2013) N. Khan et al.   CARCINOGENESIS

The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4

(2013) Alfred Csibi et al.   CELL

Epithelial-to-mesenchymal transition and stem cells in endometrial cancer

(2013) Cristina Mirantes et al.   HUMAN PATHOLOGY

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility

(2013) C Zhou et al.   ONCOGENE

Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration

(2012) Christine A. Caneba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Epigenetic regulation of miR-124 by Hepatitis C Virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3

(2012) Bing Zeng et al.   FEBS LETTERS

Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer

(2012) R. Shukla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

(2012) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells

(2011) N. Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition

(2011) Hua Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

(2010) W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of Long-term Survival After Hepatic Resection for Metastatic Colorectal Cancer

(2009) Myrddin Rees et al.   ANNALS OF SURGERY

Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling

(2009) C. Yang et al.   CANCER RESEARCH

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

Urgent Need for a New Staging System in Advanced Colorectal Cancer

(2008) Graeme J. Poston et al.   JOURNAL OF CLINICAL ONCOLOGY