Article
Plant Sciences
Bruna Orsi, Ivan Sestari, Ana Paula Preczenhak, Allan Patrick de Abreu Vieira, Magda Andreia Tessmer, Mayara Adja da Silva Souza, Neuza Mariko Aymoto Hassimotto, Ricardo Alfredo Kluge
Summary: Carotenoids in tomato fruit have a potential role in defense against the necrotrophic fungus Botrytis cinerea. Fruit with a higher diversity of carotenoid isomers showed lower susceptibility to the pathogen and had improved antioxidant capacity.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Plant Sciences
Hee Ju Yoo, Mi-Young Chung, Hyun-Ah Lee, Soo-Bin Lee, Silvana Grandillo, James J. Giovannoni, Je Min Lee
Summary: Carotenoids and apocarotenoids play important roles in pigmentation and flavor production in plants, contributing to their aesthetic and nutritional value. This study identifies carotenoid cleavage dioxygenase 4 (CCD4) as the factor responsible for controlling the dark orange color of tomato fruit. Overexpression of CCD4b leads to changes in carotenoid and apocarotenoid levels in ripe fruit, indicating feedback regulation in the pathway. The findings provide valuable insights into improving the quality and understanding the regulatory mechanisms of carotenoid and apocarotenoid biogenesis in tomato.
Article
Biochemistry & Molecular Biology
Franco Fusi, Giovanni Romano, Giovanna Speranza, Giovanni Agati
Summary: Studying the cis-trans isomerization process in crocin (CR), a water-soluble carotenoid extracted from saffron, is crucial for understanding its physiological role and potential as antioxidants. The isomerization of methanol- and water-dissolved CR was induced by light or singlet oxygen, and monitored using HPLC and spectrophotometric methods. The results supported a comprehensive model where cis-trans isomerization occurs from the triplet state, with a higher efficiency from cis to trans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Rima Urbstaite, Lina Raudone, Valdimaras Janulis
Summary: In this study, the qualitative and quantitative composition of anthocyanins and anthocyanidins in different cultivars and genetic clones of American cranberries grown in Lithuanian climatic conditions were analyzed. The study found that different cranberry cultivars contained various anthocyanin compounds, and compared the cultivars using hierarchical cluster analysis and principal component analysis. Additionally, the antioxidant effect of cranberry fruit sample extracts was evaluated.
Article
Food Science & Technology
Silvia Tagliamonte, Raffaele Romano, Manuela Flavia Chiacchio, Alessandra Aiello, Lucia De Luca, Vincenzo Salzano, Paola Vitaglione
Summary: This study aimed to reutilize tomato pomace, a by-product of the tomato-processing industry, in the development of tomato sauce and assess its nutritional content and bioaccessibility. The innovative tomato sauce products showed higher levels of carotenoids, α-tocopherol, and total antioxidant capacity (TAC) compared to traditional sauce. Bioaccessibility of carotenoids and α-tocopherol varied among the different tomato sauce formulations, while total polyphenols content was higher in the sauce with 100% tomato pomace.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Carolina Rivera, Hector A. Bacilio-Beltran, Ana M. Puebla-Perez, Irma I. Rangel-Salas, Jose G. Alvarado-Rodriguez, Roberto Flores-Moreno, Gilberto Velazquez-Juarez, A. Aaron Peregrina-Lucano, Elvia Becerra-Martinez, Jaime Valdez-Ruvalcaba, Jose E. Rubio, Sara A. Cortes-Llamas
Summary: The synthesis of cis and trans isomers of platinum complexes with a symmetric N-heterocyclic carbene ligand has been reported. These complexes were obtained from a masked N-heterocyclic carbene precursor. Their cytotoxicity, oxidative nature, and antibacterial behavior were investigated, and the cis-[Pt((NHC)-N-Me)(2)Cl-2] complex exhibited the highest cytotoxic effect in the HeLa cervical cancer cell line.
NEW JOURNAL OF CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Kandi Sridhar, Baskaran Stephen Inbaraj, Bing-Huei Chen
Summary: This review summarizes the advances in preparation, characterization, biocompatibility and application of nanocarotenoids reported in research/review papers published in peer-reviewed journals over the last five years. Nanocarotenoids can be prepared from carotenoid extracts and standards using various techniques, yielding different nanostructures including nanoemulsions, nanoliposomes, polymeric/biopolymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid nanoparticles, supercritical fluid-based nanoparticles and metal/metal oxide nanoparticles.
Article
Chemistry, Physical
Dariusz M. Niedzwiedzki
Summary: Application of femtosecond time-resolved transient absorption spectroscopy revealed new spectroscopic features for the cis isomers of lutein and spirilloxanthin. A distinctive transient absorption band was observed for the central-cis spirilloxanthin, absent in the all-trans isomers. This band could be attributed to a transient cis-peak and could be useful for studying the dynamics of carotenoid isomers.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Physical
Dariusz M. Niedzwiedzki
Summary: The application of femtosecond time-resolved transient absorption spectroscopy on two carotenoids, lutein and spirilloxanthin, revealed new spectroscopic features for the cis isomers. A distinct additional transient absorption band was observed in the central-cis spirilloxanthin, absent in the all trans isomers, suggesting it could be assigned to transient cis-peak. This new spectral band could be useful for studying carotenoid isomers and their distorted forms.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Plant Sciences
Lingrong Wen, Ting Zhou, Yueming Jiang, Liang Gong, Bao Yang
Summary: The study identified four prenylated phenolics in mulberry leaf, with moracin N demonstrating good neuroprotective activity by inhibiting oxidative stress through multiple mechanisms and enhancing antioxidant defense and regulation of iron death.
Article
Plant Sciences
G. Efremov, E. A. Dzhos, A. A. Ashikhmin, E. Z. Kochieva, A. Shchennikova
Summary: The tomato is a convenient model for studying carotenoid metabolism, and research on different tomato cultivars revealed a correlation between fruit color, carotenoid content/composition, and chlorophyll presence. The CRTISO gene shows highest expression during fruit color change and biological ripeness, but this expression level does not strongly correlate with total carotenoid levels.
RUSSIAN JOURNAL OF PLANT PHYSIOLOGY
(2022)
Article
Chemistry, Applied
Dimas Rahadian Aji Muhammad, Emmy Tuenter, Graha Darma Patria, Kenn Foubert, Luc Pieters, Koen Dewettinck
Summary: The study showed that cinnamon extract has the potential to enhance the health-promoting properties of white chocolate, increasing its antioxidant activity. Encapsulated cinnamon extract significantly increased the phenolic content of white chocolate.
Article
Food Science & Technology
Nicola Pinna, Federica Ianni, Roberto Selvaggini, Stefania Urbani, Michela Codini, Luca Grispoldi, Beniamino Terzo Cenci-Goga, Lina Cossignani, Francesca Blasi
Summary: Pumpkin is not only a food rich in nutrients, but also contains bioactive compounds that have a wide range of health-promoting effects. Peel and filaments of pumpkin varieties were found to be a good source of beta-carotene and other carotenoids, as well as having antioxidant activity. These pumpkin byproducts could be valuable in the development of novel functional food products.
Article
Microbiology
Nidhi Soni, Pinakin Dhandhukia, Janki N. Thakker
Summary: Marine bacteria have the potential to be a natural source of carotenoids. Bacillus infantis, a marine bacterium capable of synthesizing carotenoids, was isolated and used to produce an orange pigment. The orange pigment was characterized as a carotenoid group of pigment through various analytical methods, and showed antimicrobial and antioxidant activities. These findings suggest that the carotenoids from these strains have promising biotechnological applications.
ARCHIVES OF MICROBIOLOGY
(2023)
Article
Nutrition & Dietetics
Yan He, Yu Wang, Mengzhuo Zhang, Guangsen Liu, Cong Tian, Xiangbin Xu, Yonggui Pan, Xuequn Shi, Zhengke Zhang, Lanhuan Meng
Summary: This study found that the transcription factor SlBEL11 plays a role in regulating carotenoid accumulation in tomato fruit. Through gene silencing and RNA interference experiments, it was found that the transcription level of the SlLCY-b2 gene increased significantly, leading to enhanced carotenoid biosynthesis. Electrophoretic mobility shift assay confirmed the binding of SlBEL11 protein to the promoter of SlLCY-b2 gene, and the dual-luciferase reporter assay showed its transcriptional repression activity.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Qi-rui Hu, Peng-wei Lai, Fang Chen, Yan-fang Yu, Bing Zhang, Hongyan Li, Rong Liu, Yawei Fan, Ze-yuan Deng
Summary: This study investigated the potential of using spray drying to process whole mulberry leaves into nutraceutical foods rich in phenolic compounds. The results showed that the spray-dried product 6, with a high ratio of whey protein isolate to mulberry leaves solid, had the best physical properties, highest total phenolic compounds level, and highest antioxidant capacity. The in vitro digestion also showed that the bioaccessibility of phenolic compounds in product 6 was significantly higher than that in fresh mulberry leaves.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Food Science & Technology
Yao Pan, Hongyan Li, Xuan Chen, Yawei Fan, Bing Zhang, Rong Liu, Ze-yuan Deng
Summary: This study investigated the antioxidant interactions between hydrophilic and lipophilic phytochemicals, showing that the ratios and concentrations of these compounds can influence the outcomes of antioxidant synergism or antagonism. Proper consideration of concentrations and ratios of these compounds is recommended for diet and formulation of functional foods.
Article
Biochemistry & Molecular Biology
Lihua Xiao, Hua Xiong, Zeyuan Deng, Xin Peng, Kejun Cheng, Hua Zhang, Li Jiang, Yong Sun
Summary: Tetrastigma hemsleyanum leaf extracts can improve nonalcoholic fatty liver disease (NAFLD) by regulating the gut-liver axis, reducing oxidative stress, lipid accumulation, and inflammation.
Review
Biochemistry & Molecular Biology
Abdul Mueed, Zeyuan Deng, Sameh A. Korma, Sahar Shibli, Muhammad Jahangir
Summary: Lignans found in flaxseed have shown promising anticancer activity by inducing apoptosis, inhibiting cell proliferation, and impeding metastasis and angiogenesis. They can be metabolized by gut microbes into metabolites that can be easily absorbed. This review summarizes the bioavailability, mechanisms, safety, and future research scope of flaxseed lignans as chemotherapeutics/chemopreventive agents for cancer management and prevention.
Review
Nutrition & Dietetics
Qinghua Xi, Weixin Liu, Tianyuan Zeng, Xuan Chen, Ting Luo, Zeyuan Deng
Summary: The aim of this meta-analysis was to review the relationship between lactation diet and the composition of mature breast milk. 27 cross-sectional studies were included, involving 4355 lactating women. The results showed that fat content in mature milk increased with fat intake, while protein and lactose contents did not increase with their intakes. The rational dietary pattern was recommended, and high-fat and high-protein dietary patterns should be avoided during lactation.
Article
Food Science & Technology
Yuchen Ma, Guangyi Wang, Zeyuan Deng, Bing Zhang, Hongyan Li
Summary: This research investigated the effects of endogenous anti-oxidative components of ten common edible vegetable oils on oxidation. The major components identified were tocopherols, sterols, polyphenols, and squalene, with alpha-tocopherol, beta-sitosterol, and polyphenols showing good anti-oxidative activity. The oxidative stability of edible vegetable oils was influenced by factors such as fatty acid composition and temperature.
Article
Agriculture, Multidisciplinary
Nan Li, Ruiyan Wang, Wenwen Li, Qian Du, Zeyuan Deng, Yawei Fan, Liufeng Zheng
Summary: This study revealed the anti-inflammatory properties of vitexin in a mouse model of colitis and its ability to enhance the expression of barrier-associated proteins. Through thermal proteome profiling and molecular docking, OLA1 was identified as a potential protein target for vitexin. Further experiments demonstrated that OLA1 can increase Nrf2 protein expression, thereby mediating the anti-inflammatory effects of vitexin.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Nan Li, Ruiyan Wang, Zeyuan Deng, Jianqun Zhou, Wenwen Li, Qian Du, Liufeng Zheng
Summary: Sucrose is shown to be a stable metal-ion chelating agent that can enhance the absorption of metal ions. This study explores the structure of the zinc-sucrose complex and its ability to promote zinc absorption in cells and mice. The complex increases zinc uptake and transport, upregulates genes and proteins involved in zinc absorption, and interacts with zinc transport proteins. These findings offer valuable insights into the mechanisms of zinc absorption and suggest potential applications in treating zinc deficiency.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Agriculture, Multidisciplinary
Liuying Zhu, Hongyan Li, Ting Luo, Zeyuan Deng, Jing Li, Liufeng Zheng, Bing Zhang
Summary: Human milk oligosaccharides (HMOs), a unique group of oligosaccharides found in human milk, have gained great interest due to their positive effects on infant health. However, the clinical application of HMOs is challenging due to their specificity to human milk and the associated difficulties and high costs. This article compares oligosaccharides in human and other mammalian milk, summarizes the synthetic strategies for accessing HMOs, reviews the potential use and molecular mechanisms of HMOs in different diseases, and discusses the current challenges and prospects of HMOs in basic research and application.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Yangzheng He, Yong Sun, Jing Li, Xiaoyu Peng, Wei Li, Yu Gao, Jiaqi Wang, Xinggang Ni, Lina Pan, Zeyuan Deng
Summary: Although formula-fed infants are more prone to obesity than breastfed ones, this study found that administering human milk fat substitutes (HMFS) did not affect body weight in rats, but significantly decreased body fat content. The study also revealed the potential mechanism by which HMFS affects body fat buildup and promotes lipid metabolism in the liver. These findings underscore the nutritional benefits of HMFS for infants.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Ting Xiao, Junpeng Zeng, Caidong Zhao, Yanmei Hou, Tong Wu, Zeyuan Deng, Liufeng Zheng
Summary: This study utilized an in vitro infant digestion model to investigate protein digestion characteristics in human and various mammalian milk. The differences in milk digestion were mainly observed in the infant gastric phase, with varying degrees of protein digestion. Proteins in human milk remained partially intact after digestion, while these proteins in animal milk were completely degraded. The peptide spectra of human, mare, and camel milk were highly similar, with the predominant formation of low-intensity small peptides. Sheep milk exhibited the most similar protein digestion behaviors to human milk following infant gastric digestion.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Teng Wei, Dengfeng Tan, Shengyue Zhong, Hong Zhang, Zeyuan Deng, Jing Li
Summary: The most abundant triacylglycerol (TAG) in Chinese human milk is 1-oleate-2-palmitate-3-linoleate (OPL), which is different from other countries where 1,3-oleate-2-palmitate (OPO) is the most abundant TAG. This study investigated the effects of an OPL-supplemented diet on mice's nutritional outcomes and found that high OPL (HOPL) diet improved lipid metabolism and gut bacteria, reducing the level of pro-inflammatory cytokines. Furthermore, the study revealed a relationship between gut bacteria, lipidome profile, and nutritional outcomes.
Article
Agriculture, Multidisciplinary
Teng Wei, Dengfeng Tan, Shengyue Zhong, Hong Zhang, Zeyuan Deng, Jing Li
Summary: This study investigated the differences in absorption and metabolism between OPO and OPL and found that OPL was associated with higher blood lipid and cholesterol concentrations. However, mice fed with OPO and OPL showed lower body weight and lipid levels in the liver.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Yangzheng He, Yong Sun, Jing Li, Xiaoyu Peng, Wei Li, Yu Gao, Jiaqi Wang, Xinggang Ni, Lina Pan, Zeyuan Deng
Summary: This study aimed to investigate the impact of human milk fat substitutes (HMFS) on lipid metabolism in first-weaned Sprague Dawley rats. The findings showed that HMFS administration did not affect body weight but significantly decreased body fat content. Lipidome analysis revealed changes in glycerophospholipid levels in the liver of HMFS-fed rats. Furthermore, HMFS administration promoted lipid metabolism in the rat liver at both the gene and protein levels.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
