Article
Plant Sciences
Rodrigo Cortes-Antiquera, Marisol Pizarro, Rodrigo A. Contreras, Hans Kohler, Gustavo E. Zuniga
Summary: Antarctic hair grass (Deschampsia antarctica) is a successful colonizing species on a cold continent. With the increasing frequency of heat waves in Antarctica due to climate change, populations of D. antarctica are responding positively, showing increased numbers and sizes. When subjected to heat shock treatments, D. antarctica plants are capable of tolerating higher temperatures without visible damage, thanks to efficient enzymatic and non-enzymatic antioxidant systems maintaining redox balance.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Ross J. Taylor, Michael B. Geeson, Toby Journeaux, Goncalo J. L. Bernardes
Summary: This article focuses on the progress of chemical and enzymatic approaches in generating protein-protein conjugates through post-translational processes. Various methods and their applications are discussed, highlighting the successes and challenges of these approaches, as well as future directions for further development.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Review
Chemistry, Medicinal
Fernanda Isabel Della Via, Marisa Claudia Alvarez, Rosanna Tarkany Basting, Sara Teresinha Olalla Saad
Summary: Green tea catechins, particularly EGCG, have been found to induce apoptosis, modulate epigenetic alterations, and promote differentiation in leukemia cells. Understanding these multifaceted mechanisms and the outcomes of clinical trials is crucial for exploring the therapeutic potential of green tea catechins in leukemia treatment and developing innovative strategies. Further research is needed to fully comprehend the comprehensive actions of green tea catechins in improving leukemia patient outcomes.
Article
Engineering, Chemical
Pedro Velho, Leonor R. Barroca, Eugenia A. Macedo
Summary: Fruits and vegetables are commonly used as feedstocks for natural antioxidants, but their use raises moral and environmental concerns. This study explores the feasibility of using antioxidant-rich biowaste as a raw material for dietary supplements, contributing to a more circular economy and sustainable therapeutics.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Polymer Science
Francesca Perin, Carlos Mota, Ines Mancini, Antonella Motta, Devid Maniglio
Summary: This research demonstrates the photo-triggering of horseradish peroxidase (HRP) dityrosine crosslinking by introducing riboflavin as a photosensitizer and exposing the polymer to light radiation. The method proved to be superior to UV crosslinking and offered the possibility of precise triggering of the reaction with UV light. The photo-enzymatic crosslinking was applied to bioprinting, showing its potential in biofabrication techniques.
Article
Integrative & Complementary Medicine
Wang You-Xu, Cao Ning, Guan Hui-Da, Cheng Xue-Mei, Wang Chang-Hong
Summary: This study found that heme peroxidases catalyze the oxidative reaction of harmaline and revealed the metabolic pathway of harmaline in blood. The findings are of great significance for understanding the metabolism of carboline compounds and pharmacokinetic studies.
CHINESE JOURNAL OF NATURAL MEDICINES
(2022)
Article
Polymer Science
Domenico Sagnelli, Ambra Vestri, Silvio Curia, Vincenzo Taresco, Gabriella Santagata, Mats K. G. Johansson, Steven M. Howdle
Summary: There is significant potential for industrial use of renewables in producing a variety of materials, with particular focus on utilizing the suberin extracted from the bark of birch trees. By leveraging biocatalysts and supercritical carbon dioxide for low temperature polycondensation, sustainable polyesters based on cis-9,10-epoxy-18-hydroxyoctadecanoic acid can be created for bio-renewable coatings.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Malgorzata Latos-Brozio, Anna Masek, Malgorzata Piotrowska
Summary: This study successfully achieved enzymatic polymerization of naringenin and investigated the properties of poly(naringenin). It was found that the polymeric forms of naringenin exhibited improved thermal stability, antioxidant activity, and antimicrobial properties compared to the basic flavonoid. In particular, poly(naringenin)-laccase showed better scavenging activity for ABTS(+center dot) radicals and antimicrobial activity against E. coli.
Article
Food Science & Technology
Zhuolin Song, Lin Feng, Yuankui Leng, Mingzhu Huang, Hao Fang, Weipeng Tong, Xuelan Chen, Yonghua Xiong
Summary: This study significantly increased the sensitivity of immunoassay for OTA detection using a cascade-amplifying system, introducing a biotinylated M13 bacteriophage and polyHRP structure to construct a highly sensitive OTA detection method. The proposed method displayed acceptable accuracy and slight cross-reaction in real corn samples, showing potential for ultra-trace OTA determination.
Article
Biochemistry & Molecular Biology
Rie Mukai, Takashi Fukuda, Asami Ohnishi, Takeshi Nikawa, Mutsuki Furusawa, Junji Terao
Summary: The study evaluated the food matrix effects of chocolate on the absorption of green tea catechins in five healthy women. It was found that the plasma profiles of ECg were significantly affected by the chocolate matrix, with ECg persisting in the plasma for a longer period compared to EGCg.
Article
Chemistry, Multidisciplinary
Fabian B. H. Rehm, Tristan J. Tyler, Kuok Yap, Simon J. de Veer, David J. Craik, Thomas Durek
Summary: The study introduces a peptide/protein labeling strategy using an engineered transpeptidase to irreversibly incorporate diverse amines at a C-terminal asparagine, demonstrating its utility in preparing a protein-drug conjugate, generating a genetically inaccessible protein fusion, and site-specifically labeling both termini of a single protein in sequential steps.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Engineering, Electrical & Electronic
Debangana Das, Shreya Nag, Shubham De, Ajanto Kumar Hazarika, Santanu Sabhapondit, Bipan Tudu, Rajib Bandyopadhyay, Panchanan Pramanik, Runu Banerjee Roy
Summary: The study developed a cost-effective and reproducible electrode using MIP technology for selective determination and quantitative prediction of epicatechin in green tea. The electrode showed low detection limit, wide linearity ranges, and accurate predictive ability using PLSR and PCR models.
IEEE SENSORS JOURNAL
(2021)
Article
Infectious Diseases
Karin Sasagawa, Hisanori Domon, Rina Sakagami, Satoru Hirayama, Tomoki Maekawa, Toshihito Isono, Takumi Hiyoshi, Hikaru Tamura, Fumio Takizawa, Yoichi Fukushima, Koichi Tabeta, Yutaka Terao
Summary: Polyphenols in matcha green tea can combat Streptococcus pneumoniae infections, inhibit pneumolysin production, reduce cell lysis and neutrophil death.
Article
Biophysics
Kai Yan, Ponnusamy Nandhakumar, Aman Bhatia, Nam-Sihk Lee, Young Ho Yoon, Haesik Yang
Summary: An electrochemical immunosensor based on a choline oxidase (ChOx)-HRP cascade reaction has been reported, showing superior performance compared to the commonly used glucose oxidase (GOx)-HRP cascade. The ChOx-HRP cascade allows in situ generation of H2O2 and oxidation of substrates in the presence of HRP, making it promising for highly sensitive electrochemical immunoassays. The developed ChOx-HRP cascade was successfully applied in a sandwich-type immunoassay of parathyroid hormone, with a detection limit of approximately 3 pg/mL in artificial and clinical serum samples.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Polymer Science
Frances Dawson, Touseef Kazmi, Peter J. Roth, Maciej Kopec
Summary: Degradable poly(n-butyl acrylate) networks were synthesized through RAFT polymerization, and the mechanical properties of the prepared gels were not significantly affected by the incorporation of degradable units. The degraded fragments of different topology can be repolymerized into solid networks through redox reactions.
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.