Article
Pharmacology & Pharmacy
Qingqiang Ni, Yuxuan Gao, Xiuzhen Yang, Qingmeng Zhang, Baojian Guo, Jinxiang Han, Shaoru Chen
Summary: Licorice, a traditional herbal medicine, contains important active ingredients glycyrrhizic acid (GL) and glycyrrhetinic acid (GA). Both GL and GA have pharmacological effects against tumors, inflammation, and viral infections, but they also exhibit some differences. This article comprehensively reviews the therapeutic potential of GL and GA, focusing on their pharmacological effects and working mechanisms, and proposes further development of GA derivatives.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
Ali Shahi, Hamed Vafaei Molamahmood, Naser Faraji, Mingce Long
Summary: In this study, quantitative structure-activity relationship (QSAR) models were developed to predict the second-order rate constant (k(app)) for the reaction of peracetic acid (PAA) with various organic contaminants. The models, based on different molecular descriptors, were proven to be accurate and reliable in predicting the removal efficiency of organic contaminants in wastewater treatment.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Chemistry, Applied
Lumin Yang, Lijie Jia, Xiuli Li, Ke Zhang, Xiaoxiao Wang, Yufeng He, Meng Hao, Margaret P. Rayman, Jinsong Zhang
Summary: This study compared the prooxidant activities of (-)-epigallocatechin-3-gallate (EGCG) and chlorogenic acid (CGA) in in vitro models and in mice. The results showed that EGCG exhibited powerful prooxidant effects, while CGA had none. CGA could scavenge the hydroxyl radicals generated by EGCG, leading to lower hepatotoxicity. Furthermore, low-dose EGCG and CGA synergistically activated hepatic AMPK and increased hepatic Nrf2-associated proteins without causing toxicity in mice.
Article
Engineering, Environmental
Elena Chung, Daniel P. Russo, Heather L. Ciallella, Yu-Tang Wang, Min Wu, Lauren M. Aleksunes, Hao Zhu
Summary: Traditional methodologies for assessing chemical toxicity are expensive and time-consuming, but computational modeling approaches, particularly QSAR models, provide a low-cost alternative. However, conventional QSAR models have limited training data and poor predictivity for new compounds. This study developed data-driven models for carcinogenicity and successfully identified potential new human carcinogens.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Chi-Cheung Su, Meinan He, Rachid Amine, Zonghai Chen, Zhou Yu, Tomas Rojas, Lei Cheng, Anh T. Ngo, Khalil Amine
Summary: Understanding the decay mechanism in high-voltage LIBs is crucial for establishing a stable electrolyte system. While oxidative decomposition is believed to be the main cause of capacity fade, it cannot fully explain the rapid decay in certain electrolyte systems used with high-nickel layered oxide cathode.
Article
Chemistry, Multidisciplinary
Jiaqi Shi, Tao Long, Yuxuan Zhou, Lei Wang, Cuiping Jiang, Dongguo Pan, Xin Zhu
Summary: This study investigated the optimal conditions for quinone activation of persulfate, finding that representative monoaromatics degrade fastest at pH 10.0 but excessive alkalinity can inhibit the reaction. A quantitative structure-activity relationship model revealed that the most negative atomic net charges on carbon atoms played a key role in the degradation rates, with compounds having smaller qC- values being more easily oxidized in quinone-activated systems. This finding could aid in the further exploration of effective activators in alkaline environments.
FRONTIERS IN CHEMISTRY
(2021)
Article
Food Science & Technology
Weichen Bo, Lang Chen, Dongya Qin, Sheng Geng, Jiaqi Li, Hu Mei, Bo Li, Guizhao Liang
Summary: Food-derived bioactive peptides have significant effects and are studied using data-driven computing methods. QSAR is widely used for describing structure-activity relationships but faces challenges in food science applications. Multidisciplinary research collaboration is needed to improve QSAR knowledge and discover bioactive peptides.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Spectroscopy
Marco Mellado, Rafaela Sariego-Kluge, Franco Valdes-Navarro, Cesar Gonzalez, Rodrigo Sanchez-Gonzalez, Nancy Pizarro, Joan Villena, Carlos Jara-Gutierrez, Claudio Cordova, Manuel A. Bravo, Luis F. Aguilar
Summary: In this study, 11 new fluorescent pigments were synthesized and their photophysical properties were analyzed. It was found that the chemical structure of the compounds plays a crucial role in determining their properties. The compounds were also applied as fluorescent pigments in living cell imaging, with compound 12a showing potential as an alternative.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Food Science & Technology
Qingchao Gao, Yi Li, Yahui Li, Zhiyong Zhang, Ying Liang
Summary: Phenolic acids, especially in vegetables, are important natural antioxidants. Different structures of phenolic acids exhibit varying antioxidant activities, which could benefit further research on the potential biological activities of vegetables.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Arian Kola, Ginevra Vigni, Maria Camilla Baratto, Daniela Valensin
Summary: Oxidative stress is caused by an imbalance between reactive oxygen species production and neutralization. This study investigates the antioxidant and prooxidant activities of rosmarinic acid (RA), revealing its effectiveness in copper binding abilities and ROS protection.
Article
Environmental Sciences
Xiaochen Qi, Na Liu, Zhongen Tang, Wenjuan Ou, Chuanqi Jian, Yutao Lei
Summary: In this study, a QSAR model was developed using particle swarm optimization and an extreme learning machine to understand the laws of kapp values of organic compounds during degradation by Fe (VI). The model was verified to have high reliability and predictability. Constructing the QSAR model facilitates kapp prediction for Fe (VI) in the degradation of various organic compounds, improves the understanding of the degradation mechanism, and reduces the pressure on human and material resources caused by experiments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Pharmacology & Pharmacy
Xiaoda Yang, Hongshun Qiu, Yuxiang Zhang, Peijian Zhang
Summary: The study aims to predict the inhibitory effect of amide derivatives on xanthine oxidase (XO) by building several models based on the theory of quantitative structure-activity relationship (QSAR). Linear and non-linear models were constructed using the heuristic method (HM) and XGBoost, respectively. Among the non-linear models, MIX-SVR method achieved the best result by combining different kernel functions.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Food Science & Technology
Jinwoo Yang, Junsoo Lee, Jeehye Sung
Summary: Acid treatment enhances the antioxidant activity of tartary buckwheat by converting flavonoid glycosides into their aglycones. It also shows inhibitory effects on the generation of intracellular reactive oxygen species, lipid accumulation, adipogenic factors, and inflammatory mediators. Noodles made with acid-treated tartary buckwheat flours exhibit significantly improved antioxidant activity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemical Research Methods
Yu-Liang Wang, Fan Wang, Xing-Xing Shi, Chen-Yang Jia, Feng-Xu Wu, Ge-Fei Hao, Guang-Fu Yang
Summary: Effective drug discovery is crucial for treating diseases, but is hindered by high costs and long cycles. The introduction of the QSAR method has enhanced efficiency in drug discovery, while the Cloud 3D-QSAR server provides a comprehensive solution by integrating various functions to facilitate the development of good QSAR models.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Biochemistry & Molecular Biology
Moon-Hee Choi, Seung-Hwa Yang, Da-Song Kim, Nam Doo Kim, Hyun-Jae Shin, Kechun Liu
Summary: A novel quercetin derivative, 3,7-dioleylquercetin, was synthesized and showed low cytotoxicity in skin-whitening applications. It acts as a competitive inhibitor, inhibits melanin-related gene expression, and is suitable for development of novel skin-whitening agents.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Food Science & Technology
Shengtao Bo, Sui Kiat Chang, Hong Zhu, Yueming Jiang, Bao Yang
Summary: Prenylated stilbenoids are a unique class of natural phenolic compounds with potential health benefits, including antioxidant, anti-cancer, anti-inflammatory, and anti-microbial activities. This review provides a comprehensive overview of the structure, bioactivity, potential applications, edible sources, and biosynthesis strategies of prenylated stilbenoids in the food industry. The findings regarding their use as food preservatives, nutraceuticals, and food additives are discussed, providing a full image of these compounds.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biotechnology & Applied Microbiology
Liang Gong, Ajit Kumar Passari, Chunxiao Yin, Vijay Kumar Thakur, John Newbold, William Clark, Yueming Jiang, Shanmugam Kumar, Vijai Kumar Gupta
Summary: Nowadays, the increasing production, use, and disposal of plastic products is a major environmental issue. The presence of plastic particles and other impurities in the food supply chain poses significant health risks to humans, animals, and the environment. Biodegradable plastics aim to create a more sustainable and eco-friendly world. This article discusses the critical issues that need to be addressed for the commercial viability of bioplastic production.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Article
Chemistry, Applied
Zhongsuzhi Chen, Meiying He, Yijie Zhou, Xi Chen, Hong Zhu, Bao Yang, Yueming Jiang, Hongxia Qu
Summary: Water-soluble polysaccharides were extracted from litchi pulp, with arabinogalactan identified as its main component. The dominant monosaccharide constituents were arabinose and galactose. During storage, galactose and mannose levels increased while ATP, ADP, and AMP levels decreased with pulp breakdown. The WSP depolymerized, resulting in decreased content and molecular weight but stable structure. Enzymes such as polygalacturonase, pectate lyase, 8-galactosidase, and alpha-L-arabinofuranosidase were active during different stages of storage. Except for LcPME, gene expression for LcPL, LcGAL, and LcPME was downregulated. Depolymerization was mainly caused by the rupture of branched side chains and glucuronic acid backbones, with both enzymatic and nonenzymatic factors involved.
Article
Chemistry, Applied
Qiuxia Yang, Yushan Guo, Yueming Jiang, Bao Yang
Summary: Oligosaccharides are recognized as prebiotics and their structure is closely related to bioactivity. In this study, UPLC-MS/MS was developed to identify the structure of oligosaccharides, which mainly appeared as sodium adduct in the chromatogram. The fragmentation patterns of oligosaccharides were summarized for different glycosidic linkages. The results showed that UPLC-MS/MS was effective in identifying the structure of oligosaccharides and could be applied in polysaccharide structure identification.
FOOD HYDROCOLLOIDS
(2023)
Review
Food Science & Technology
Guoxing Jing, Yuanyuan Wang, Mengping Wu, Wenjie Liu, Shaofeng Xiong, Jianna Yu, Wenshan Li, Wen Liu, Yueming Jiang
Summary: Mycotoxins, highly toxic secondary metabolites produced by fungi, pose a serious threat to food safety and human health. Photocatalytic technology has shown great promise for the degradation of mycotoxins in food due to its high efficiency and low cost, particularly for aflatoxin and deoxynivalenol. This review provides an updated overview of the progress in photocatalytic degradation of mycotoxins in food, including the characteristics of new photocatalytic materials, degradation products, and potential mechanisms and pathways. It also offers a prospect for the future application of photocatalytic technology in mycotoxin degradation.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Agriculture, Multidisciplinary
Lihong Xie, Qiuxiao Yang, Yanfei Wu, Jianbo Xiao, Hongxia Qu, Yueming Jiang, Taotao Li
Summary: The response of fungi to oxidative stress during infection on postharvest fruit is not well understood. In this study, hydrogen peroxide (H2O2) treatment was found to inhibit the growth of Fusarium proliferatum, a fungus causing crown rot of banana fruit. H2O2 exposure increased reactive oxygen species (ROS) and fumonisin B1 (FB1) production in F. proliferatum. Additionally, FB1 biosynthesis was shown to be associated with oxidative stress and contributed to fungal infection on banana fruit.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Chunxiao Yin, Hong Zhu, Yuli Lao, Yueming Jiang, Liang Gong
Summary: In this study, extracellular vesicles (EVs) were isolated and characterized from C. reticulata juice, and it was found that these EVs could significantly inhibit the mycelium growth of P. italicum on citrus fruit. Through transcriptome, sRNA, and degradome sequencing, a total of 100 miRNAs from EVs were identified and their target characterization revealed their association with host defense-related pathways. This research elucidates the molecular mechanisms of citrus exosome inhibition on P. italicum through miRNA-mediated cross-kingdom pathogen RNA interference.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Plant Sciences
Guiping Cheng, Changchun Ye, Jiajun Zhang, Hongmei Li, Yueming Jiang, Xuewu Duan
Summary: Cuticular wax protects plant tissues from water loss. The differences in surface morphology, water permeability, and chemical composition of cuticular wax were compared among leaves, calyx, and petals of two carnation cultivars at different postharvest stages. The results showed significant differences among tissues but not among cultivars or postharvest stages, suggesting a strong association between cuticular chemical composition and water barrier function.
PHYSIOLOGIA PLANTARUM
(2023)
Article
Engineering, Biomedical
Dongmei Wang, Baoshan Huang, Chenchen Zhu, Lei Wang, Jiahui Jin, Jingyang Tan, Qing Li, Shengjin Xiang, Kaihui Nan, Sen Lin
Summary: Multi-hydrophobic core nanoparticles (MHC-NPs) are synthesized using lysine oligomer-based multi-hydrophobic side chain polymers (MHCPs), which can effectively load hydrophobic molecules. These nanoparticles demonstrate high loading capacity and prolonged retention when topically administered on the eye surface.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Food Science & Technology
Wanli Zhang, Yueming Jiang, Zhengke Zhang
Summary: Fresh fruits have good flavor and high nutritional value, but they age and decay rapidly after harvest, requiring the use of green postharvest fruit preservatives. Natural organic acids are considered as promising options due to their safety and effectiveness. This review discusses the recent applications of various natural organic acids in postharvest fruit quality management, highlighting their potential biochemical mechanisms and benefits in delaying senescence, preventing chilling injury, controlling diseases, inhibiting browning, and improving overall fruit quality. Chemical modification and cotreatment strategies are also considered to enhance the efficiency of natural organic acid preservation methods.
Review
Food Science & Technology
Jiali Yang, Zhengjiao Gao, Zhiqian Yu, Yu Hou, Dingtao Tang, Huiling Yan, Fuwang Wu, Sui Kiat Chang, Yonggui Pan, Yueming Jiang, Zhengke Zhang, Bao Yang
Summary: This review summarizes the natural aurones isolated from dietary plants, a subclass of active flavonoids characterized by a scaffold of 2-benzylidene-3(2H)-benzofuranone. Their positive effects on immunomodulation, antioxidation, cancer prevention, and maintaining the health status of cardiovascular, nervous system, and liver organs are highlighted. The biosynthesis strategies of plant-derived aurones are elaborated to tackle their limited natural abundance, and the potential application of natural aurones in food coloration is discussed. This paper provides a comprehensive overview of dietary aurones, combining up-to-date information.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Yipeng Chen, Yueming Jiang, Lingrong Wen, Bao Yang
Summary: Pectin can improve the bioaccessibility of icaritin as a nanocarrier, while ultrasound can modify the pectin structure. This study investigated the effects of ultrasound-modified pectin (UMP) on the physiochemical properties of icaritin/pectin micelles (IPMs). The UMP-IPMs showed lower encapsulation efficiencies and loading capacities compared to native IPMs, but exhibited stronger anti-proliferation activities against HepG2 cells.
Article
Food Science & Technology
Qiuxia Yang, Yingjun Liu, Yushan Guo, Yueming Jiang, Lingrong Wen, Bao Yang
Summary: This paper reviews the latest reports on nutrients and phytochemicals in fig, summarizes the health benefits and side effects reported in the last decade, and discusses the impacts of postharvest processing and variety selection on fig quality. Figs are rich in bioactive phytochemicals, with prenylated phenolics being rare and having good antioxidant, anticancer, and other activities. Sugars, organic acids, coumarins, and prenylated phenolics can be used as marker chemicals for variety selection.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Yanfei Wu, Qiuxiao Yang, Lihong Xie, Chunxiao Yin, Hongxia Qu, Junxian He, Yueming Jiang, Taotao Li
Summary: Fusarium proliferatum is a pathogenic fungus that causes crown rot in banana fruit during postharvest storage. The secreted aspartic proteinase FpOPSB plays a critical role in the infection process. FpOPSB enhances the virulence of F. proliferatum by suppressing plant immunity and promoting fungal growth.
Article
Plant Sciences
Guoxiang Jiang, Zhiwei Li, Xiaochun Ding, Yijie Zhou, Hongmei Lai, Yueming Jiang, Xuewu Duan
Summary: A WUSCHEL-related homeobox transcription factor (TF), SlWOX13, regulates tomato fruit ripening via ethylene synthesis and signaling, as well as transcriptional regulation of key ripening-related TFs.
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.