Review
Food Science & Technology
Sebastien Marze
Summary: This article investigates the kinetics of lipid digestion and bioavailability and their impact on various diseases. The study finds a close link between lipid digestion kinetics and bioavailability kinetics, which can be modulated through food design or combination. The article presents different approaches, such as in vitro, modeling, in vivo, and mixed methods, to study the kinetics of both processes. It also proposes a unifying modeling scheme to better understand the role and interactions of various factors involved in lipid metabolism.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Michelle Goncalves Santana, Otniel Freitas-Silva, Lilian Regina Barros Mariutti, Anderson Junger Teodoro
Summary: International guidelines strongly recommend the frequent consumption of plant-based foods, especially fruits, due to their abundant bioactive substances. Assessing the bioaccessibility of polyphenols in tropical fruits is crucial, and various methods are used for this purpose. While standardized in vitro digestion methods exist, there is limited research on using these methods to evaluate the bioaccessibility of polyphenols in tropical fruits.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Applied
Shanmugam Sundhar, Robinson Jeya Shakila, Rajendran Shalini, Samraj Aanand, Geevaretnam Jeyasekaran, Natarajan Jayakumar
Summary: Bioaccessibility-based risk assessment can improve dietary recommendations for pesticide residue contaminated aquatic food products. The study assessed the bioaccessibility of banned organochlorine and pyrethroid pesticides in seaweeds from Gulf of Mannar using in-vitro simulation digestion. The results showed that thermal processing significantly reduces pesticide residue concentrations in seaweeds.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Review
Food Science & Technology
Talita A. Comunian, Stephan Drusch, Andre Brodkorb
Summary: This review provides an overview of the influence of structured delivery systems on in vitro digestive behavior, summarizing the main delivery systems, outlining the pros and cons of different structures, and providing examples of studies that optimized the use of these structured systems. Additionally, the review explores the use of plant-based systems in improving digestibility of encapsulated compounds and proteins/polysaccharides.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Pin Chen, Jinwei Sun, Zhiqiang Liang, Hanxue Xu, Peng Du, Aili Li, Yueyue Meng, E. Reshetnik, Libo Liu, Chun Li
Summary: Soy isoflavones show potential in regulating gut microbiota by promoting the growth of probiotics, inhibiting harmful bacteria, and affecting obesity-related bacteria. Additionally, they can significantly improve the antibacterial ability of probiotics in vitro.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Applied
Hualu Zhou, Taotao Dai, Jinning Liu, Yubing Tan, Long Bai, Orlando J. Rojas, David Julian McClements
Summary: The study found that nanochitin can retard lipid digestion while suppressing carotenoid bioaccessibility, posing potential impacts that food formulators must carefully consider.
FOOD HYDROCOLLOIDS
(2021)
Article
Multidisciplinary Sciences
Qinyi Li, Rafael P. Fernandez, Ryan Hossaini, Fernando Iglesias-Suarez, Carlos A. Cuevas, Eric C. Apel, Douglas E. Kinnison, Jean-Francois Lamarque, Alfonso Saiz-Lopez
Summary: This study demonstrates the significant impact of reactive halogens on the lifetime and radiative forcing of CH4, emphasizing the need to consider both direct and indirect effects in future projections.
NATURE COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Xiaoqiu Yang, Qi Zheng, Man He, Beibei Chen, Bin Hu
Summary: This study investigated the speciation and transformation of bromine and iodine along the Changjiang River in drinking water supply system, revealing an apparent increase of organic bromine and iodine concentrations after treatment, possibly influenced by chlorine-containing disinfectant. Furthermore, concentrations of bromine and iodine in the river were found to increase with the direction of flow, and were correlated with the concentrations of artificial sweeteners and domestic sewage.
Article
Chemistry, Applied
Ediu Carlos da Silva Junior, Mehrnoosh Babaahmadifooladi, Karel Folens, Andre Rodrigues dos Reis, Luiz Roberto Guimaraes Guilherme, Tom Van de Wiele, Liesbeth Jacxsens, Gijs Du Laing
Summary: This study investigated the contents and bioaccessibility of trace elements in seaweed products available in Belgium. The results showed that 85% of the samples exceeded the permitted concentration levels for As, 39% for Cd, and 4% for I. Washing treatment significantly reduced the concentrations of all trace elements. In vitro simulation of gastrointestinal digestion revealed that the average bioaccessibility in the small intestine was: As (52%) > Ni (35%) > Pb (27%) > Cd (20%). People should practice washing to reduce the concentration and bioaccessibility of trace elements in seaweeds.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Environmental Sciences
Jennifer L. Griggs, Liang Chi, Nancy M. Hanley, Michael Kohan, Karen Herbin-Davis, David J. Thomas, Kun Lu, Rebecca C. Fry, Karen D. Bradham
Summary: Arsenic exposure can alter the gut microbiome in mice, and the composition of the microbiome can affect arsenic bioaccessibility. This study used a simulated gastrointestinal model to assess the effects of exposure to arsenic-contaminated soils on the gut microbiome and its impact on arsenic bioaccessibility. The results showed that exposure to arsenic did not change the gut microbiome composition in the colon phase, but it led to a decline in bacteria in the cecum phase. The variability in arsenic bioaccessibility may be influenced by the physicochemical properties of different soil types.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Gergana Novakova, Presian Bonev, Mary Duro, Rui Azevedo, Cristina Couto, Edgar Pinto, Agostinho Almeida
Summary: Patients on chronic hemodialysis therapy have normal serum iodine levels but significantly decreased serum bromine levels. This finding may be associated with sleep disturbances and fatigue in these patients. Further investigation is needed to determine the clinical significance.
Review
Food Science & Technology
Hualu Zhou, Yunbing Tan, David Julian McClements
Summary: The INFOGEST international consortium has developed an in vitro digestion model that is widely used to simulate the physicochemical processes of food digestion in the human gastrointestinal tract. This review provides an overview of the INFOGEST method and its applications in measuring macronutrient digestion, bioactive agent bioaccessibility, and changes in food structure and physical properties under gastrointestinal conditions. The review also discusses the application of the INFOGEST method in studying the fate of various types of foods and beverages, as well as its use in evaluating the digestibility of next-generation plant-based foods.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Zhiting Huang, Qiqi Chen, Kaixi Hu, Ruifen Zhang, Yang Yuan, Shan He, Qingzhu Zeng, Dongxiao Su
Summary: The study found that simulated gastrointestinal digestion can significantly increase the free phenolic content of seaweeds, and the total phenolic content of seaweeds also increases accordingly. The antioxidant activity of bound phenolics is superior to that of free phenolics.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Flora Christine Amagloh, Gaston Ampe Tumuhimbise, Benard Yada, Arnold Katungisa, Francis Kweku Amagloh, Archileo Natigo Kaaya
Summary: The percent bioaccessibility of phytochemicals and antioxidant activities of cooked sweet-potato storage roots of varying flesh colours was assessed. Generally, cooking increased the bioaccessibility of phytochemicals, except for vitamin C. Peeling the roots significantly increased the bioaccessibility of phenolics and flavonoids. Cooked roots had higher antioxidant activities than raw.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Engineering, Environmental
Xi-Mei Xue, Hong-Yu Wang, Xin-Wei Yu, Shilin Hu, Li-Jie Huang, Hui-Cheng Yang, Like Gong, Kai Yang, Hong-Bo Li, Yong-Guan Zhu
Summary: The metabolism and bioavailability of arsenosugars in edible seaweeds are influenced by gut microbiota. It was found that mice with disrupted gut microbiota excreted significantly higher levels of total arsenic in urine and lower levels in feces after consuming nori compared to normal mice. Arsenic speciation analysis revealed that phosphate arsenosugars in nori were mostly converted to arsenobetaine, while sulfonate arsenosugar in kelp remained intact in feces.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Ivan Alvarez-Freire, Pamela Cabarcos, Ana Maria Bermejo, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: The global market for new psychoactive substances (NPSs) is expanding, and the availability of drugs is increasing. Synthetic cannabinoids (SCRAs) are the largest group of NPSs and are often overlooked in illegal drug market control and toxicological-forensic analysis. Membrane-assisted solvent extraction (MASE) has been proposed as a method for extracting SCRAs from urine samples. The method was validated and found to be selective and sensitive, with low limits of quantification (LOQs).
ANALYTICAL METHODS
(2023)
Article
Biochemical Research Methods
Cristian Suarez-Oubina, Paloma Herbello-Hermelo, Natalia Mallo, Maria Vazquez, Santiago Cabaleiro, Ivone Pinheiro, Laura Rodriguez-Lorenzo, Begona Espina, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: This research focuses on using single-cell inductively coupled plasma-mass spectrometry (scICP-MS) to assess the associations of titanium dioxide nanoparticles (TiO2 NP) and silver nanoparticles (Ag NP) in cell lines derived from aquaculture species. The optimization studies aim to avoid high dissolved background, multi-cell peak coincidence, and possible spectral interferences. The results show that TiO2 NPs mainly interact with the outer cell membranes, while Ag NPs can enter the cells.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Elza Fonseca, Maria Vazquez, Laura Rodriguez-Lorenzo, Natalia Mallo, Ivone Pinheiro, Maria Ligia Sousa, Santiago Cabaleiro, Monica Quarato, Miguel Spuch-Calvar, Miguel A. Correa-Duarte, Juan Jose Lopez-Mayan, Mick Mackey, Antonio Moreda, Vitor Vasconcelos, Begona Espina, Alexandre Campos, Mario Jorge Araujo
Summary: In this study, the effects of citrate-coated TiO2 nanoparticles (TiO2 NPs) of two different primary sizes on the liver of flatfish turbot were investigated. The results showed that the abundance of lipid droplets in hepatocytes varied depending on the size of TiO2 NPs, with an increase in turbot exposed to smaller NPs and a depletion with larger NPs. Gene expression related to oxidative and immune responses as well as lipid metabolism was also influenced by TiO2 NPs. These findings emphasize the importance of scrutinizing the risks associated with exposure to NPs with distinct properties in aquatic organisms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Pamela Cabarcos-Fernandez, Maria Jesus Tabernero-Duque, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro, Ana Maria Bermejo-Barrera
Summary: Using ultrasounds, the extraction time for membrane-assisted solvent extraction (MASE) in isolating synthetic cathinones from urine has been shortened to 30 minutes. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used for the separation and determination of eleven synthetic cathinones. The developed method showed efficient extraction and pre-concentration of synthetic cathinones with LogP values higher than 2.0.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Juan Jose Lopez-Mayan, Blanca Alvarez-Fernandez, Elena Pena-Vazquez, Maria Carmen Barciela-Alonso, Antonio Moreda-Pineiro, Julie Maguire, Mick Mackey, Monica Quarato, Ivone Pinheiro, Begona Espina, Laura Rodriguez-Lorenzo, Pilar Bermejo-Barrera
Summary: A study was conducted to investigate the bioaccumulation of citrate-coated titanium dioxide nanoparticles in red (Palmaria palmata) and green (Ulva sp.) seaweed. The results showed that Ulva sp. had higher titanium concentrations than Palmaria palmata under the same exposure conditions. The titanium concentration in Ulva sp. reached its maximum after 28 days of exposure to 1.0 mgL(-1) of 5 nm TiO(2)NPs. The sizes and concentrations of TiO(2)NPs determined by SP-ICP-MS were similar for both seaweeds, suggesting that the titanium is mainly accumulated in Ulva sp. as ionic titanium or nanoparticles smaller than the limit of detection in size.
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Annarosa Mangone, Lorena C. C. Giannossa, Laura Nunez-Gonzalez, Paloma Herbello-Hermelo, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: Imaging studies using laser ablation-inductively coupled plasma mass spectrometry were conducted to analyze the presence and distribution of titanium (ionic titanium and/or titanium dioxide nanoparticles) in sea bream tissues after exposure to citrate-coated titanium dioxide nanoparticles. Calibration based on gelatine standards containing ionic titanium was used, and good repeatability and linearity of measurements were achieved. The optimized conditions resulted in a limit of detection of 0.087 μg g(-1) titanium.
Article
Chemistry, Multidisciplinary
Ivone Pinheiro, Monica Quarato, Antonio Moreda-Pineiro, Ana Vieira, Virginie Serin, David Neumeyer, Nicolas Ratel-Ramond, Sebastien Joulie, Alain Claverie, Miguel Spuch-Calvar, Miguel A. Correa-Duarte, Alexandre Campos, Jose Carlos Martins, Pilar Bermejo-Barrera, Marisa P. Sarria, Laura Rodriguez-Lorenzo, Begona Espina
Summary: Commercial ATO nanoparticles are relatively harmless to zebrafish and marine mussels, but they do affect the developmental parameters of zebrafish. Further research is needed on the accumulation of nanoparticles in the human body.
Article
Chemistry, Analytical
I. Alvarez-Freire, P. Cabarcos-Fernandez, N. C. Rubio, A. Moreda-Pineiro, M. J. Tabernero-Duque, I. Sanchez-Sellero, P. Bermejo-Barrera, A. M. Bermejo-Barrera
Summary: Hygrine and cuscohygrine have been proposed as markers for differentiating legal and illegal cocaine consumption. However, analytical methods for assessing coca leaf alkaloids in oral fluid are lacking in forensic toxicology laboratories worldwide. This study aims to optimize a separation method using solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry, resulting in improved detection and quantification limits for coca leaf alkaloids.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.