Article
Biochemistry & Molecular Biology
Sebastiano Intagliata, Angelo Spadaro, Miriam Lorenti, Annamaria Panico, Edy A. Siciliano, Sabrina Barbagallo, Benito Macaluso, Shyam H. Kamble, Maria N. Modica, Lucia Montenegro
Summary: A novel resveratrol triester derivative, RSVTR, was synthesized by combining resveratrol with trolox, exhibiting improved anti-glycation activity compared to resveratrol. RSVTR showed good chemical stability under various pHs and temperatures, with the greatest stability observed at pH 7.2 and 5 degrees C. The enhanced ability to inhibit the glycation process was attributed to RSVTR's better interaction with albumin due to increased topological polar surface area values and H-bond acceptor numbers.
Review
Food Science & Technology
Sakhi Ghelichi, Mona Hajfathalian, Betül Yesiltas, Ann-Dorit Moltke Sorensen, Pedro J. Garcia-Moreno, Charlotte Jacobsen
Summary: Emulsions play a vital role in food science, but their application in food production is hindered by physical and oxidative stability issues. This study aims to review oxidation and oxidative stability in emulsions, covering lipid oxidation reactions, measurement methods, and strategies to enhance stability. Different types of emulsions, including conventional and uncommon ones, as well as multiple emulsions, nanoemulsions, and Pickering emulsions, are considered. The comparative approach is used to explain oxidative processes in various parent and food emulsions.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Article
Environmental Sciences
Mouna Dammak, Hajer Ben Hlima, Slim Smaoui, Imen Fendri, Philippe Michaud, Mohamed Ali Ayadi, Slim Abdelkafi
Summary: This study investigated the potential of microalgae biomass as a source of anti-aging cosmetic cream with high antioxidant activity. Results showed that microalgae improved the antioxidant activity of the formulated skin creams and exhibited good stability.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Food Science & Technology
Zhiyu Li, Wenxiu Hu, Jiajia Dong, Fidelis Azi, Xiao Xu, Chuanhai Tu, Sijie Tang, Mingsheng Dong
Summary: In this study, curcumin-loaded Pickering emulsion was successfully produced using purified bacterial cellulose from fermented kombucha. The emulsion exhibited excellent stability and higher antioxidant activity compared to free curcumin, indicating its potential for functional applications.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Chemistry, Applied
Qais Ali Al-Maqtari, Abduljalil D. S. Ghaleb, Amer Ali Mahdi, Waleed Al-Ansi, Abeer Essam Noman, Minping Wei, Abdulqader Al-Adeeb, Weirong Yao
Summary: Ultrasonic treatment can improve the emulsifying properties of Pulicaria jaubertii extract water-in-oil emulsion, with 600 W showing optimal results. However, 400 W has positive effects on creaming index and antioxidant release. Storage at 4 degrees Celsius enhances the stability of the emulsion.
Article
Biochemistry & Molecular Biology
Rafael Flores, Shoaib Iqbal, Donald Sikazwe
Summary: In this study, we synthesized and partially evaluated 20 amides as potential drugs for treating Alzheimer's disease. Compound 8 showed promising characteristics, including affinity for sigma-1, inhibition of HDAC-6, and antioxidant activity, making it suitable for further research and optimization.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Gerui Ren, Ying Zhu, Jieyu Shi, Jiacheng Liu, Ying He, Yufan Sun, Yujing Zhan, Junfei Lv, Min Huang, Hujun Xie
Summary: In this study, an antioxidant Pickering emulsion stabilized by zein-grafted resveratrol and pectin complex particles was prepared. The emulsion showed excellent physical stability and outstanding ability to prevent lipid oxidation. Adjusting the wettability of the particles and forming a protective film on the surface of oil droplets contributed to the stability of the emulsion.
Article
Food Science & Technology
Chenyue Liu, Shasha Cheng, Haitao Wang, Mingqian Tan
Summary: In this study, oil-in-water Pickering emulsions were prepared using Haematococcus Pluvialis protein (HPP) particles as an emulsifier. The emulsion showed high stability with an internal oil phase as high as 70% and average oil droplet size of 20 μm. The emulsion stabilized by 2.5% HPP and 70% oil phase ratio exhibited the best stability, even under acidic conditions, high ionic strength, and low or high temperatures. Additionally, the HPP-stabilized emulsion inhibited oil phase oxidation during storage due to the presence of astaxanthin (AST) in HPP.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Energy & Fuels
Jader Martinez-Giron
Summary: This study evaluated the effects of adding sweet red pepper oleoresin and tree tomato juice at different concentrations to vegetable margarine. The results showed that the addition of these natural extracts significantly increased the bioactive compounds and antioxidant activity of the margarine. Physicochemical and microbiological tests confirmed that the developed margarine met quality standards. The margarine formulated with 200 ppm of sweet red pepper oleoresin and 10% of tree tomato juice received the best sensory evaluation.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Chemistry, Multidisciplinary
Przemyslaw Siejak, Grazyna Neunert, Wojciech Smulek, Krzysztof Polewski
Summary: In this study, the influence of different bird cherry extracts on the oxidative stability of a linoleic acid emulsion was investigated. The results showed that the acetone extract was the most effective in terms of oxidation stability and time degradation tests. Additionally, the addition of gallic acid did not always have a positive effect on these properties.
APPLIED SCIENCES-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Martin Almendinger, Franziska Saalfrank, Sascha Rohn, Elke Kurth, Monika Springer, Daniel Pleissner
Summary: Microalgae and cyanobacteria are rich sources of high-value pigments and phenolic compounds with antioxidant capacity, which can be utilized in food, cosmetics, and pharmaceutical industries. Different species of microalgae and cyanobacteria were analyzed for their antioxidant capacity, revealing variations in the content of phenolic compounds and water-soluble/lipid-soluble compounds. Pre-treatment methods such as cell disruption were shown to double the yields of antioxidant compounds, emphasizing the importance of effective extraction methods.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Microbiology
Maja Chochevska, Elizabeta Jancovska Seniceva, Sanja Kostadinovic Velickovska, Galaba Naumova-Letia, Valentin Mirceski, Joao Miguel F. Rocha, Tuba Esatbeyoglu
Summary: The study found that all traditional homemade fruit vinegars had at least 10 times higher antioxidant activity than commercial fruit vinegars. Rose hip homemade vinegar showed the highest antioxidant capacity, while apple and persimmon homemade vinegars had the lowest levels of antioxidants, indicating the importance of fruit type in vinegar production. The use of traditional processes for fruit vinegar production showed promise in producing high-quality vinegars with high levels of health-promoting antioxidant capacities.
Article
Biochemistry & Molecular Biology
Dilara Yalmanci, Enes Dertli, Zeynep Hazal Tekin-Cakmak, Salih Karasu
Summary: This study aimed to investigate the potential usage of exopolysaccharide (EPS) produced by Leuconostoc lactis GW-6 species as an emulsifier in a low-fat mayonnaise by the formation of a complex with whey protein isolate (WPI) to improve rheological properties, emulsion, and oxidative stability. The results showed that the EPS and WPI interaction can significantly affect the rheological properties, emulsion, and oxidative stability of mayonnaise samples.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Nutrition & Dietetics
Jian Zhang, Huien Zhang, Liping Liu, Zhongfa Chen
Summary: Curcumin emulsions covered with cellulose particles of different structures were prepared successfully. The stability and antioxidant properties of the emulsions were influenced by the hydrolysis time of the cellulose particles. A longer hydrolysis time resulted in better stability and scavenging activity.
FRONTIERS IN NUTRITION
(2022)
Article
Marine & Freshwater Biology
Marie-Jeanne Perrot-Minnot, Aude Balourdet, Olivier Musset
Summary: The study focused on the anesthetic effects of MS-222 and Eugenol in the freshwater amphipod Gammarus pulex, demonstrating the sedative and analgesic-like effects of MS-222, with Eugenol requiring a higher concentration for similar efficacy. Additionally, a new semi-automated electric shock device was used to induce nociception, offering a standardized and flexible protocol for studying nociceptive response and anesthesia in aquatic organisms.
AQUATIC TOXICOLOGY
(2021)
Article
Chemistry, Applied
Jens C. Meyer, Tim Birr, Inga Hennies, Detlev Wessels, Karin Schwarz
Summary: Oats are susceptible to Fusarium fungi, resulting in mycotoxin contamination. De-hulling alone may not be sufficient to remove mycotoxin contamination in oats.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2022)
Article
Chemistry, Applied
L. J. G. Hoppenreijs, L. Fitzner, T. Ruhmlieb, T. R. Heyn, K. Schild, A-J van der Goot, R. M. Boom, A. Steffen-Heins, K. Schwarz, J. K. Keppler
Summary: This study explores the formation of amyloid-like aggregates under different environmental and processing conditions, revealing key mechanisms that influence the morphology of these aggregates. The findings suggest that the flexibility and morphology of the aggregates are influenced by factors such as assembly speed, protein destabilization, and post-processing methods, which can lead to the formation of higher order structures with various applications.
FOOD HYDROCOLLOIDS
(2022)
Article
Nutrition & Dietetics
Louisa Mewes, Carina Knappe, Christian Graetz, Juliane Wagner, Tobias J. Demetrowitsch, Julia Jensen-Kroll, Karim Mohamed Fawzy El-Sayed, Karin Schwarz, Christof E. Dorfer, Stefan Schreiber, Matthias Laudes, Dominik M. Schulte
Summary: Vitamin C and ω-3 fatty acid Docosapentaenoic acid may play a role in the pathophysiology of human periodontitis.
Article
Gastroenterology & Hepatology
Lea Henneke, Kristina Schlicht, Nadia A. Andreani, Tim Hollstein, Tobias Demetrowitsch, Carina Knappe, Katharina Hartmann, Julia Jensen-Kroll, Nathalie Rohmann, Daniela Pohlschneider, Corinna Geisler, Dominik M. Schulte, Ute Settgast, Kathrin Tuerk, Johannes Zimmermann, Christoph Kaleta, John F. Baines, Jane Shearer, Shrushti Shah, Grace Shen-Tu, Karin Schwarz, Andre Franke, Stefan Schreiber, Matthias Laudes
Summary: Recent research has found that Parasutterella plays an important role in the development of type 2 diabetes and obesity. This study analyzed a European cohort and validated the results in a Canadian cohort. The findings showed that Parasutterella was positively associated with BMI and type 2 diabetes, and its abundance was related to the intake of carbohydrates. Furthermore, the study found a reduction in L-cysteine and activation of the fatty acid biosynthesis pathway, suggesting potential mechanisms for the development of type 2 diabetes and obesity.
Article
Nutrition & Dietetics
Nathalie Rohmann, Liasita Munthe, Kristina Schlicht, Corinna Geisler, Tobias J. Demetrowitsch, Corinna Bang, Julia Jensen-Kroll, Kathrin Tuerk, Petra Bacher, Andre Franke, Karin Schwarz, Dominik M. Schulte, Matthias Laudes
Summary: This study found that obesity and metabolic abnormalities are more common in individuals with allergies, especially contact allergies. Contact allergies were strongly associated with hyperlipidemia and dietary intake of polyunsaturated fatty acids, while hay fever was linked to low physical activity, shorter sleep duration, and changes in gut microbiota composition. Genetic predisposition to hyperlipidemia was found to be associated with both contact allergies and hay fever.
Article
Plant Sciences
Jay Jethva, Sophie Lichtenauer, Romy Schmidt-Schippers, Anja Steffen-Heins, Gernot Poschet, Markus Wirtz, Joost T. van Dongen, Juergen Eirich, Iris Finkemeier, Wolfgang Bilger, Markus Schwarzlaender, Margret Sauter
Summary: Submergence stress is a growing problem for global agriculture, and the cellular mechanisms for reoxygenation stress management are not fully understood. Our study on Arabidopsis revealed that alternative NADH dehydrogenases (NDs) play a crucial role in the management of anoxia-reoxygenation stress.
Article
Plant Sciences
Serhat Sezai Cicek, Anna Lais Pfeifer Barbosa, Arlette Wenzel-Storjohann, Jorge Federico Orellana Segovia, Roberto Messias Bezerra, Frank Soennichsen, Christian Zidorn, Isamu Kanzaki, Deniz Tasdemir
Summary: This study investigated the phytochemistry and bioactivity of Vouacapoua americana, an economically important tree in the Amazon region. Several potentially pharmacologically active compounds were identified, and the structure of one compound was revised. The findings contribute to the development of drugs from Amazonian medicinal plants.
Article
Chemistry, Physical
Jacqueline Lux, Helena Kieserling, Joerg Koop, Stephan Drusch, Karin Schwarz, Julia K. Keppler, Anja Steffen-Heins
Summary: Engineered fibril solutions from whey protein beta-lactoglobulin containing amyloid and non-amyloid fractions exhibit improved foaming capacity due to the synergistic interactions at the air-water interface. The non-amyloid fraction shows faster migration and adsorption, while the amyloid fraction has higher surface hydrophobicity, promoting attraction between fibrils. The incorporation of non-amyloid fraction increases the density and stability of the fibrillar film. Only small amounts of amyloid aggregates are required to stabilize foams due to the interplay between amyloid and non-amyloid proteins at the air-water interface.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Polymer Science
Shuo Li, Katrin Bamberg, Yuzhou Lu, Frank D. Soennichsen, Anne Staubitz
Summary: In this study, linear photoresponsive poly(thioether)s containing diazocine moieties in the polymer backbone were synthesized and their photoisomerization behavior was investigated. The resulting polymers showed reversible photoswitchability between the (Z)- and (E)-configurations. The study highlights the potential use of diazocine as an elongating actuator in macromolecular systems and smart materials.
Article
Biochemistry & Molecular Biology
Luise Schlotterose, Mariya S. Pravdivtseva, Frowin Ellermann, Olav Jansen, Jan-Bernd Hoevener, Frank D. Soennichsen, Francois Cossais, Ralph Lucius, Kirsten Hattermann
Summary: The role of microglia cells in neurodegenerative diseases has been increasingly recognized. Activation of microglia cells is believed to be involved in the progression of diseases like Alzheimer's or Parkinson's disease. In this study, the researchers investigated the effects of the natural antioxidant resveratrol on human microglia cells. They found that resveratrol reduced inflammation, increased the release of insulin-like growth factor 1, decreased glucose uptake, lowered mitochondrial activity, and attenuated cellular metabolism in microglia cells. The study focused on changes in metabolism without any external stressors and demonstrated the potential protective effects of resveratrol against neuroinflammation.
Article
Chemistry, Applied
Kerstin Schild, Frank D. Soennichsen, Dierk Martin, Vasil M. Garamus, Atze Jan Van der Goot, Karin Schwarz, Julia K. Keppler
Summary: The non-covalent interactions between phenolics and proteins are difficult to identify, leading to contradictory results in the literature. In this study, we use advanced methods to clarify the interactions between tea phenolics (EGCG, epicatechin, and gallic acid) and whey protein ll-lactoglobulin. The results show that all rings of EGCG can interact with native ll-lactoglobulin, indicating a multidentate binding. However, specific interactions were found for epicatechin only at higher protein:epicatechin molar ratios, and no evidence of interaction was found for gallic acid. Therefore, gallic acid and epicatechin can be added to native BLG without causing modification.
Article
Chemistry, Organic
Arne Brahms, Andrey N. Pravdivtsev, Lynn Thorns, Frank D. Sonnichsen, Jan-Bernd Hovener, Rainer Herges
Summary: In this study, a novel synthesis for C-13, deuterated ketocarboxylic acids was reported, as well as an improved synthesis of 1-C-13-vinyl pruvate-d6. The addition process was monitored through hydrogenation with parahydrogen. This synthesis opens up new possibilities for hyperpolarization and metabolic imaging using parahydrogen.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Tobias Paschelke, Eicke Trumpf, David Grantz, Malte Pankau, Niclas Grocholski, Christian Naether, Frank D. Soennichsen, Anna J. Mcconnell
Summary: In this study, a family of (Fe4L6)-L-II spin-crossover cages based on 2,2'-pyridylbenzimidazoles was reported, and it was found that subtle ligand modifications can lower the spin crossover temperature in CD3CN by up to 186 K. Comparing different pairs of cages, it was observed that CH3 substituents on either the coordination motif or phenylene linker can lower the spin-crossover temperature by different degrees, attributed to electronic effects, steric effects, and a combination of both. The understanding of the interplay between ligand modifications from this study could contribute to the improved rational design of spin-crossover cages.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.