Article
Plant Sciences
Yanfen Niu, Qiang Li, Caixia Tu, Na Li, Lihui Gao, Hua Lin, Zhenyu Wang, Zhihong Zhou, Ling Li
Summary: Hyperuricemia is a well-known risk factor for gout, hypertension, and diabetes, but there are limited drugs available for its treatment. Recent research has focused on discovering new uric acid-lowering agents from plants and foods. This study found that alpha-mangostin, extracted from the pericarp of mangosteen, effectively lowered urate levels and promoted uric acid excretion in hyperuricemic animals. The mechanism of action was found to be related to the decrease in GLUT9 protein levels in the kidneys. Alpha-mangostin shows potential as a new anti-hyperuricemic agent.
JOURNAL OF NATURAL PRODUCTS
(2023)
Article
Food Science & Technology
Karunrat Sakulnarmrat, Wuttichai Sittiwong, Izabela Konczak
Summary: This study encapsulated mangosteen pericarp anthocyanin-rich extract using spray drying with MD20:PEC and MD20:IN combinations, achieving high encapsulation efficiency and anthocyanin content. The encapsulated powders had a crystalline-mixed amorphous structure and demonstrated high thermal stability at temperatures suitable for Lactobacillus bulgaricus.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Agronomy
Nipaporn Thammachote, Kanlaya Sripong, Apiradee Uthairatanakij, Natta Laohakunjit, Sontaya Limmatvapirat, Gang Ma, Lancui Zhang, Masaya Kato, Pongphen Jitareerat
Summary: The main problem in the postharvest period of mangosteen is fruit rot caused by Lasiodioplodia theobromae, and silver nanoparticles (AgNPs) were found to be effective in inhibiting fungal infection. In in vitro tests, 270 ppm AgNPs completely inhibited mycelium growth and spore germination in L. theobromae. In in vivo tests, treatment with AgNPs significantly decreased the disease index in mangosteen fruit, while inducing plant defense-related enzyme activities and maintaining fruit quality.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Mingoo Bae, Seung Yon Han, Eun-Sun Kim, Byung Hoon You, Young-Mi Kim, Jungsook Cho, Young-Won Chin, Young Hee Choi
Summary: The combination of water extract of mangosteen pericarp (WMP) and donepezil (DNP) for Alzheimer's disease (AD) treatment showed a stronger inhibitory effect on neurotoxicity induced by A beta((25-35)) compared to donepezil alone. WMP increased the concentration of donepezil in the brain without affecting systemic exposure, suggesting a potential therapeutic benefit for AD.
Article
Nutrition & Dietetics
Emily P. Laveriano-Santos, Camila Arancibia-Riveros, Anna Tresserra-Rimbau, Sara Castro-Barquero, Ana Maria Ruiz-Leon, Ramon Estruch, Rosa Casas, Patricia Bodega, Mercedes de Miguel, Amaya de Cos-Gandoy, Jesus Martinez-Gomez, Carla Rodriguez, Gloria Santos-Beneit, Juan M. Fernandez-Alvira, Rodrigo Fernandez-Jimenez, Rosa M. Lamuela-Raventos
Summary: This study found that higher intake of flavonoids from cocoa-based products was associated with lower adiposity parameters and a lower probability of presenting abdominal obesity.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Yeonsoo Oh, Ha Thi Thu Do, Sunyoung Kim, Young-Mi Kim, Young-Won Chin, Jungsook Cho
Summary: This study found that mangosteen pericarp water extract (MPW) exerts memory-enhancing effects through antioxidative neuroprotection and anti-apoptotic action. Oral administration of MPW to scopolamine-treated mice significantly decreased latency time and increased swimming time in the target quadrant.
Article
Biochemistry & Molecular Biology
Sakeena Si Yu Tan, Meyammai Shanmugham, Yu Ling Chin, Jia An, Chee Kai Chua, Eng Shi Ong, Chen Huei Leo
Summary: This study extracts phytochemical compounds from mangosteen pericarp using pressurized hot water extraction (PHWE) and investigates its biological effects on endothelial cells using RNA sequencing. Results show that extraction at a temperature of 120 degrees Celsius yields the highest concentrations of key phytochemical compounds and improves antioxidant capacity. Treatment of endothelial cells with the extract activates the AMPK signaling pathway and affects biological processes related to steroid biosynthesis and metabolism. Overall, this study provides important insights into the potential beneficial effects of phytochemical compounds from mangosteen pericarp on cardiometabolic health.
Article
Agriculture, Multidisciplinary
Junbin Wei, Xin Zhang, Ruihao Zhong, Bin Liu, Xuelian Zhang, Fang Fang, Zhaoqi Zhang, Xuequn Pang
Summary: After harvest, litchi pericarp quickly turns brown, with decreases in (-)-epicatechin and procyanidins contents. The enzyme ADE/LAC plays a critical role in catalyzing the conversion of procyanidins, contributing to the browning process of the pericarp.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Engineering, Environmental
Saowaluk Boonyod, Weraporn Pivsa-Art, Phornwalan Nanthananon, Yong Ku Kwon, Sommai Pivsa-Art
Summary: This research investigates the antibacterial activity of a biodegradable nonwoven fabric coated with mangosteen pericarp (MP) extract, due to its eco-friendliness and antimicrobial property. The experiment showed that the MP extract inhibited the growth of Escherichia coli and Staphylococcus aureus. The tensile strength of the fabric was positively correlated with the MP extract concentration, while the elongation at break showed an inverse correlation. Higher concentrations of MP extract had minimal effect on the fabric's biodegradability. Overall, the MP extract shows promising potential as an antibacterial agent.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Food Science & Technology
Bianca R. Albuquerque, Maria Ines Dias, Jose Pinela, Ricardo C. Calhelha, Tania C. S. P. Pires, Maria Jose Alves, Rubia C. G. Correa, Isabel C. F. R. Ferreira, Maria Beatriz P. P. Oliveira, Lillian Barros
Summary: The ripe mangosteen pericarp contains seven organic acids, three tocopherol isomers, four fatty acids, and fifteen non-xanthone phenolic compounds. The most efficient extraction of phenolic compounds was achieved using hydroethanolic extract (MT80), followed by ethanolic extract (MTE), and then aqueous extract (MTW). Both MT80 and MTE extracts exhibited antioxidant and antibacterial activities. MTW did not show anti-inflammatory properties, while MTE and MT80 inhibited tumor cell lines.
Article
Food Science & Technology
Xiaofang Li, Haoze Chen, Yan Jia, Jinming Peng, Chunmei Li
Summary: In this study, an efficient method for enriching polyphenols from mangosteen pericarp (MPPs) was developed, and its inhibitory effects on starch digestion were evaluated. The results showed that MPPs had inhibitory activity on alpha-amylase and could reduce blood glucose peak and glucose response AUC.
Article
Agronomy
Bin Liu, Qiunan Zhu, Xianfang Zhou, Xuelian Zhang, Zhaoxia Dang, Shuxing Liang, Ganting Li, Zhaoqi Zhang, Fang Fang, Xuequn Pang
Summary: The study found that during the browning of longan pericarp, the activity level of the laccase LAC14-4 increased, leading to the polymerization of procyanidins and causing the pericarp to turn brown.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Haocheng Liu, Yuqian Tang, Zhaowen Deng, Jiguo Yang, Dan Gan
Summary: A process for transforming litchis' polymeric proanthocyanidins (LPPCs) using Lactobacilli has been established to enhance their antioxidative properties. Lactobacillus plantarum was used to enhance the transformation effect, achieving a transformation rate of 78.36%. The products showed significantly higher in vitro antioxidative activity compared to LOPCs and LPPCs, with a scavenging activity for DPPH free radicals that was 1.71 times higher than LOPCs, and a rate of inhibiting CD-POV that was 2.0 times higher than LPPCs.
Article
Veterinary Sciences
Suman Lata, Pushpendra Koli, Sultan Singh, B. K. Bhadoria, Umesh Chand, Yonglin Ren
Summary: Two novel proanthocyanidins were isolated from the leaves of Anogeissus pendula. They exhibit a tendency to interact with proteins due to their molecular weight, chemical structure, and conformation. In vitro testing showed significant inhibition activities against ruminal enzymes. These newly discovered proanthocyanidins have potential roles in improving feed conversion ratios and in drug development.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Bira Arumndari Nurrahma, Tu-Hsueh Yeh, Rong-Hong Hsieh, Shu-Ping Tsao, Chia-Wen Chen, Yen-Peng Lee, Chun-Hsu Pan, Hui-Yu Huang
Summary: The study suggests that mangosteen pericarp extract may delay the progression of Parkinson's disease by counteracting oxidative stress and improving gut microbiota composition.
Article
Food Science & Technology
Jing Liu, Yan Yu, Yiping Zhao, Liangyu Jiang, You Zhou, Dejian Huang, Li Xu
Summary: The relationship between the cholesterol-lowering, antioxidant, and DNA damage protection activities of different solvent extracts from Morus alba L. were studied. It was found that the polyphenol and flavonoid contents in the extracts were positively correlated with these biological activities. The extracts have potential as natural sources of anti-hypercholesterolemia, antioxidants, and DNA damage protection, with the potential use in functional food and health products.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Food Science & Technology
Song Zhu, Bo Liu, Fang Wang, Dejian Huang, Fang Zhong, Yue Li
Summary: The study found that the blend of cassava starch and EGCG had a more ordered crystal structure and stronger thermal stability compared to native starch, protecting EGCG from oxidation and allowing controlled-release of EGCG by the starch.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
Joanne Yi Hui Toy, Yuyun Lu, Dejian Huang, Keisuke Matsumura, Shao-Quan Liu
Summary: Food manufacturers are increasingly using enzymes to improve yield and product quality in fruit-based products. Enzymatic hydrolysis treatment helps achieve viscosity reduction, clarification, better nutritional quality, and enhanced sensory characteristics. Non-Saccharomyces yeasts are being employed to produce complex flavor profiles in fermented fruit-based products. Fermented probiotic fruit juice is also discussed as an alternative to dairy-based probiotic products.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Analytical
Mingtai Sun, Tian Wang, Xin Yang, Huan Yu, Suhua Wang, Dejian Huang
Summary: A new fluorescent probe BV-1 based on BODIPY group was synthesized and demonstrated to detect viscosity in living cells with high selectivity and sensitivity. The probe showed significant enhancement in fluorescence with redshift in emission wavelength under high viscosity conditions, providing efficient ways for the development of viscosity probes and monitoring of intracellular viscosity properties and functions.
Review
Agriculture, Multidisciplinary
Xiang Wang, Yujia Cao, Siyu Chen, Jiachen Lin, Jinsong Bian, Dejian Huang
Summary: Flavones are important bioactive constituents in foods, with anti-inflammatory properties. The position of hydroxyl groups (-OH) is crucial for determining the anti-inflammatory activity of flavones.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Food Science & Technology
Song Zhu, Shan Wang, Lingbo Wang, Dejian Huang, Shangwei Chen
Summary: In this study, a novel ACE inhibitory peptide HPVTGL derived from rape bee pollen protein was identified and found to have stable inhibitory activity and antihypertensive effects. Molecular docking and animal experiments supported its potential for use in functional foods or pharmaceutical agents against hypertension.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Physics, Applied
Yan Kong, Shujian Ong, Mei Hui Liu, Hanry Yu, Dejian Huang
Summary: This study successfully fabricated edible microbeads using food-grade sodium alginate and enhanced their cytoaffinity with gelatin coatings. The modified microbeads have self-fluorescence and can be used as microcarriers for cell culture and meat production.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Chemistry, Applied
Yue Li, Yihan Yang, Song Zhu, Bo Liu, Fang Zhong, Dejian Huang
Summary: In this study, OS-TPs complexes were prepared and their effects on the physical and oxidative stability of oil-water emulsion were investigated. The study showed that the OS-TPs complex effectively reduced the interfacial tension and improved the emulsifying ability of OSA starch. The complex also exhibited higher oxidative stability and a more stable structure compared to a simple mixture of tea polyphenols and OSA starch emulsion.
FOOD HYDROCOLLOIDS
(2023)
Article
Food Science & Technology
Liping Hu, Yue Li, Xiang Huang, Chaodong Du, Dejian Huang, Xiumei Tao
Summary: This study investigated the effect of co-fermentation with lactic acid bacteria and yeast on the wheat protein digestibility of crackers and explored the mechanism of protein changes during fermentation. Co-fermentation significantly improved the protein digestibility of crackers and increased the content of free amino acids. It also had a significant effect on the sourdough during fermentation. These findings provide an important theoretical basis for the application of lactic acid bacteria and yeast co-fermentation in crackers.
Article
Food Science & Technology
Yan Kong, Dejian Huang
Summary: Researchers have developed an edible microbead with pumpkin seed protein coating, which shows strong cytoaffinity and can be used as extracellular matrix material for cell-based meat culture.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Baoshuang Du, Shan Wang, Song Zhu, Yue Li, Dejian Huang, Shangwei Chen
Summary: In this study, the liposolubility of dihydromyricetin (DHM) was improved by acylating it with different fatty acid vinyl esters, resulting in the synthesis of five DHM acylated derivatives with different carbon chain lengths and lipophilicity. The relationship between the lipophilicity and antioxidant activities of DHM and its derivatives was evaluated using oil and emulsion models. The results showed that DHM derivatives with different lipophilicity exhibited various antioxidant activities in different antioxidant models.
Article
Food Science & Technology
Peiyu Wang, Yue Li, Ruipeng Yu, Dejian Huang, Shangwei Chen, Song Zhu
Summary: The effects of different drying methods on the selenium content and bioaccessibility of Se-rich plants were studied. The study found that far-infrared drying had the lowest selenium loss rate, while freeze vacuum drying and vacuum drying had the lowest Se retention and bioaccessibility.
Article
Chemistry, Applied
Jingxin Uma Tay, Chaoying Zhou, Hui Wen Lee, Yuyun Lu, Dejian Huang
Summary: This study developed plant-protein based salmon mimics using 3D printing of plant protein-based food inks and post-printing transglutaminase treatment. The structural stability and texture of the mimic were achieved through high pressure homogenization and gelation. This research is significant for the development of plant-based meat substitutes.
FOOD HYDROCOLLOIDS
(2023)
Article
Food Science & Technology
Yan Kong, Nien Ping Toh, Yuyao Wu, Dejian Huang
Summary: Cultured meat is a promising alternative to traditional meat production, offering benefits such as reduced environmental impact, animal suffering, and food safety risks. Researchers have developed novel microcarriers based on chickpea protein hydrolysates that exhibit excellent cytoaffinity and proliferation for various cultured cells. These microcarriers also enable cell differentiation into muscle or fat cells, making them a cost-effective and scalable substrate for cultured meat production.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Nanoscience & Nanotechnology
Linzhi Jing, Xiang Wang, Bin Leng, Ningping Zhan, Hang Liu, Shifei Wang, Yuyun Lu, Jie Sun, Dejian Huang
Summary: Scaffold-based 3D cell culture systems are gaining attention in cell biology, tissue engineering, and drug screening. Microscale fibrous scaffolds with nanoscale features were fabricated and shown to promote cell adhesion, migration, proliferation, and tissue formation. Upregulation of key biomarkers in cancer cells seeded on these scaffolds suggests their potential as 3D tumor models for cancer research and drug screening.
ACS APPLIED BIO MATERIALS
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
