Article
Chemistry, Analytical
Shiyong Chen, Jie Wang, Zhikun Shang, Yun Ding, Aiguo Hu
Summary: A fluorescent sensor array based on conjugated polymers (CPs) has been developed for the detection of tetracyclines (TCs), which are known environmental pollutants. The sensor array can effectively differentiate TCs at a low detection concentration and quantitatively distinguish different concentrations of TCs. The array has also successfully demonstrated the potential for detecting TCs in aqueous solutions, expanding its applications in practical environments.
Article
Food Science & Technology
Francisco Oiram Filho, Morgana Pereira Mitri, Guilherme Juliao Zocolo, Kirley Marques Canuto, Edy Sousa de Brito
Summary: This study describes the development of a high-performance liquid chromatography method for quantifying anacardic acids in cashew peduncles. The method showed satisfactory precision, linearity, repeatability, and selectivity, with detection and quantification limits of 0.18 and 0.85 μg/mL, respectively. Analysis of different cashew clones revealed varying levels of anacardic acid content.
Article
Chemistry, Multidisciplinary
Chang-Seob Seo, Hyeun-Kyoo Shin
Summary: A simultaneous analysis method for quality assessment of the herbal medicine formula DHGST has been developed and validated, providing basic data for other herbal medicine prescriptions.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Analytical
Abdelghani Mahmoudi, Silvia De Francia, Prasanta Paul
Summary: This study developed and validated a cost-effective and reliable HPLC method for quantifying clarithromycin in tablets. The proposed method showed good linearity, precision, accuracy, robustness, and specificity, and was comparable to capillary electrophoresis and bioassay methods. Therefore, it can be used as an alternative method for routine quality control of clarithromycin, especially when other methods are not accessible.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Analytical
Sophie Catanese, Raoul K. Khanna, Antoine Lefevre, Hugo Alarcan, Pierre-Jean Pisella, Patrick Emond, Helene Blasco
Summary: To apply metabo-lipidomics in ophthalmological and systemic diseases, it is necessary to standardize the preanalytical and analytical steps in human tears. This study compared different methods for each step of the workflow and found that methanol/water extraction provided the best results for metabolomics, while Folch extraction was superior for lipidomics. The use of microcapillary glass tube for sampling was superior to Schirmer strip for metabolomics. A volume of 5 mu L provided satisfactory metabo-lipidomic coverage. These findings will contribute to improving the metabo-lipidomic workflow in human tears for the identification of new biomarkers.
Article
Chemistry, Analytical
Ronghua Ni, Xiao Du, Rongrong Huang, Wenyi Wu, Jingqiu Xu, Xiaofei Ma, Liangliang Cai
Summary: A reliable reversed-phase high-performance liquid chromatography method was developed for the detection of related substances in the bulk drug of abemaciclib. This method exhibits good system suitability, specificity, precision, and stability, and is of great significance in the quality control of this drug.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Environmental Sciences
Fan Wang, Yishan Lu, Junming Cao
Summary: This study investigated the effects of oxytetracycline (OTC) on marine fish and its impact on intestinal health and antibiotic residue. The results showed that OTC exposure had no significant effects on fish growth, but caused liver and intestine atrophy. OTC exposure also impaired intestinal health and induced oxidative stress, inflammation, and apoptosis. However, withdrawal treatment improved intestinal health status. OTC residue was found mainly in the liver, kidney, and spleen, and decreased with withdrawal treatment. The consumption of OTC-treated or withdrawal-treated pearl gentian grouper muscle posed no significant health risks according to the target hazard quotient assessment.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Biochemical Research Methods
Sara Morello, Sabina Pederiva, Rosa Avolio, Stefania Squadrone, Maria Cesarina Abete, Daniela Marchis
Summary: The aim of this study was to develop and validate a reliable LC-MS/MS method for the determination and quantification of tetracycline residues in PAPs. The LC-MS/MS method exhibited satisfactory performance and can be used as a confirmatory method for the presence of tetracycline residues in PAPs. To ensure safety in the feed and food chain and to avoid misuse and increased antibiotic resistance pressure on the environment, regulation and control over antibiotic occurrence in PAPs should be implemented.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yue Zhang, Yang Li, Xiaoxia Liu, Ying Sun
Summary: This study established a method for detecting 21 target antibiotics in agricultural soil samples using ultra-high performance liquid chromatography with tandem mass spectrometry, with high extraction and detection efficiency. Validation of the method's selectivity, sensitivity, and reliability provided valuable information on analyzing the degree of antibiotic contamination in agricultural soils.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Food Science & Technology
Dehui Wen, Rong Shi, Haiming He, Rundong Chen, Yingzi Zhang, Rong Liu, Hong Chen
Summary: This study aimed to determine the presence of promethazine (PMZ) and its metabolites, promethazine sulfoxide (PMZSO) and monodesmethyl-promethazine (Nor(1)PMZ), in different swine tissues. A sample preparation method and an analysis using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) were established and validated. The method showed good sensitivity, with limits of detection (LOD) and limits of quantification (LOQ) of 0.05 µg/kg and 0.1 µg/kg, respectively. The study also demonstrated good linearity and average recoveries for the target compounds, making it suitable for monitoring veterinary drug residues in animal-derived foods.
Article
Agriculture, Multidisciplinary
Rita Vegh, Csilla Soros, Nandor Majercsik, Laszlo Sipos
Summary: A multiresidue method for pesticide determination in bee pollen was developed and validated, and it was found that some samples contained banned pesticides, although they did not pose an acute risk on honeybees.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yoapoing Shi, Dipendu Mandal, Zhenbin Zhang, Yufen Zhao
Summary: We have developed a new protocol for determining D/L amino acids using a chiral phosphinate derivatization. (RP)-L-Menthyl phenylphosphinate successfully labeled eighteen pairs of amino acids except for Cys, and the chirality of amino acids was discriminated by 31P NMR. Seventeen pairs of amino acids were separated in 45 minutes using a C18 column, with resolution values ranging from 2.01 to 10.76. The lowest limit of detection was 10 pM in parallel reaction monitoring, highlighting the potential of chiral phosphine oxides in future chiral metabolomics.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jonas Carneiro Cruz, Israel Donizeti de Souza, Caroline Fernandes Grecco, Eduardo Costa Figueiredo, Maria Eugenia Costa Queiroz
Summary: Bioanalysis faces challenges in sample preparation due to the complexity of biological samples, but recent trends focus on miniaturization, automation, and high-throughput performance. Column switching liquid chromatography, as a multidimensional method, can improve sensitivity and accuracy, reduce organic solvent consumption, and enhance sample handling efficiency.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Article
Chemistry, Analytical
Bert Vankeerberghen, Francois Parmentier, Gert Desmet
Summary: The efficiency of liquid chromatography separations can be greatly improved by using a bundle of parallel capillary tubes instead of packed bed columns. However, the presence of polydispersity caused by small differences in capillary diameter ruins this potential. The concept of diffusional bridging that introduces a cross talk between adjacent capillaries has been proposed to solve this issue, and this study provides the first experimental proof and validation of the theory behind it. The observed reduction in dispersion aligns well with theoretical predictions, suggesting that this theory could lead to the design of a new generation of chromatographic beds with unprecedented performance.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Abhishesh Kumar Mehata, M. Nikitha Lakshmi Suseela, Patharaj Gokul, Ankit Kumar Malik, Matte Kasi Viswanadh, Chandrashekhar Singh, Joseph Selvin, Madaswamy S. Muthu
Summary: Antibiotics play a crucial role in preventing and mitigating infectious diseases, but their mass production has led to the accelerated development of antimicrobial resistance. Conventional wastewater treatment methods are inefficient in removing antibiotics, and it is essential to develop highly efficient analytical methods for quantifying antibiotic residues in the environment. This review provides an overview of sampling techniques, purification and enrichment methods for antibiotics from environmental matrices, as well as various analytical methods for the quantification of extracted antibiotics.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Felipe R. N. Silva, Andrea R. Bortolotte, Patricia A. de C. Braga, Felix G. R. Reyes, Adriana P. Arisseto-Bragotto
FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
(2020)
Article
Food Science & Technology
Luisa Freire, Patricia A. C. Braga, Marianna M. Furtado, Jeany Delafiori, Flavia L. Dias-Audibert, Giuliano E. Pereira, Felix G. Reyes, Rodrigo R. Catharino, Anderson S. Sant'Ana
Article
Environmental Sciences
Thamires Martins, Claudia Schinke, Sonia C. N. Queiroz, Patricia A. de C. Braga, Fabio S. P. Silva, Itamar S. Melo, Felix G. R. Reyes
Summary: The fungus Acremonium camptosporum associated with the marine sponge Aplysina fulva was found to produce antibacterial secondary metabolites. Analysis of mass spectra data revealed the presence of cytotoxic compounds, indicating a close association between the sponge and the fungus with its compounds.
Article
Chemistry, Applied
Ana Paula Ferreira de Souza, Nadia Regina Rodrigues, Felix Guillermo Reyes Reyes
Summary: The study found residues of glyphosate and aminomethylphosphonic acid (AMPA) in Brazilian honey, with some samples showing glyphosate levels exceeding the EU maximum residue limit. This indicates a potential impact on bee populations in regions with high losses of bee colonies and frequent use of glyphosate in agriculture.
FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
(2021)
Article
Veterinary Sciences
Karina P. D. Bonassa, Miwa Y. Miragliotta, Rosineide C. Simas, Marcos N. Eberlin, Arturo Anadon, Ronilson A. Moreno, Felix G. R. Reyes
Summary: Pharmacokinetic parameters and efficacy prediction indexes were determined for an enrofloxacin hydrochloride veterinary product in healthy broiler chickens, showing a success rate of 100% for certain bacterial infections. Clinical trials are needed for confirmation.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Fisheries
Patricia Tidori Miura, Sonia Claudia Nascimento Queiroz, Claudio Martin Jonsson, Edsandra Campos Chagas, Francisco Celio Maia Chaves, Felix Guillermo Reyes
Summary: This study assessed the acute toxicity of seven essential oils on Daphnia magna, finding a range from moderately toxic to slightly toxic. The research suggests that caution should be taken when using these substances in aquaculture, as they may interfere with nontarget organisms.
AQUACULTURE RESEARCH
(2021)
Article
Food Science & Technology
Andrea Renata Bortolotte, Daniela Daniel, Felix Guillermo Reyes Reyes
Summary: This study validated an LC-MS/MS method to detect residues of 25 antimicrobial drugs in tilapia fillet samples from Brazil, identifying residues of oxytetracycline, florfenicol, and enrofloxacin. The findings highlight the need for attention to the use of veterinary products in fish farming in Brazil.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Agriculture, Multidisciplinary
Kemilla S. Rebelo, Cinthia B. B. Cazarin, Amadeu H. Iglesias, Marcella A. Stahl, Karsten Kristiansen, Gislene A. Carvalho-Zilse, Renato Grimaldi, Felix G. R. Reyes, Niels B. Danneskiold-Samsoe, Mario R. M. Junior
Summary: This study provides a comprehensive chemical characterization of M. seminigra pot-pollen for the first time. The samples exhibited antioxidant activity, high nutritional value, and bioactive compounds such as polyphenols, carotenoids, insoluble dietary fibers, polyunsaturated fatty acids, and essential amino acids, comparable to other health foods.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Agronomy
Patricia Tidori Miura, Claudio Martin Jonsson, Sonia Claudia do Nascimento de Queiroz, Edsandra Campos Chagas, Francisco Celio Maia Chaves, Felix Guillermo Reyes Reyes
Summary: The study evaluated the ecotoxicity of Piper aduncum essential oil to five test organisms and determined that it can be safely used in water bodies at a concentration equal to or below 0.09 mg L-1.
Editorial Material
Chemistry, Analytical
Susanne Rath
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Vinicius Diniz, Davi Gasparini Fernandes Cunha, Susanne Rath
Summary: According to the World Health Organization, water quality indicators and contaminants of emerging concern are crucial for the development of wastewater treatment methods for direct potable reuse of water. This study quantified twelve contaminants in a Brazilian wastewater treatment plant and evaluated their adsorption potential onto activated carbon. The researchers also investigated the removal of these contaminants by a multi-barrier system. The results showed promising results for direct potable reuse of water.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Chemistry, Applied
Lucas Victor Pereira de Freitas, Ana Luisa Bigliassi Alponti, Marina Alves Damaceno, Sarah Chagas Campanharo, Agnaldo Fernando Baldo da Silva, James Jacob Sasanya, Susanne Rath, Jonas Augusto Rizzato Paschoal
Summary: This study aimed to evaluate potential procedures for levamisole incorporation in extruded fish feed using different coating agents. The results showed that the ethyl cellulose coating method had the lowest leaching rate, indicating its potential as a promising procedure for levamisole incorporation in fish feed to reduce environmental contamination.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2023)
Article
Toxicology
Vinicius Diniz, Gabriela Rath, Susanne Rath, Caio Rodrigues-Silva, Jose R. Guimaraes, Davi G. F. Cunha
Summary: Ciprofloxacin (CIP) is an antimicrobial compound that can have long-term effects on aquatic ecosystems and microalgae. When combined with caffeine (CAF), the toxic effects on the microalga Raphidocelis subcapitata were alleviated, but the toxicity changed over the exposure period, highlighting the need for longer-term ecotoxicity assessments.
TOXICOLOGY REPORTS
(2021)
Article
Food Science & Technology
Debora Tamires Vitor Pereira, Giovani Leone Zabot, Felix Guillermo Reyes, Amadeu Hoshi Iglesias, Julian Martinez
Summary: This study successfully intensified the recovery of phenolic compounds from passion fruit rinds by combining Pressurized Liquid Extraction and Ultrasound-Assisted Pressurized Liquid Extraction techniques. Optimal process parameters were crucial in maximizing the yield of target compounds, reducing costs, and enhancing product added value.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2021)
Article
Food Science & Technology
Ana Paula Ferreirade Souza, Mateus Henrique Petrarca, Patricia Aparecida de Campos Braga, Nadia Regina Rodrigues, Felix Guillermo Reyes Reyes
Summary: An analytical method using UHPLC-MS/MS and modified QuEChERS sample preparation for detecting insecticide residues in honey was developed and validated. The method showed effective optimization of recovery and reduction in matrix effect using the Plackett Burman design. Insecticide residues were found in 37.3% of the analyzed honey samples, with imidacloprid, clothianidin, and dimethoate being the most frequently detected.
CYTA-JOURNAL OF FOOD
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
