Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53

(2014) Amaya Viros et al.   NATURE

Drugging the p53 pathway: understanding the route to clinical efficacy

(2014) Kian Hoe Khoo et al.   NATURE REVIEWS DRUG DISCOVERY

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

(2014) Jose L. Orgaz et al.   Nature Communications

Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging

(2013) Valentina Gambino et al.   AGING CELL

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

(2013) Min Lu et al.   CANCER CELL

Oxidative stress in melanocyte senescence and melanoma transformation

(2013) Svenja Meierjohann   EUROPEAN JOURNAL OF CELL BIOLOGY

At the leading edge of three-dimensional cell migration

(2013) R. J. Petrie et al.   JOURNAL OF CELL SCIENCE

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of Small GTPases by GEFs, GAPs, and GDIs

(2013) Jacqueline Cherfils et al.   PHYSIOLOGICAL REVIEWS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Phase 1 Clinical Trials of a Selective Rho Kinase Inhibitor, K-115

(2013) Hidenobu Tanihara   JAMA Ophthalmology

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Mitochondrial ROS production under cellular stress: comparison of different detection methods

(2011) Andrey V. Kuznetsov et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

(2011) Victoria Sanz-Moreno et al.   CANCER CELL

PIG3: A novel link between oxidative stress and DNA damage response in cancer

(2011) Athanassios Kotsinas et al.   CANCER LETTERS

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Vitamin E and the Risk of Prostate Cancer

(2011) Eric A. Klein et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells

(2011) A. Lorentzen et al.   JOURNAL OF CELL SCIENCE

p53, Oxidative Stress, and Aging

(2010) Dongping Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Cancer cell killing via ROS: To increase or decrease, that is the question

(2010) Jie Wang et al.   CANCER BIOLOGY & THERAPY

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation

(2010) Tamara Terzian et al.   Pigment Cell & Melanoma Research

Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis

(2010) Blake Ferguson et al.   Pigment Cell & Melanoma Research

Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity

(2009) C. Hahmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3

(2009) Sergio Porté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increasing Burden of Melanoma in the United States

(2009) Eleni Linos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage

(2009) J-H Lee et al.   ONCOGENE

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Trends in prognostic factors and survival from cutaneous melanoma in Yorkshire, UK and New South Wales, Australia between 1993 and 2003

(2008) Amy Downing et al.   INTERNATIONAL JOURNAL OF CANCER

Imaging amoeboid cancer cell motilityin vivo

(2008) S. PINNER et al.   JOURNAL OF MICROSCOPY

Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence

(2008) C Leikam et al.   ONCOGENE