p53, Oxidative Stress, and Aging

Puma is required for p53-induced depletion of adult stem cells

(2010) Dongping Liu et al.   NATURE CELL BIOLOGY

Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer

(2009) Markus Selenius et al.   ANTIOXIDANTS & REDOX SIGNALING

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

(2009) J. N. Bartholomew et al.   CANCER RESEARCH

Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy

(2009) N M Alajez et al.   CELL DEATH AND DIFFERENTIATION

Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes

(2009) Alan R. Collins et al.   CIRCULATION RESEARCH

Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease

(2009) Sandra L. Siedlak et al.   FREE RADICAL RESEARCH

BMP4 Mediates Oxidative Stress-induced Retinal Pigment Epithelial Cell Senescence and Is Overexpressed in Age-related Macular Degeneration

(2009) DanHong Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polycomb Group Gene Bmi1 Regulates Antioxidant Defenses in Neurons by Repressing p53 Pro-Oxidant Activity

(2009) W. Chatoo et al.   JOURNAL OF NEUROSCIENCE

Downregulation of APE1/Ref-1 Is Involved in the Senescence of Mesenchymal Stem Cells

(2009) Jun-Young Heo et al.   STEM CELLS

Bmi1 promotes prostate tumorigenesis via inhibiting p16INK4A and p14ARF expression

(2008) Catherine Fan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

FoxO transcription factors in oxidative stress response and ageing – a new fork on the way to longevity?

(2008) Daniel G. Sedding   BIOLOGICAL CHEMISTRY

Tumor Protein 53-Induced Nuclear Protein 1 Is a Major Mediator of p53 Antioxidant Function

(2008) C. E. Cano et al.   CANCER RESEARCH

Stem Cell Defects in ATM-Deficient Undifferentiated Spermatogonia through DNA Damage-Induced Cell-Cycle Arrest

(2008) Keiyo Takubo et al.   Cell Stem Cell

Zinc, Metallothioneins and Longevity: Interrelationships with Niacin and Selenium

(2008) E. Mocchegiani et al.   CURRENT PHARMACEUTICAL DESIGN

Nonenzymatic posttranslational protein modifications in ageing

(2008) Vukić Šoškić et al.   EXPERIMENTAL GERONTOLOGY

Vitamins E and C in the Prevention of Cardiovascular Disease in Men

(2008) Howard D. Sesso   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of ANKRD11 as a p53 coactivator

(2008) P. M. Neilsen et al.   JOURNAL OF CELL SCIENCE

Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans

(2008) Juewon Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement

(2008) J. A. Lemon et al.   MUTAGENESIS

DNA damage and ageing: new-age ideas for an age-old problem

(2008) George A. Garinis et al.   NATURE CELL BIOLOGY

Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin

(2008) Yoshihiro Dohi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53–induced apoptosis

(2008) Akira Nakamizo et al.   NEURO-ONCOLOGY

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

(2008) A. Zaky et al.   NUCLEIC ACIDS RESEARCH

A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice

(2008) Jamie L. Barger et al.   PLoS One