Molecular chaperones as enzymes that catalytically unfold misfolded polypeptides

Unique Structural Modulation of a Non-Native Substrate by Cochaperone DnaJ

(2013) Satyam Tiwari et al.   BIOCHEMISTRY

Prion-like spreading of pathological α-synuclein in brain

(2013) Masami Masuda-Suzukake et al.   BRAIN

Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis

(2013) Andrija Finka et al.   CELL STRESS & CHAPERONES

Biophysical Characterization of Two Different Stable Misfolded Monomeric Polypeptides That Are Chaperone-Amenable Substrates

(2013) Antonino Natalello et al.   JOURNAL OF MOLECULAR BIOLOGY

GroEL and CCT are catalytic unfoldases mediating out-of-cage polypeptide refolding without ATP

(2013) S. Priya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone–protease networks in mitochondrial protein homeostasis

(2012) Wolfgang Voos   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Metazoan Hsp70 machines use Hsp110 to power protein disaggregation

(2012) Heike Rampelt et al.   EMBO JOURNAL

Concerted Action of the Ribosome and the Associated Chaperone Trigger Factor Confines Nascent Polypeptide Folding

(2012) Anja Hoffmann et al.   MOLECULAR CELL

Prion propagation, toxicity and degradation

(2012) Adriano Aguzzi et al.   NATURE NEUROSCIENCE

E. coli chaperones DnaK, Hsp33 and Spy inhibit bacterial functional amyloid assembly

(2012) Margery L. Evans et al.   Prion

Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases from Yeast and Humans

(2012) Martin L. Duennwald et al.   PLOS BIOLOGY

Amyloidosis

(2012) J. H. Pinney et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Molecular Chaperones and Associated Cellular Clearance Mechanisms against Toxic Protein Conformers in Parkinson’s Disease

(2011) Marie-Pierre Hinault et al.   Neurodegenerative Diseases

The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System

(2011) James Shorter   PLoS One

Probing the different chaperone activities of the bacterial HSP70-HSP40 system using a thermolabile luciferase substrate

(2011) Sandeep K. Sharma et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein import into chloroplasts—How chaperones feature into the game

(2010) Serena Schwenkert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells

(2010) Andrija Finka et al.   CELL STRESS & CHAPERONES

Stable α-Synuclein Oligomers Strongly Inhibit Chaperone Activity of the Hsp70 System by Weak Interactions with J-domain Co-chaperones

(2010) Marie-Pierre Hinault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

A story of thrift unfolds

(2010) François Baneyx et al.   Nature Chemical Biology

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

(2010) Sandeep K Sharma et al.   Nature Chemical Biology

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chaperone networks: Tipping the balance in protein folding diseases

(2010) Cindy Voisine et al.   NEUROBIOLOGY OF DISEASE

Nature's molecular sponges: Small heat shock proteins grow into their chaperone roles

(2010) S. J. Eyles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disaggregating Chaperones: An Unfolding Story

(2009) Sandeep Sharma et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

The eye lens chaperone  -crystallin forms defined globular assemblies

(2009) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Synuclein Misfolding and Neurodegenerative Diseases

(2008) Vladimir Uversky   CURRENT PROTEIN & PEPTIDE SCIENCE

GroEL stimulates protein folding through forced unfolding

(2008) Zong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY