Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

(2013) Karel Smetana et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Single-Site Mutational Engineering and Following MonoPEGylation of the Human Lectin Galectin-2: Effects on Ligand Binding, Functional Aspects, and Clearance from Serum

(2013) Jürgen Kopitz et al.   MOLECULAR PHARMACEUTICS

Pitfalls of predicting complex traits from SNPs

(2013) Naomi R. Wray et al.   NATURE REVIEWS GENETICS

Sterical Hindrance Promotes Selectivity of the Autophagy Cargo Receptor NDP52 for the Danger Receptor Galectin-8 in Antibacterial Autophagy

(2013) S. Li et al.   Science Signaling

Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8

(2013) Byeong-Won Kim et al.   Nature Communications

T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival

(2012) Mary C. Clark et al.   Annals of the New York Academy of Sciences

Galectins in acute and chronic inflammation

(2012) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: Association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population

(2012) Zsuzsanna Pál et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains

(2012) Hiromi Yoshida et al.   FEBS Journal

Tumour suppressor p16INK4a- anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model

(2012) Maho Amano et al.   FEBS Journal

Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus

(2012) K. Sarter et al.   GLYCOBIOLOGY

Comparative study of the glycan specificities of cell-bound human tandem-repeat-type galectin-4, -8 and -9

(2012) Olga A Vokhmyanina et al.   GLYCOBIOLOGY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Ganglioside GM1/Galectin-Dependent Growth Regulation in Human Neuroblastoma Cells: Special Properties of Bivalent Galectin-4 and Significance of Linker Length for Ligand Selection

(2012) Jürgen Kopitz et al.   NEUROCHEMICAL RESEARCH

The effect of galectin-3 genetic variants on the susceptibility and prognosis of gliomas in a Chinese population

(2012) Hong-jie Chen et al.   NEUROSCIENCE LETTERS

Galectin-3 genetic variants are associated with platinum-based chemotherapy response and prognosis in patients with NSCLC

(2012) Fenglei Wu et al.   CELLULAR ONCOLOGY

Galectin-8 tandem-repeat structure is essential for T-cell proliferation but not for co-stimulation

(2011) Valentina Cattaneo et al.   BIOCHEMICAL JOURNAL

Carbohydrate specificity of chicken and human tandem-repeat-type galectins-8 in composition of cells

(2011) O. A. Vokhmyanina et al.   BIOCHEMISTRY-MOSCOW

A galectin-3 sequence polymorphism confers TRAIL sensitivity to human breast cancer cells

(2011) Nachman Mazurek et al.   CANCER

Galectin-3 gene (LGALS3) +292C allele is a genetic predisposition factor for rheumatoid arthritis in Taiwan

(2011) Chung-Yi Hu et al.   CLINICAL RHEUMATOLOGY

Ganglioside GM1 Deficiency in Effector T Cells From NOD Mice Induces Resistance to Regulatory T-Cell Suppression

(2011) G. Wu et al.   DIABETES

Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential

(2011) Myriam Remmelink et al.   HISTOPATHOLOGY

Galectin-8-N-domain Recognition Mechanism for Sialylated and Sulfated Glycans

(2011) Hiroko Ideo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-1 and Galectin-8 Have Redundant Roles in Promoting Plasma Cell Formation

(2011) C.-M. Tsai et al.   JOURNAL OF IMMUNOLOGY

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Apoptosis gene polymorphisms and risk of prostate cancer: A hospital-based study of German patients treated with brachytherapy

(2011) Andreas Meyer et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Hydrodynamic Properties of Human Adhesion/Growth-Regulatory Galectins Studied by Fluorescence Correlation Spectroscopy

(2010) Antonia Göhler et al.   BIOPHYSICAL JOURNAL

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

A Novel Function of Siglec-9 A391C Polymorphism on T Cell Receptor Signaling

(2010) Kyung Ah Cheong et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

N-domain of human adhesion/growth-regulatory galectin-9: Preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution

(2010) Dolores Solís et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: Case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

(2010) Jürgen Kopitz et al.   IUBMB LIFE

A novel galectin-1 and interleukin 2 receptor β haplotype is associated with autoimmune myasthenia gravis

(2010) Zsuzsanna Pál et al.   JOURNAL OF NEUROIMMUNOLOGY

Lack of association between lymphotoxin-α, galectin-2 polymorphisms and coronary artery disease: A meta-analysis

(2009) Wenlong Li et al.   ATHEROSCLEROSIS

Unique Chicken Tandem-Repeat-Type Galectin: Implications of Alternative Splicing and a Distinct Expression Profile Compared to Those of the Three Proto-Type Proteins

(2009) Herbert Kaltner et al.   BIOCHEMISTRY

Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

(2009) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Galectin-8 provides costimulatory and proliferative signals to T lymphocytes

(2009) María Virginia Tribulatti et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation

(2009) L Massardo et al.   LUPUS

MBL2, FCN1, FCN2 and FCN3—The genes behind the initiation of the lectin pathway of complement

(2009) Peter Garred et al.   MOLECULAR IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals

(2008) Herbert Kaltner et al.   BIOCHEMICAL JOURNAL

Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study

(2008) V. Balan et al.   CANCER RESEARCH

Dimeric Galectin-8 Induces Phosphatidylserine Exposure in Leukocytes through Polylactosamine Recognition by the C-terminal Domain

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY