Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1

Signals regulating necrosis of cardiomyoblast by BTG2/TIS21/PC3 via activation of GSK3β and opening of mitochondrial permeability transition pore in response to H2O2

(2013) Yong Won Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients

(2013) N Wagener et al.   BRITISH JOURNAL OF CANCER

B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells

(2013) Santhoshkumar Sundaramoorthy et al.   Cell Communication and Signaling

Regulation of Btg2/TIS21/PC3 expression via reactive oxygen species–protein kinase C–ΝFκΒ pathway under stress conditions

(2013) Muhammad Imran et al.   CELLULAR SIGNALLING

TIS21/BTG2 inhibits invadopodia formation by downregulating reactive oxygen species level in MDA-MB-231 cells

(2013) Jung-A. Choi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Hepatitis C virus core protein epigenetically silences SFRP1 and enhances HCC aggressiveness by inducing epithelial–mesenchymal transition

(2013) H Quan et al.   ONCOGENE

Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival

(2012) Yan-Wei Tan et al.   BMC NEUROSCIENCE

BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

(2012) Seo-Kyung Lim et al.   CLINICAL & EXPERIMENTAL METASTASIS

ICUD-EAU International Consultation on Bladder Cancer 2012: Pathology

(2012) Mahul B. Amin et al.   EUROPEAN UROLOGY

Tis21 Knock-Out Enhances the Frequency of Medulloblastoma in Patched1 Heterozygous Mice by Inhibiting the Cxcl3-Dependent Migration of Cerebellar Neurons

(2012) S. Farioli-Vecchioli et al.   JOURNAL OF NEUROSCIENCE

Demethylation of the Coding Region Triggers the Activation of the Human Testis-Specific PDHA2 Gene in Somatic Tissues

(2012) Ana Pinheiro et al.   PLoS One

The Anti-Proliferative Activity of BTG/TOB Proteins Is Mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) Deadenylase Subunits of the Ccr4-Not Complex

(2012) Rachel Doidge et al.   PLoS One

Hydrogen peroxide induces Sp1 methylation and thereby suppresses cyclin B1 via recruitment of Suv39H1 and HDAC1 in cancer cells

(2011) Jian-Ying Chuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multiplexed Methylation Profiles of Tumor Suppressor Genes in Bladder Cancer

(2011) Maria José Cabello et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib

(2011) F Takahashi et al.   ONCOGENE

Overexpression of DNA Methyltransferases 1, 3a, and 3b Significantly Correlates With Retinoblastoma Tumorigenesis

(2010) Yi Qu et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Targeting DNA Methylation

(2009) J.-P. J. Issa et al.   CLINICAL CANCER RESEARCH

Molecular Pathogenesis and Diagnostics of Bladder Cancer

(2008) Anirban P. Mitra et al.   Annual Review of Pathology-Mechanisms of Disease

Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

(2008) M. Toyota et al.   CANCER RESEARCH

The BTG2 protein is a general activator of mRNA deadenylation

(2008) Fabienne Mauxion et al.   EMBO JOURNAL

TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop

(2008) Tae Jun Park et al.   HEPATOLOGY

Estradiol downregulation of the tumor suppressor geneBTG2requires estrogen receptor-α and the REA corepressor

(2008) Sudipan Karmakar et al.   INTERNATIONAL JOURNAL OF CANCER