ATP binding to human serine racemase is cooperative and modulated by glycine

Allostery in Disease and in Drug Discovery

(2013) Ruth Nussinov et al.   CELL

Serine racemase as a prime target for age-related memory deficits

(2013) J.-M. Billard   EUROPEAN JOURNAL OF NEUROSCIENCE

Serine racemase: a key player in neuron activity and in neuropathologies

(2013) Andrea Mozzarelli   Frontiers in Bioscience-Landmark

Neuronal D-Serine and Glycine Release Via the Asc-1 Transporter Regulates NMDA Receptor-Dependent Synaptic Activity

(2013) D. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Activation: Two Targets for Two Co-Agonists

(2013) Christian Henneberger et al.   NEUROCHEMICAL RESEARCH

Catalytic mechanism of serine racemase from Dictyostelium discoideum

(2012) Tomokazu Ito et al.   AMINO ACIDS

Serine racemase: an unconventional enzyme for an unconventional transmitter

(2012) Herman Wolosker et al.   AMINO ACIDS

Structure–function relationships in human d-amino acid oxidase

(2012) Silvia Sacchi et al.   AMINO ACIDS

Allostery and the Monod-Wyman-Changeux Model After 50 Years

(2012) Jean-Pierre Changeux   Annual Review of Biophysics

Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase

(2012) Francesca Spyrakis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons

(2012) Michael A. Benneyworth et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion

(2012) T M Ma et al.   MOLECULAR PSYCHIATRY

Serine racemase and the serine shuttle between neurons and astrocytes

(2011) Herman Wolosker   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Drug Discovery Targeting Amino Acid Racemases

(2011) Paola Conti et al.   CHEMICAL REVIEWS

Inhibition of Human Serine Racemase, an Emerging Target for Medicinal Chemistry

(2011) Jana Jiraskova-Vanickova et al.   CURRENT DRUG TARGETS

Human kynurenine aminotransferase II - reactivity with substrates and inhibitors

(2011) Elisabetta Passera et al.   FEBS Journal

Measurement of glycine in the human brain in vivo by 1H-MRS at 3 T: application in brain tumors

(2011) Changho Choi et al.   MAGNETIC RESONANCE IN MEDICINE

Levels of d-serine in the brain and peripheral organs of serine racemase (Srr) knock-out mice

(2011) Mao Horio et al.   NEUROCHEMISTRY INTERNATIONAL

Contributions of the d-serine pathway to schizophrenia

(2011) Viviane Labrie et al.   NEUROPHARMACOLOGY

Exploring and exploiting allostery: Models, evolution, and drug targeting

(2010) Alessio Peracchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Metabolism of the neuromodulator d-serine

(2010) Loredano Pollegioni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phosphorylation of mouse serine racemase regulatesd-serine synthesis

(2010) Veronika N. Foltyn et al.   FEBS LETTERS

The Structure of Mammalian Serine Racemase

(2010) Myron A. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Two-step Process Controls the Formation of the Bienzyme Cysteine Synthase Complex

(2010) Enea Salsi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serine Racemase Deletion Protects Against Cerebral Ischemia and Excitotoxicity

(2010) A. K. Mustafa et al.   JOURNAL OF NEUROSCIENCE

Localization of d-serine and serine racemase in neurons and neuroglias in mouse brain

(2010) Xiaohui Ding et al.   NEUROLOGICAL SCIENCES

Crystal Structure of a Homolog of Mammalian Serine Racemase fromSchizosaccharomyces pombe

(2009) Masaru Goto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design ofO-Acetylserine Sulfhydrylase Inhibitors by Mimicking Nature

(2009) Enea Salsi et al.   JOURNAL OF MEDICINAL CHEMISTRY

d-Amino acids in the brain: d-serine in neurotransmission and neurodegeneration

(2008) Herman Wolosker et al.   FEBS Journal

d-Amino acids in the brain: structure and function of pyridoxal phosphate-dependent amino acid racemases

(2008) Tohru Yoshimura et al.   FEBS Journal

Recombinant human serine racemase: Enzymologic characterization and comparison with its mouse ortholog

(2008) Hillary E. Hoffman et al.   PROTEIN EXPRESSION AND PURIFICATION

Allostery and cooperativity revisited

(2008) Qiang Cui et al.   PROTEIN SCIENCE

High and low oxygen affinity conformations of T state hemoglobin

(2002) Stefano Bruno et al.   PROTEIN SCIENCE