Molecular mechanisms of the PRL phosphatases

The essential role of FKBP38 in regulating phosphatase of regenerating liver 3 (PRL-3) protein stability

(2011) Myung-Suk Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Metastasis-Promoting Phosphatase PRL-3 Shows Activity toward Phosphoinositides

(2011) Victoria McParland et al.   BIOCHEMISTRY

Snail as a key regulator of PRL-3 gene in colorectal cancer

(2011) Ping Zheng et al.   CANCER BIOLOGY & THERAPY

Ezrin, Radixin and Moesin: key regulators of membrane–cortex interactions and signaling

(2011) Amanda L Neisch et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphatase of regenerating liver-3 promotes migration and invasion by upregulating matrix metalloproteinases-7 in human colorectal cancer cells

(2011) Su-Kyung Lee et al.   INTERNATIONAL JOURNAL OF CANCER

PRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating Protein

(2011) Yunpeng Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Cytoplasmic Phosphatase and Tensin Homolog (PTEN)-like Region ofCiona intestinalisVoltage-sensing Phosphatase Provides Insight into Substrate Specificity and Redox Regulation of the Phosphoinositide Phosphatase Activity

(2011) Makoto Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BCL-2 Is a Downstream Target of ATF5 That Mediates the Prosurvival Function of ATF5 in a Cell Type-dependent Manner

(2011) Douglas Dluzen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion

(2011) Y Wang et al.   ONCOGENE

Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment

(2011) L Heiska et al.   ONCOGENE

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

(2011) Jianbiao Zhou et al.   PLoS One

VEGF Promotes the Transcription of the Human PRL-3 Gene in HUVEC through Transcription Factor MEF2C

(2011) Jianliang Xu et al.   PLoS One

Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis

(2011) J. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

(2010) A. Broyl et al.   BLOOD

PRL-2 increases Epo and IL-3 responses in hematopoietic cells

(2010) Shoko Akiyama et al.   BLOOD CELLS MOLECULES AND DISEASES

Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice

(2010) Ke Guo et al.   CANCER BIOLOGY & THERAPY

PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly

(2010) Yuhong Liu et al.   CANCER BIOLOGY & THERAPY

PCBP1 Suppresses the Translation of Metastasis-Associated PRL-3 Phosphatase

(2010) Haihe Wang et al.   CANCER CELL

Overexpression of the Protein Tyrosine Phosphatase PRL-2 Correlates with Breast Tumor Formation and Progression

(2010) S. Hardy et al.   CANCER RESEARCH

Phosphatase PRL-3 Is a Direct Regulatory Target of TGF  in Colon Cancer Metastasis

(2010) Y. Jiang et al.   CANCER RESEARCH

Requirement of phosphatase of regenerating liver-3 for the nucleolar localization of nucleolin during the progression of colorectal carcinoma

(2010) Shuho Semba et al.   CANCER SCIENCE

PRL-3 phosphatase and cancer metastasis

(2010) Abdul Qader O. Al-Aidaroos et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phosphatase of Regenerating Liver-1 Promotes Cell Migration and Invasion and Regulates Filamentous Actin Dynamics

(2010) M. Nakashima et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Stathmin, a New Target of PRL-3 Identified by Proteomic Methods, Plays a Key Role in Progression and Metastasis of Colorectal Cancer

(2010) Ping Zheng et al.   JOURNAL OF PROTEOME RESEARCH

Expression of phosphatase of regenerating liver-3 in squamous cell carcinoma of the cervix

(2010) Yaxi Ma et al.   MEDICAL ONCOLOGY

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

(2009) Lisa M. Ooms et al.   BIOCHEMICAL JOURNAL

PRL1 Promotes Cell Migration and Invasion by Increasing MMP2 and MMP9 Expression through Src and ERK1/2 Pathways†

(2009) Yong Luo et al.   BIOCHEMISTRY

Enzyme Activity of Phosphatase of Regenerating Liver Is Controlled by the Redox Environment and Its C-Terminal Residues

(2009) Andria L. Skinner et al.   BIOCHEMISTRY

2-D Difference in gel electrophoresis combined with Pro-Q Diamond staining: A successful approach for the identification of kinase/phosphatase targets

(2009) Laura Orsatti et al.   ELECTROPHORESIS

Downregulation of p53 by phosphatase of regenerating liver 3 is mediated by MDM2 and PIRH2

(2009) Sang-Hyun Min et al.   LIFE SCIENCES

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

(2009) Lirong Peng et al.   Molecular Cancer

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

PRL-3 facilitates angiogenesis and metastasis by increasing ERK phosphorylation and up-regulating the levels and activities of Rho-A/C in lung cancer

(2009) Jian Ming et al.   PATHOLOGY

Mass spectrometry study of PRL-3 phosphatase inactivation by disulfide bond formation and cysteine into glycine conversion

(2009) Laura Orsatti et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

PRL PTPs: mediators and markers of cancer progression

(2008) Darrell C. Bessette et al.   CANCER AND METASTASIS REVIEWS

A Selective Phosphatase of Regenerating Liver Phosphatase Inhibitor Suppresses Tumor Cell Anchorage-Independent Growth by a Novel Mechanism Involving p130Cas Cleavage

(2008) S. Daouti et al.   CANCER RESEARCH

Down-modulation of keratin 8 phosphorylation levels by PRL-3 contributes to colorectal carcinoma progression

(2008) Eri Mizuuchi et al.   INTERNATIONAL JOURNAL OF CANCER

Translational Control of C-terminal Src Kinase (Csk) Expression by PRL3 Phosphatase

(2008) Fubo Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of molecular determinants of PRL-3

(2008) Mihaela Pascaru et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells

(2008) B. Stephens et al.   MOLECULAR CANCER THERAPEUTICS

The Metastasis-Associated Gene Prl-3 Is a p53 Target Involved in Cell-Cycle Regulation

(2008) Shashwati Basak et al.   MOLECULAR CELL

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53

(2008) S-H Min et al.   ONCOGENE

A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate

(2008) H. Iwasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ezrin is a specific and direct target of protein tyrosine phosphatase PRL-3

(2007) Eleonora Forte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells

(2007) U.-M. Fagerli et al.   BLOOD