Conclusions via unique predictions obtained despite unidentifiability - new definitions and a general method

An integrated strategy for prediction uncertainty analysis

(2012) J. Vanlier et al.   BIOINFORMATICS

Mechanistic explanations for counter-intuitive phosphorylation dynamics of the insulin receptor and insulin receptor substrate-1 in response to insulin in murine adipocytes

(2012) Elin Nyman et al.   FEBS Journal

Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: application to systems biology models

(2012) Maria Rodriguez-Fernandez et al.   INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL

A method for zooming of nonlinear models of biochemical systems

(2011) Mikael Sunnåker et al.   BMC Systems Biology

Identifiability and observability analysis for experimental design in nonlinear dynamical models

(2011) A. Raue et al.   CHAOS

Addressing parameter identifiability by model-based experimentation

(2011) A. Raue et al.   IET Systems Biology

Sensitivity analysis approaches applied to systems biology models

(2011) Z. Zi   IET Systems Biology

A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis

(2011) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Workflow for generating competing hypothesis from models with parameter uncertainty

(2011) D. Gomez-Cabrero et al.   Interface Focus

Zooming of states and parameters using a lumping approach including back-translation

(2010) Mikael Sunnaker et al.   BMC Systems Biology

Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effects

(2010) Jacqueline M Dresch et al.   BMC Systems Biology

Model-based inference of biochemical parameters and dynamic properties of microbial signal transduction networks

(2010) Jörg Schaber et al.   CURRENT OPINION IN BIOTECHNOLOGY

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

(2010) Tim Maiwald et al.   FEBS Journal

Parameter identification, experimental design and model falsification for biological network models using semidefinite programming

(2010) J. Hasenauer et al.   IET Systems Biology

Cellular modeling: insight into oral minimal models of insulin secretion

(2009) Morten Gram Pedersen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

Computational disease modeling – fact or fiction?

(2009) Jesper N Tegnér et al.   BMC Systems Biology

Systems biology: model based evaluation and comparison of potential explanations for given biological data

(2009) Gunnar Cedersund et al.   FEBS Journal

A new strategy for assessing sensitivities in biochemical models

(2008) S. Sahle et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES