Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology

Multidimensional Structure-Activity Relationship of a Protein in Its Aggregated States

(2010) Lei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Enzyme Immobilization by Inclusion Body Display

(2010) B. Steinmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Activity of maize transglutaminase overexpressed in escherichia coli inclusion bodies: An alternative to protein refolding

(2010) Patricia Carvajal et al.   BIOTECHNOLOGY PROGRESS

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

Protein folding in the cell: challenges and progress

(2010) Anne Gershenson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing

(2010) Juliane Winkler et al.   EMBO JOURNAL

Proteome-Level Interplay between Folding and Aggregation Propensities of Proteins

(2010) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

Tunable geometry of bacterial inclusion bodies as substrate materials for tissue engineering

(2010) Elena García-Fruitós et al.   NANOTECHNOLOGY

A story of thrift unfolds

(2010) François Baneyx et al.   Nature Chemical Biology

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers

(2010) Luisa Diomede et al.   NEUROBIOLOGY OF DISEASE

Protein Aggregation Profile of the Bacterial Cytosol

(2010) Natalia S. de Groot et al.   PLoS One

Crowding and hydrodynamic interactions likely dominate in vivo macromolecular motion

(2010) T. Ando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translationally optimal codons associate with aggregation-prone sites in proteins

(2010) Yaelim Lee et al.   PROTEOMICS

Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm

(2010) Sean R. McGuffee et al.   PLoS Computational Biology

Solid-State NMR Spectroscopy Reveals thatE. coliInclusion Bodies of HET-s(218-289) are Amyloids

(2009) Christian Wasmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carrier-free immobilized enzymes for biocatalysis

(2009) Ulrich Roessl et al.   BIOTECHNOLOGY LETTERS

Stress responses to heterologous membrane protein expression in Escherichia coli

(2009) Lucy Y. Xu et al.   BIOTECHNOLOGY LETTERS

Stability effects of mutations and protein evolvability

(2009) Nobuhiko Tokuriki et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

E. coli Transports Aggregated Proteins to the Poles by a Specific and Energy-Dependent Process

(2009) Assaf Rokney et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion

(2009) Raimon Sabaté et al.   Microbial Cell Factories

Components of the E. coli envelope are affected by and can react to protein over-production in the cytoplasm

(2009) Riccardo Villa et al.   Microbial Cell Factories

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

(2009) Günter Kramer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enzymatic synthesis of sialylation substrates powered by a novel polyphosphate kinase (PPK3)

(2009) Jozef Nahálka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

(p)ppGpp: Still Magical?

(2008) Katarzyna Potrykus et al.   Annual Review of Microbiology

Inclusion bodies: Specificity in their aggregation process and amyloid-like structure

(2008) Montse Morell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of recombinant protein misfolding and aggregation on bacterial membranes

(2008) D. Ami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Fourier transform infrared spectroscopy analysis of the conformational quality of recombinant proteins within inclusion bodies

(2008) Silvia Maria Doglia et al.   Biotechnology Journal

Impact of different cultivation and induction regimes on the structure of cytosolic inclusion bodies of TEM1-β-lactamase

(2008) Gerd Margreiter et al.   Biotechnology Journal

Protein Aggregates: an Aging Factor Involved in Cell Death

(2008) E. Maisonneuve et al.   JOURNAL OF BACTERIOLOGY

A crosslinked inclusion body process for sialic acid synthesis

(2008) Jozef Nahálka et al.   JOURNAL OF BIOTECHNOLOGY

Monitoring of transcriptome and proteome profiles to investigate the cellular response of E. coli towards recombinant protein expression under defined chemostat conditions

(2008) Karin Dürrschmid et al.   JOURNAL OF BIOTECHNOLOGY

Native Conformation at Specific Residues in Recombinant Inclusion Body Protein in Whole Cells Determined with Solid-State NMR Spectroscopy

(2008) Jaime Curtis-Fisk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering inclusion bodies for non denaturing extraction of functional proteins

(2008) Špela Peternel et al.   Microbial Cell Factories

Convergence of Molecular, Modeling, and Systems Approaches for an Understanding of the Escherichia coli Heat Shock Response

(2008) E. Guisbert et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Atomic force microscopy as a multifunctional molecular toolbox in nanobiotechnology

(2008) Daniel J. Müller et al.   Nature Nanotechnology

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

(2008) A. B. Lindner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo aggregation of bovine β-lactoglobulin is affected by Cys at position 121

(2008) Gaetano Invernizzi et al.   PROTEIN EXPRESSION AND PURIFICATION

Bacterial Inclusion Bodies Contain Amyloid-Like Structure

(2008) Lei Wang et al.   PLOS BIOLOGY

Production of Nonclassical Inclusion Bodies from Which Correctly Folded Protein Can Be Extracted

(2005) Simona Jevševar et al.   BIOTECHNOLOGY PROGRESS