The lectin-like oxidized low-density lipoprotein receptor-1 as therapeutic target for atherosclerosis, inflammatory conditions and longevity

Lipoprotein apheresis of hypercholesterolemic patients mediates vasoprotective gene expression in human endothelial cells

(2013) Henning Morawietz et al.   ATHEROSCLEROSIS SUPPLEMENTS

Current Concepts of the Role of Oxidized LDL Receptors in Atherosclerosis

(2012) Tanu Goyal et al.   Current Atherosclerosis Reports

LOX-1

(2012) Tatsuya Sawamura et al.   CURRENT OPINION IN LIPIDOLOGY

SIRT1 – An Anti-Inflammatory Pathway at the Crossroads Between Metabolic Disease and Atherosclerosis

(2012) Stephan Winnik et al.   Current Vascular Pharmacology

Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride

(2012) Jia-Xiao Zhu et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Berberine-induced inhibition of adipocyte enhancer-binding protein 1 attenuates oxidized low-density lipoprotein accumulation and foam cell formation in phorbol 12-myristate 13-acetate-induced macrophages

(2012) Zhouqing Huang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNA hsa-let-7g targets lectin-like oxidized low-density lipoprotein receptor-1 expression and inhibits apoptosis in human smooth muscle cells

(2012) Zufeng Ding et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Comparative Binding Effects of Aspirin and Anti-Inflammatory Cu Complex in the Active Site of LOX-1

(2012) E. Vrontaki et al.   Journal of Chemical Information and Modeling

Circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels predict percutaneous coronary intervention-related periprocedural myocardial infarction in stable patients undergoing elective native single-vessel PCI

(2012) Mehmet Balin et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity

(2012) Dongmei Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Novel neurological and immunological targets for salicylate-based phytopharmaceuticals and for the anti-depressant imipramine

(2012) G. Ulrich-Merzenich et al.   PHYTOMEDICINE

Ginkgo biloba extract and Aspirin synergistically attenuate activated platelet-induced ROS production and LOX-1 expression in human coronary artery endothelial cells

(2012) Xianguan Zhu et al.   PHYTOMEDICINE

Association between OLR1 K167N SNP and Intima Media Thickness of the Common Carotid Artery in the General Population

(2012) Irene Marta Predazzi et al.   PLoS One

Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation

(2012) Suowen Xu et al.   Translational Research

LOX-1 Inhibition in ApoE KO Mice Using a Schizophyllan-based Antisense Oligonucleotide Therapy

(2012) Francesca Amati et al.   Molecular Therapy-Nucleic Acids

Lectin-like oxidized low-density lipoprotein receptor 1 signal is a potent biomarker and therapeutic target for human rheumatoid arthritis

(2011) Masahiro Ishikawa et al.   ARTHRITIS AND RHEUMATISM

The Discovery of LOX-1, its Ligands and Clinical Significance

(2011) Ryo Yoshimoto et al.   CARDIOVASCULAR DRUGS AND THERAPY

Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Associated With Angiographic Coronary Lesion Complexity in Patients With Coronary Artery Disease

(2011) Zi-Wen Zhao et al.   CLINICAL CARDIOLOGY

Circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are associated with proximal/middle segment of the LAD lesions in patients with stable coronary artery disease

(2011) Mehmet Balın et al.   Clinical Research in Cardiology

Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels

(2011) Kimberly A. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1

(2011) K.-C. Chen et al.   JOURNAL OF CELL SCIENCE

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

(2011) Christian Besler et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunoliposomal drug-delivery system targeting lectin-like oxidized low-density lipoprotein receptor–1 for carotid plaque lesions in rats

(2011) Atsushi Saito et al.   JOURNAL OF NEUROSURGERY

Chlamydia pneumoniae binds to the lectin-like oxidized LDL receptor for infection of endothelial cells

(2011) Lee Ann Campbell et al.   MICROBES AND INFECTION

Oxidized LDL Receptor 1 (OLR1) as a Possible Link between Obesity, Dyslipidemia and Cancer

(2011) Magomed Khaidakov et al.   PLoS One

Procyanidins are potent inhibitors of LOX-1: a new player in the French Paradox

(2011) Taichi NISHIZUKA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Preparation and Enhanced Oral Bioavailability of Cryptotanshinone-Loaded Solid Lipid Nanoparticles

(2010) LianDong Hu et al.   AAPS PHARMSCITECH

OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

(2010) Sungwoo Ryoo et al.   ATHEROSCLEROSIS

Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Predicts Prognosis After Acute Coronary Syndrome

(2010) Noriaki Kume et al.   CIRCULATION JOURNAL

Der LOX-1-Rezeptor als neues Zielmolekül bei endothelialer Dysfunktion und Atherosklerose

(2010) H Morawietz   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome—Comparison with other biomarkers

(2010) Noriaki Kume et al.   Journal of Cardiology

Curcumin Reduces Angiotensin II–mediated Cardiomyocyte Growth via LOX-1 Inhibition

(2010) Bum-Yong Kang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Resveratrol Attenuates Oxidized LDL-Evoked Lox-1 Signaling and Consequently Protects against Apoptotic Insults to Cerebrovascular Endothelial Cells

(2010) Huai-Chia Chang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Delivers Heat Shock Protein 60-Fused Antigen into the MHC Class I Presentation Pathway

(2010) J. Xie et al.   JOURNAL OF IMMUNOLOGY

Apigenin inhibits tumor necrosis factor alpha plus high glucose-induced LOX-1 expression in human endothelial cells

(2010) Kazuo Yamagata et al.   MICROVASCULAR RESEARCH

Scavenger Receptors of Endothelial Cells Mediate the Uptake and Cellular Proatherogenic Effects of Carbamylated LDL

(2009) Eugene O. Apostolov et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet

(2009) Birgit Eichhorn et al.   CARDIOVASCULAR RESEARCH

LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

(2009) Koichi Sugimoto et al.   CARDIOVASCULAR RESEARCH

Mediation of Electronegative Low-Density Lipoprotein Signaling by LOX-1

(2009) Jonathan Lu et al.   CIRCULATION RESEARCH

Oligomerization is required for the activity of recombinant soluble LOX-1

(2009) Wei Cao et al.   FEBS Journal

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+signaling pathways in endothelial cells

(2009) Nobuo Sakamoto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A novel gene silencer, pyrrole–imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function

(2009) Takahiro Ueno et al.   JOURNAL OF HYPERTENSION

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1

(2009) Qiaohua Kang et al.   LABORATORY INVESTIGATION

Functional Analysis and Molecular Dynamics Simulation of LOX-1 K167N Polymorphism Reveal Alteration of Receptor Activity

(2009) Silvia Biocca et al.   PLoS One

A Developmental Model of Sarcomagenesis Defines a Differentiation-Based Classification for Liposarcomas

(2008) Igor Matushansky et al.   AMERICAN JOURNAL OF PATHOLOGY

LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet

(2008) C. Hu et al.   CARDIOVASCULAR RESEARCH

Oxidized LDL Receptor LOX-1 Binds to C-Reactive Protein and Mediates Its Vascular Effects

(2008) Y. Fujita et al.   CLINICAL CHEMISTRY

Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Attenuates Restenosis of the Artery After Injury

(2008) En-Hui Yao et al.   HYPERTENSION

Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 correlates with oxidative stress markers in stable coronary artery disease

(2008) Fumihiko Kamezaki et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Regulation of TGFβ1-mediated Collagen Formation by LOX-1

(2008) Changping Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The LDL modification hypothesis of atherogenesis: an update

(2008) Daniel Steinberg   JOURNAL OF LIPID RESEARCH

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization

(2008) Silvia Biocca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY