The Discovery of LOX-1, its Ligands and Clinical Significance

Lipid Peroxidation Modification of Protein GeneratesNϵ-(4-Oxononanoyl)lysine as a Pro-inflammatory Ligand

(2011) Takahiro Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Procyanidins are potent inhibitors of LOX-1: a new player in the French Paradox

(2011) Taichi NISHIZUKA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Concept of Vulnerable/Unstable Plaque

(2010) Aloke V. Finn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice

(2010) Rieko Takanabe-Mori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Predicts Prognosis After Acute Coronary Syndrome

(2010) Noriaki Kume et al.   CIRCULATION JOURNAL

C-Reactive Protein Uptake by Macrophage Cell Line via Class-A Scavenger Receptor

(2010) Y. Fujita et al.   CLINICAL CHEMISTRY

LOX Index, a Novel Predictive Biochemical Marker for Coronary Heart Disease and Stroke

(2010) N. Inoue et al.   CLINICAL CHEMISTRY

Lipid Peroxidation Generates Body Odor Componenttrans-2-Nonenal Covalently Bound to Proteinin Vivo

(2010) Kousuke Ishino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome—Comparison with other biomarkers

(2010) Noriaki Kume et al.   Journal of Cardiology

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

(2010) Andrew J. Syder et al.   JOURNAL OF HEPATOLOGY

Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Delivers Heat Shock Protein 60-Fused Antigen into the MHC Class I Presentation Pathway

(2010) J. Xie et al.   JOURNAL OF IMMUNOLOGY

Pitavastatin Reduces Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands in Hypercholesterolemic Humans

(2010) Tetsuya Matsumoto et al.   LIPIDS

CRP is a novel ligand for the oxidized LDL receptor LOX-1

(2009) Heather H. Shih et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Scavenger Receptors of Endothelial Cells Mediate the Uptake and Cellular Proatherogenic Effects of Carbamylated LDL

(2009) Eugene O. Apostolov et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Palmitic acid enhances lectin-like oxidized LDL receptor (LOX-1) expression and promotes uptake of oxidized LDL in macrophage cells

(2009) Junichi Ishiyama et al.   ATHEROSCLEROSIS

Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet

(2009) Birgit Eichhorn et al.   CARDIOVASCULAR RESEARCH

LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

(2009) Koichi Sugimoto et al.   CARDIOVASCULAR RESEARCH

Mediation of Electronegative Low-Density Lipoprotein Signaling by LOX-1

(2009) Jonathan Lu et al.   CIRCULATION RESEARCH

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+signaling pathways in endothelial cells

(2009) Nobuo Sakamoto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Functional Analysis and Molecular Dynamics Simulation of LOX-1 K167N Polymorphism Reveal Alteration of Receptor Activity

(2009) Silvia Biocca et al.   PLoS One

Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells

(2008) Yo Aramaki et al.   ATHEROSCLEROSIS

Determination of LOX-1-ligand activity in mouse plasma with a chicken monoclonal antibody for ApoB

(2008) Yuko Sato et al.   ATHEROSCLEROSIS

Low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol and the incidence of cardiovascular disease in an urban Japanese cohort study: The Suita study

(2008) Tomonori Okamura et al.   ATHEROSCLEROSIS

Interleukin 18 stimulates release of soluble lectin-like oxidized LDL receptor-1 (sLOX-1)

(2008) Hirokazu Mitsuoka et al.   ATHEROSCLEROSIS

The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells

(2008) Ling Li et al.   ATHEROSCLEROSIS

Prominent Lectin-Like Oxidized Low Density Lipoprotein (LDL) Receptor-1 (LOX-1) Expression in Atherosclerotic Lesions Is Associated with Tissue Factor Expression and Apoptosis in Hypercholesterolemic Rabbits

(2008) Yuji Kuge et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

(2008) Joshua W Knowles et al.   BMC Medical Genetics

Impact of Plasma Oxidized Low-Density Lipoprotein Removal on Atherosclerosis

(2008) Yasushi Ishigaki et al.   CIRCULATION

Oxidized LDL Receptor LOX-1 Binds to C-Reactive Protein and Mediates Its Vascular Effects

(2008) Y. Fujita et al.   CLINICAL CHEMISTRY

Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Attenuates Restenosis of the Artery After Injury

(2008) En-Hui Yao et al.   HYPERTENSION

The Role of Advanced Glycation End Products in Progression and Complications of Diabetes

(2008) Su-Yen Goh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization

(2008) Silvia Biocca et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidized LDL binding to LOX-1 enhances MCP-1 expression in cultured human articular chondrocytes

(2008) M. Akagi et al.   OSTEOARTHRITIS AND CARTILAGE