Osteopontin: a potentially important therapeutic target in cancer

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

(2011) Zhiyong Mi et al.   CARCINOGENESIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

A humanized anti-osteopontin antibody protects from Concanavalin A induced-liver injury in mice

(2011) Kexing Fan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression

(2011) T. M. Tilli et al.   MOLECULAR CANCER RESEARCH

Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients

(2010) Matthias Bache et al.   BMC CANCER

Osteopontin is a marker for cancer aggressiveness and patient survival

(2010) G F Weber et al.   BRITISH JOURNAL OF CANCER

Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival

(2010) Hui-Ping Hsu et al.   CANCER BIOLOGY & THERAPY

A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells

(2010) Hao Liu et al.   CANCER LETTERS

p38 Kinase Is Crucial for Osteopontin-Induced Furin Expression That Supports Cervical Cancer Progression

(2010) V. Kumar et al.   CANCER RESEARCH

Targeted Gene Silencing Using RGD-Labeled Chitosan Nanoparticles

(2010) H. D. Han et al.   CLINICAL CANCER RESEARCH

Differential Expression of Intracellular and Secreted Osteopontin Isoforms by Murine Macrophages in Response to Toll-like Receptor Agonists

(2010) Wei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility

(2010) G. Solinas et al.   JOURNAL OF IMMUNOLOGY

Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells

(2010) Priyanka Sharma et al.   Molecular Cancer

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-κB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

(2010) Mansoor Ahmed et al.   Molecular Cancer

Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

(2010) C. H. Osterreicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines

(2010) Syamal D. Bhattacharya et al.   SURGERY

Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1β through the NF-κB and MAPK pathways in rheumatoid arthritis

(2009) Wenxin Zheng et al.   ARTHRITIS AND RHEUMATISM

A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

(2009) Jianxin Dai et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Senescent Stromal-Derived Osteopontin Promotes Preneoplastic Cell Growth

(2009) E. Pazolli et al.   CANCER RESEARCH

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

(2009) R. Behera et al.   CARCINOGENESIS

Small Integrin-Binding Proteins as Serum Markers for Prostate Cancer Detection

(2009) A. Jain et al.   CLINICAL CANCER RESEARCH

Osteopontin induces β-catenin signaling through activation of Akt in prostate cancer cells

(2009) Brian W. Robertson et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of osteopontin suppresses in vitro and in vivo angiogenesis in endometrial cancer

(2009) Xue-lian Du et al.   GYNECOLOGIC ONCOLOGY

The Hedgehog Pathway Transcription Factor GLI1 Promotes Malignant Behavior of Cancer Cells by Up-regulating Osteopontin

(2009) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymeric Osteopontin Employs Integrin α9β1 as a Receptor and Attracts Neutrophils by Presenting ade NovoBinding Site

(2009) Norihisa Nishimichi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization

(2009) Mohini Rajasagi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lung cancer osteopontin isoforms exhibit angiogenic functional heterogeneity

(2009) Justin D. Blasberg et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells

(2009) J Dai et al.   ONCOGENE

Osteopontin Expression Correlates with Angiogenesis and Survival in Malignant Astrocytoma

(2009) Koviljka Matusan-Ilijas et al.   PATHOLOGY & ONCOLOGY RESEARCH

Primary Breast Carcinoma: Association of Mammographic Calcifications with Osteopontin Expression

(2009) Xiao Wang et al.   RADIOLOGY

Osteopontin Promotes Vascular Endothelial Growth Factor Dependent Breast Tumor Growth and Angiogenesis via Autocrine and Paracrine Mechanisms

(2008) G. Chakraborty et al.   CANCER RESEARCH

Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

(2008) Sandra S. McAllister et al.   CELL

Osteopontin: Role in immune regulation and stress responses

(2008) Kathryn X. Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells

(2008) Akiko Nagasaka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

(2008) C. K. Mason et al.   MOLECULAR CANCER THERAPEUTICS

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

(2008) M. L. Shinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteopontin Expression Is Required for Myofibroblast Differentiation

(2007) Yair Lenga et al.   CIRCULATION RESEARCH

Osteopontin-c is a selective marker of breast cancer

(2007) Mana Mirza et al.   INTERNATIONAL JOURNAL OF CANCER